Bruker Cellular Analysis, Inc. - Quarter Report: 2022 June (Form 10-Q)

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UNITED STATES SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

Form 10-Q

(Mark one)


☒			QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

For the quarterly period ended June 30, 2022


☐			TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

For the transition period from___ to___

Commission file number: 001-39388

Berkeley Lights, Inc.

(Exact name of registrant as specified in its charter)


Delaware			35-2415390
(State or other jurisdiction of incorporation or organization)			(I.R.S. Employer Identification No.)

5858 Horton Street, Suite 320

Emeryville, California 94608

(Address of principal executive offices) (Zip code)

(510) 858-2855

(Registrant’s telephone number, including area code)

Securities registered pursuant to Section 12(b) of the Act:

Title of each class

Trading symbol(s)

Name of each exchange on which registered

Common stock, $0.00005 par value

BLI

The Nasdaq Global Select Market

Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days. Yes ☒ No ☐

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Indicate by check mark whether the registrant has submitted electronically every Interactive Data File required to be submitted pursuant to Rule 405 of Regulation S-T (§232.405 of this chapter) during the preceding 12 months (or for such shorter period that the registrant was required to submit such files). Yes ☒ No ☐

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company, or an emerging growth company. See the definitions of “large accelerated filer,” “accelerated filer,” “smaller reporting company,” and “emerging growth company” in Rule 12b-2 of the Exchange Act.

Large accelerated filer

☒

Accelerated filer

☐

Non-accelerated filer

☐

Smaller reporting company

☐

Emerging growth company

☐

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act.☐

Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act). Yes ☐ No ☒

As of July 31, 2022, 68,283,926 shares of the registrant’s common stock, $0.00005 par value per share, were outstanding.

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BERKELEY LIGHTS, INC.

FORM 10-Q FOR THE QUARTERLY PERIOD ENDED JUNE 30, 2022

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		Page(s)

Part I.	Financial Information	1

Item 1.	Condensed Consolidated Financial Statements (Unaudited)	1

	Condensed Consolidated Balance Sheets as of June 30, 202 2 and December 31, 202 1	1

	Condensed Consolidated Statements of Operations for the three and six months ended June 30, 202 2 and 202 1	2

	Condensed Consolidated Statements of Comprehensive Loss for the three and six months ended June 30, 2022 and 2021	3

	Condensed Consolidated Statements of Changes in Stockholders’ Equity for the three and six months ended June 30, 202 2 and 202 1	4

	Condensed Consolidated Statements of Cash Flows for the six months ended June 30, 202 2 and 202 1	6

	Notes to Condensed Consolidated Financial Statements	7

Item 2.	Management’s Discussion and Analysis of Financial Condition and Results of Operations	23

Item 3.	Quantitative and Qualitative Disclosures about Market Risk	38

Item 4.	Controls and Procedures	38

Part II.	Other Information	40

Item 1.	Legal Proceedings	40

Item 1A.	Risk Factors	40

Item 2.	Unregistered Sales of Equity Securities and Use of Proceeds	40

Item 3.	Defaults Upon Senior Securities	41

Item 4.	Mine Safety Disclosures	41

Item 5	Other Information	41

Item 6.	Exhibits	42

	Signatures	43

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PART I. FINANCIAL INFORMATION

Item 1. Condensed Consolidated Financial Statements (Unaudited).

Berkeley Lights, Inc.

Condensed Consolidated Balance Sheets


	June 30, 2022		December 31, 2021
(In thousands, except share and per share data)	(unaudited)
Assets
Current assets:
Cash and cash equivalents	$	143,024	$	178,096
Short-term marketable securities	9,361		—
Trade accounts receivable	13,815		25,942
Inventory	15,664		14,547
Prepaid expenses and other current assets	10,606		11,985
Total current assets	192,470		230,570
Restricted cash	—		270
Property and equipment, net	29,317		27,992
Operating lease right-of-use assets	24,522		26,060
Other assets	2,397		2,361
Total assets	$	248,706	$	287,253
Liabilities and Stockholders’ Equity
Current liabilities:
Trade accounts payable	$	8,499	$	8,198
Accrued expenses and other current liabilities	11,945		12,425

Deferred revenue	8,694		12,128
Total current liabilities	29,138		32,751
Notes payable	19,794		19,762
Deferred revenue, net of current portion	1,221		2,187
Lease liability, long-term	24,137		24,337

Total liabilities	74,290		79,037
Commitments and contingencies (Note 14)
Stockholders’ equity:

Common stock, $0.00005 par value. Authorized 300,000,000 shares at June 30, 2022 and December 31, 2021; issued and outstanding 68,273,932 and 67,595,535 shares at June 30, 2022 and December 31, 2021, respectively	4		4
Additional paid-in capital	485,212		471,820
Accumulated deficit	(310,781)		(263,608)
Accumulated other comprehensive loss	(19)		—
Total stockholders’ equity	174,416		208,216
Total liabilities and stockholders’ equity	$	248,706	$	287,253

See accompanying notes to these condensed consolidated financial statements.

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Berkeley Lights, Inc.

Condensed Consolidated Statements of Operations (Unaudited)


	Three months ended June 30,				Six months ended June 30,
(In thousands, except share and per share data)	2022		2021		2022		2021
Revenue:
Product revenue	$	9,468	$	13,021	$	19,242	$	26,554
Service revenue	9,682		6,229		20,114		11,324
Total revenue	19,150		19,250		39,356		37,878
Cost of sales:
Product cost of sales	2,614		3,332		5,309		7,035
Service cost of sales	3,610		3,190		7,294		5,664
Total cost of sales	6,224		6,522		12,603		12,699
Gross profit	12,926		12,728		26,753		25,179
Operating expenses:
Research and development	18,178		13,535		35,751		26,562
General and administrative	13,024		11,725		24,740		20,692
Sales and marketing	7,271		5,317		13,082		10,923
Total operating expenses	38,473		30,577		73,573		58,177
Loss from operations	(25,547)		(17,849)		(46,820)		(32,998)
Other income (expense):
Interest expense	(227)		(356)		(451)		(710)
Interest income	53		43		87		109
Other income (expense), net	(22)		34		35		53
Loss before income taxes	(25,743)		(18,128)		(47,149)		(33,546)
Provision for income taxes	4		26		24		43
Net loss	$	(25,747)	$	(18,154)	$	(47,173)	$	(33,589)

Net loss attributable to common stockholders per share, basic and diluted	$	(0.38)	$	(0.27)	$	(0.70)	$	(0.51)
Weighted-average shares used in calculating net loss per share, basic and diluted	67,985,664		66,790,755		67,842,372		66,029,307

See accompanying notes to these condensed consolidated financial statements.

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Berkeley Lights, Inc.

Condensed Consolidated Statements of Comprehensive Loss (Unaudited)


	Three months ended June 30,				Six months ended June 30,
(In thousands)	2022		2021		2022		2021

Net loss	$	(25,747)	$	(18,154)	$	(47,173)	$	(33,589)
Other comprehensive loss:
Unrealized loss on marketable securities, net of tax	(19)		—		(19)		—
Other comprehensive loss:	(19)		—		(19)		—
Comprehensive loss	$	(25,766)	$	(18,154)	$	(47,192)	$	(33,589)

See accompanying notes to these condensed consolidated financial statements.

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Berkeley Lights, Inc.

Condensed Consolidated Statements of Changes in Stockholders’ Equity (Unaudited)


	Three Months Ended June 30, 2022
	Common Stock			Additional Paid-in Capital		Accumulated Deficit		Accumulated Other Comprehensive Loss		Total Stockholders' Equity
(In thousands, except share data)	Shares	Amount
Balances at March 31, 2022	67,820,115	$	4	$	478,231	$	(285,034)	$	—	$	193,201
Shares issued in connection with:
Exercise of stock options	181,013	—		354		—		—		354
Vesting of restricted stock units	272,804	—		—		—		—		—

Stock-based compensation	—	—		6,627		—		—		6,627
Other comprehensive loss	—	—		—		—		(19)		(19)
Net loss	—	—		—		(25,747)		—		(25,747)
Balances at June 30, 2022	68,273,932	$	4	$	485,212	$	(310,781)	$	(19)	$	174,416


	Three Months Ended June 30, 2021
	Common Stock			Additional Paid-in Capital		Accumulated Deficit		Accumulated Other Comprehensive Loss		Total Stockholders' Equity
(In thousands, except share data)	Shares	Amount
Balances at March 31, 2021	66,384,736	$	4	$	449,681	$	(207,319)	$	—	$	242,366
Shares issued in connection with:
Exercise of stock options	644,610	—		1,985		—		—		1,985
Vesting of restricted stock units	14,191	—		—		—		—		—
Stock-based compensation	—	—		5,642		—		—		5,642

Net loss	—	—		—		(18,154)		—		(18,154)
Balances at June 30, 2021	67,043,537	$	4	$	457,308	$	(225,473)	$	—	$	231,839

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	Six Months Ended June 30, 2022
	Common Stock			Additional Paid-in Capital		Accumulated Deficit		Accumulated Other Comprehensive Loss		Total Stockholders' Equity
(In thousands, except share data)	Shares	Amount
Balances at December 31, 2021	67,595,535	$	4	$	471,820	$	(263,608)	$	—	$	208,216
Shares issued in connection with:
Exercise of stock options	262,667	—		766		—		—		766
Vesting of restricted stock units	300,384	—		—		—		—		—

Employee stock purchase plan	115,346	—		610		—		—		610
Stock-based compensation	—	—		12,016		—		—		12,016
Other comprehensive loss	—	—		—		—		(19)		(19)
Net loss	—	—		—		(47,173)		—		(47,173)
Balances at June 30, 2022	68,273,932	$	4	$	485,212	$	(310,781)	$	(19)	$	174,416


	Six Months Ended June 30, 2021
	Common Stock			Additional Paid-in Capital		Accumulated Deficit		Accumulated Other Comprehensive Loss		Total Stockholders' Equity
(In thousands, except share data)	Shares	Amount
Balances at December 31, 2020	64,486,246	$	3	$	436,662	$	(191,884)	$	—	$	244,781
Shares issued in connection with:
Exercise of stock options	2,422,740	1		8,346		—		—		8,347
Vesting of restricted stock units	19,191	—		—		—		—		—
Employee stock purchase plan	115,360			2,157				—		2,157
Stock-based compensation	—	—		10,143		—		—		10,143

Net loss	—	—		—		(33,589)		—		(33,589)
Balances at June 30, 2021	67,043,537	$	4	$	457,308	$	(225,473)	$	—	$	231,839

See accompanying notes to these condensed consolidated financial statements.

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Berkeley Lights, Inc.

Condensed Consolidated Statements of Cash Flows (Unaudited)


	Six months ended June 30,
(In thousands)	2022		2021

Cash flows from operating activities:
Net loss	$	(47,173)	$	(33,589)
Adjustments to reconcile net loss to cash used in operating activities:
Depreciation	4,431		2,654
Stock-based compensation	11,958		10,123
Amortization of operating lease right-of-use assets	1,538		994
Non-cash interest and other expense related to debt and note receivable agreements	32		36
Provision for excess and obsolete inventory	479		330
Loss on disposal and impairment of property and equipment	27		31

Other non-cash	271		—

Changes in operating assets and liabilities:
Trade accounts receivable	12,128		(6,820)
Inventory	(1,539)		(5,710)
Prepaid expenses, other current assets and other assets	1,340		(639)
Trade accounts payable	1,000		4,512
Deferred revenue	(4,400)		2,942
Accrued expenses and other current liabilities	(585)		1,872
Operating lease liabilities	(95)		(831)

Net cash used in operating activities	(20,588)		(24,095)
Cash flows from investing activities:
Purchase of property and equipment	(6,758)		(4,382)
Purchase of marketable securities	(9,372)		—

Net cash used in investing activities	(16,130)		(4,382)
Cash flows from financing activities:



Payment of debt issuance costs	—		(358)
Proceeds from issuance of common stock upon exercise of stock options	766		8,347
Proceeds from issuance of common stock under employee stock purchase plan	610		2,157
Net cash provided by financing activities	1,376		10,146
Net decrease in cash and cash equivalents and restricted cash	(35,342)		(18,331)
Cash and cash equivalents and restricted cash at beginning of period	178,366		233,678
Cash and cash equivalents and restricted cash at end of period	$	143,024	$	215,347

See accompanying notes to these condensed consolidated financial statements.

Berkeley Lights, Inc.

Notes to Condensed Consolidated Financial Statements

(Unaudited)

(1)The Company and Basis of Presentation

Description of Business

Berkeley Lights, Inc. (the “Company” or “Berkeley Lights”) is a leading Digital Cell Biology company focused on enabling and accelerating the rapid development and commercialization of biotherapeutics and other cell-based products. Berkeley Lights’ platform is a fully integrated, end-to-end solution, comprised of proprietary consumables, including the Company’s OptoSelect chips and reagent kits, advanced automation systems and advanced application and workflow software.

Berkeley Lights and its consolidated subsidiaries are hereinafter referred to as the “Company.” The Company’s headquarters are in Emeryville, California.

Basis of Presentation

The accompanying unaudited condensed consolidated financial statements (the “condensed consolidated financial statements”) have been prepared in accordance with generally accepted accounting principles in the United States of America.

Liquidity

The Company has experienced losses from its operations since its inception and has relied primarily on equity and debt financing to fund its operations to date. For the three and six months ended June 30, 2022, the Company had a consolidated net loss of $25.7 million and $47.2 million, respectively, and as of June 30, 2022 had an accumulated deficit of $310.8 million. Unrestricted cash, cash equivalents and marketable securities was $152.4 million at June 30, 2022. Management expects to continue to incur significant expenses for the foreseeable future and to incur operating losses in the near term while the Company makes investments to support its anticipated growth. The Company believes that its cash, cash equivalents and marketable securities balance as of June 30, 2022 provides sufficient capital resources to continue its operations for at least 12 months from the issuance date of the accompanying consolidated financial statements.

(2)Summary of Significant Accounting Policies

Significant Accounting Policies

The Company’s significant accounting policies are disclosed in its Annual Report on Form 10-K for the year ended December 31, 2021 filed with the Securities and Exchange Commission and have not materially changed during the six months ended June 30, 2022, with the exception of the accounting policies as described further below.

Short-Term Marketable Securities

The Company designates investments in debt securities as available-for-sale. Available-for-sale debt securities with original maturities of three months or less from the date of purchase are classified within cash and cash equivalents. Available-for-sale debt securities with original maturities longer than three months are available to fund current operations and are classified as marketable securities within “current assets” on the Company’s condensed consolidated balance sheets. The Company records these securities at fair value and accounts for the net unrealized gains and losses related to them as part of “other comprehensive loss” on its condensed consolidated statement of comprehensive loss. The Company records realized gains and losses on the sale of its marketable securities in “Other income, net” in its condensed consolidated statement of operations.

Berkeley Lights, Inc.

Notes to Condensed Consolidated Financial Statements

(Unaudited)

At each reporting date, the Company performs an evaluation of impairment of its short-term available-for-sale marketable debt securities to determine if the fair value of its investment is less than its amortized cost basis. Impairment is assessed at the individual security level. Factors considered in determining whether an investment is impaired include the Company’s intent and ability to hold the investment until the recovery of its amortized cost basis, any historical failure of the issuer to make scheduled interest or principal payments, any change to the rating of the security by a rating agency, any adverse legal or regulatory events affecting the issuer or issuer’s industry, and any significant deterioration in economic conditions.

Stock-Based Compensation

The Company maintains an incentive compensation plan under which stock options and restricted stock units (“RSU”) are granted to employees and non-employee consultants.

Stock-based compensation expense is based on the grant date fair value of the award. The Company determines the fair value of RSUs based on the closing value of its stock price listed on the Nasdaq at the date of the grant.

The Company estimates the fair value of the majority of stock option awards on the grant date using the Black-Scholes option-pricing model. For option awards that include a goal tied to the Company share price (i.e. a market condition) the Company uses a Monte Carlo simulation to estimate the fair value.

The fair value of stock options and RSUs with only a service condition is recognized as compensation expense on a straight-line basis over the requisite service period in which the awards are expected to vest and forfeitures are recognized as they occur.

Stock options and RSUs that include a service condition and a performance condition are considered expected to vest when the performance condition is probable of being met. Compensation expense associated with performance awards that are determined to be probable of achievement is recognized over the requisite service period on a tranche-by-tranche basis.

For performance stock options and awards not initially assessed as probable of achievement, the Company records a cumulative adjustment to compensation expense in the period the Company changes its determination that a performance condition becomes probable of being achieved. The Company ceases recognition of compensation expense in any periods where the Company determines the attainment of a performance condition is no longer probable. If the performance goals are determined to be improbable, any previously recognized compensation expense is reversed.

The fair value of stock options with a market condition is recognized over the requisite service period for each tranche of the award and is recognized regardless of whether (or to what extent) the market condition is ultimately achieved.

(3)Marketable Securities

Short-Term Marketable Securities

The Company invests in available-for-sale marketable debt securities consisting of commercial paper and U.S. government securities with contractual maturities due within one year. The Company did not hold any investments in marketable debt securities as of December 31, 2021.

Berkeley Lights, Inc.

Notes to Condensed Consolidated Financial Statements

(Unaudited)

The following table summarizes the amortized costs and carrying value of the Company’s available-for-sale marketable debt securities, by major security type, as of June 30, 2022 (in thousands):


	As of June 30, 2022
	Amortized Cost		Unrealized Gains		Unrealized Losses		Fair Value
Commercial paper	$	5,395	$	—	$	(8)	$	5,387
U.S. government securities	3,982		—		(8)		3,974
Total	$	9,377	$	—	$	(16)	$	9,361

At each reporting date, the Company performs an evaluation of impairment to determine if any unrealized losses are the result of credit losses. Impairment is assessed at the individual security level. Unrealized losses on available-for-sale debt securities as of June 30, 2022 were not significant and were primarily market driven due to changes in interest rates, and not due to increased credit risk associated with specific securities. Accordingly, the Company did not record an allowance for credit losses on these short term investments as of June 30, 2022.

(4)Significant Risks and Uncertainties Including Business and Credit Concentrations

Financial instruments that potentially subject the Company to concentrations of credit risk consist primarily of cash equivalents, short-term available-for-sale debt securities and trade receivables. The Company’s cash, cash equivalents and short-term available-for-sale marketable securities are held by large, credit worthy financial institutions. The Company invests its excess cash in money market funds and short-term available-for-sale debt securities with the primary objective of facilitating liquidity and capital preservation. The Company has established guidelines relative to credit ratings, diversification and maturities that seek to maintain safety and liquidity. Deposits in these banks may exceed the amounts of insurance provided on such deposits. To date, the Company has not experienced any losses on its deposits of cash, cash equivalents and marketable securities.

The Company controls credit risk through credit approvals and monitoring procedures. The Company performs periodic credit evaluations of its customers and generally does not require collateral. Accounts receivable are recorded net of an allowance for doubtful accounts. The allowance for doubtful accounts is based on management’s assessment of the collectability of specific customer accounts and the aging of the related invoices and represents the Company’s best estimate of expected credit losses in its existing trade accounts receivable. At each of June 30, 2022 and December 31, 2021, the Company had not recorded any material allowance for doubtful accounts.

Most of the Company’s customers are located in the United States and Asia Pacific. For the three months ended June 30, 2022, three customers accounted for 20%, 11%, and 10% of revenue. For the six months ended June 30. 2022, three customers accounted for 16%, 11% and 10% of revenue. For the three months ended June 30, 2021, three customers accounted for 27%, 18% and 11%, of revenue. For the six months ended June 30, 2021, three customers accounted for 14%, 11% and 10% of revenue.

As of June 30, 2022, three customers comprised 27%, 12% and 11% of accounts receivable. As of December 31, 2021, three customers accounted for 15%, 11% and 11% of accounts receivable.

Berkeley Lights, Inc.

Notes to Condensed Consolidated Financial Statements

(Unaudited)

(5)Revenue From Contracts With Customers

Disaggregation of Revenue

The following table depicts the disaggregation of revenue by type of customer or sales channel and market segment as defined by nature of workflows and activities of the end customer (in thousands):


	Three months ended June 30,				Six months ended June 30,
	2022		2021		2022		2021
Type of Sales Channel
Direct sales channel	$	14,067	$	10,103	$	29,553	$	20,542
Distributor channel	5,083		9,147		9,803		17,336
Net revenues	$	19,150	$	19,250	$	39,356	$	37,878

Market
Antibody therapeutics	$	12,984	$	13,672	$	27,209	$	28,786
Synthetic biology	2,067		1,856		4,539		3,840
Agricultural biology	1,854		—		3,345		—
Gene therapy	2,028		2,058		3,802		3,283
Cell therapy	217		1,664		461		1,969
Net revenues	$	19,150	$	19,250	$	39,356	$	37,878

Revenues by market are determined by the revenue associated with workflows that the Company’s customers are utilizing, primarily on the Company’s Beacon platform, or by the nature of the workflows that the Company is developing under strategic partnerships and services agreements. Revenues by geographical markets are presented in Note 16 to these condensed consolidated financial statements.

Performance Obligations

A significant number of the Company’s product and service sales, as well as its feasibility study arrangements, are short-term in nature with a contract term of one year or less. For those contracts, the Company has utilized the practical expedient in ASC 606-10-50-14 exempting the Company from disclosure of the transaction price allocated to remaining performance obligations if the performance obligation is part of a contract that has an original expected duration of one year or less.

As of June 30, 2022, the aggregate amount of remaining performance obligations that are unsatisfied or partially unsatisfied related to customer contracts in excess of one year was $6.4 million, which is included in deferred revenue on the Company’s condensed consolidated balance sheets, of which approximately 20% is expected to be recognized as revenue in the next 12 months, with the remainder recognized afterwards.

Berkeley Lights, Inc.

Notes to Condensed Consolidated Financial Statements

(Unaudited)

Contract Balances

The following table provides information about receivables, contract assets and deferred revenue from contracts with customers (in thousands):


	June 30, 2022		December 31, 2021

Trade accounts receivable	$	13,815	$	25,942
Contract assets, which are included in “Prepaid expenses and other current assets”	$	3,765	$	1,736
Contract assets, long-term, which are included in “Other assets”	$	996	$	1,070
Deferred revenue (current)	$	8,694	$	12,128
Deferred revenue (non-current)	$	1,221	$	2,187

The contract liabilities of $9.9 million and $14.3 million as of June 30, 2022 and December 31, 2021, respectively, consisted of deferred revenue related to extended warranty service agreements, strategic partnerships and services agreements and advanced automation systems arrangements. Revenue recorded during the three and six months ended June 30, 2022 included $2.7 million and $9.9 million, respectively, of previously deferred revenue that was included in contract liabilities as of December 31, 2021.

Sales-type Lease Arrangements

The Company also enters into sales-type lease arrangements with certain qualified customers. Revenue related to lease elements from sales-type leases is presented as product revenue and was none for the three and six months ended June 30, 2022, respectively, and $1.0 million and $2.7 million for the three and six months ended June 30, 2021, respectively.

The following table presents the future maturity of the Company’s fixed-term customer leases and reconciles the undiscounted cash flows from the amounts due from customers under such arrangements as of June 30, 2022 (in thousands):


Year ending December 31,	Sales-Type Leases
Remainder of 2022	$	1,212
2023	445
2024	853

Total undiscounted cash flows	2,510
Less: unearned income	305
Total amounts due from customers	$	2,205

Berkeley Lights, Inc.

Notes to Condensed Consolidated Financial Statements

(Unaudited)

(6) Balance Sheet Accounts

Inventory

The following table shows the components of inventory (in thousands):


	June 30, 2022		December 31, 2021

Raw materials	$	10,861	$	8,296
Finished goods	4,803		6,251
Total	$	15,664	$	14,547

Prepaid expenses and other current assets

The following table shows the components of prepaid expenses and other current assets (in thousands):


	June 30, 2022		December 31, 2021

Contract asset	$	3,765	$	1,736
Vendor deposits	2,679		2,802
Deferred costs	537		561
Prepaid insurance	399		2,944
Other (1)	3,226		3,942
Total	$	10,606	$	11,985

(1) Other includes primarily prepaid rent expenses, software licenses and prepaid VAT.

Accrued expenses and other current liabilities

The following table shows the components of accrued expenses and other current liabilities (in thousands):


	June 30, 2022		December 31, 2021

Accrued payroll and employee related expenses	$	6,400	$	6,757
Lease liability – short-term	3,046		2,941
Accrued product warranty	752		1,085
Accrued legal expenses	1,087		504
Other (1)	660		1,138
Total	$	11,945	$	12,425

(1) Other includes primarily accrued income taxes, sales taxes, accrued royalties and other miscellaneous accruals.

(7)Fair Value of Financial Instruments

Fair value is defined as the price that would be received to sell an asset or paid to transfer a liability (an exit price) in an orderly transaction between market participants at the reporting date. The categorization of a financial instrument within the valuation hierarchy is based on the lowest level of input that is significant to the fair value measurement.

The fair value of the Company’s assets and liabilities, including cash equivalents and marketable debt securities, are measured at fair value on a recurring basis. As of June 30, 2022 the Company held investments in securities classified as cash equivalents. The carrying amounts of the Company’s cash, accounts receivable, prepaid expenses, other current assets, accounts payable, accrued expenses and other current liabilities as of June 30, 2022 and December 31, 2021 approximate fair value due to their relatively short maturities.

Berkeley Lights, Inc.

Notes to Condensed Consolidated Financial Statements

(Unaudited)

The following tables set forth the fair value of the Company’s financial assets and liabilities by level within the fair value hierarchy (in thousands):


	June 30, 2022		Quoted Prices in Active Markets for Identical Assets (Level 1)		Significant Other Observable Inputs (Level 2)		Significant Unobservable Inputs (Level 3)
Cash equivalents:
Money market funds	$	32,233	$	32,233	$	—	$	—
Commercial paper	22,595		—		22,595		—
U.S. government securities	5,986		—		5,986		—
Total cash equivalents	60,814		32,233		28,581		—

Debt securities, available for sale:
Commercial paper	5,387		—		5,387		—
U.S. government securities	3,974		—		3,974		—
Total debt securities, available for sale	9,361		—		9,361		—
Total assets measured at fair value	$	70,175	$	32,233	$	37,942	$	—


	December 31, 2021		Quoted Prices in Active Markets for Identical Assets (Level 1)		Significant Other Observable Inputs (Level 2)		Significant Unobservable Inputs (Level 3)

Cash equivalents:
Money market funds	$	25,138	$	25,138	$	—	$	—
Total cash equivalents	$	25,138	$	25,138	$	—	$	—

The carrying values and fair values of the Company’s financial instruments not measured at fair value were as follows (in thousands):


	June 30, 2022				December 31, 2021
	Carrying Value		Fair Value		Carrying Value		Fair Value

Long-term debt, including current maturities	$	19,794	$	19,287	$	19,762	$	19,298

The Company estimated the fair value of its long-term debt using a market-based approach that considers an average cost of debt. The Company has incorporated its own credit risk for all liability fair value measurements. Such fair value measurements are considered Level 2 under the fair value hierarchy.

The Company did not have any transfers of financial assets measured at fair value on a recurring basis between the levels of the fair value measurement hierarchy during the periods presented.

Berkeley Lights, Inc.

Notes to Condensed Consolidated Financial Statements

(Unaudited)

(8)Property and Equipment, net

Property and equipment, net comprised the following (in thousands):


	June 30, 2022		December 31, 2021

Equipment, tooling and molds	$	38,599	$	33,972
Computer software and equipment	2,929		3,019
Furniture, fixtures and other	1,957		1,891
Leasehold improvements	10,820		6,105
Construction in process	778		4,803
Total property and equipment	55,083		49,790
Less: Accumulated depreciation	(25,766)		(21,798)
Property and equipment, net	$	29,317	$	27,992

Total depreciation expense for the three and six months ended June 30, 2022 was $2.5 million and $4.4, respectively. Total depreciation expense for three and six months ended June 30, 2021 was $1.4 million and $2.7 million, respectively.

During the three and six months ended June 30, 2022 and 2021 losses on the impairment and disposal of property and equipment was not material.

(9)Leases

The Company leases office, manufacturing, distribution and laboratory facilities in Emeryville, California under multiple operating leases. During the third quarter of 2021, the Company extended the term for its leases related to the facilities in Emeryville and these leases will now expire in 2029. Also, during the third quarter of 2021, the Company entered into a seven year lease of space for office and laboratory operations in Lexington, Massachusetts.

The Company also leases two facilities in Shanghai, China for office and laboratory facilities under operating lease agreements that were entered into in July 2020. These leases expire at various dates, the latest of which is August 2023.

Berkeley Lights, Inc.

Notes to Condensed Consolidated Financial Statements

(Unaudited)

Future payments associated with the Company’s operating lease liabilities as of June 30, 2022 is as follows (in thousands):


	Operating leases

Undiscounted lease payments for the year ending December 31,
Remainder of 2022	$	2,101
2023	4,273
2024	4,355
2025	4,486
2026	4,621
Thereafter	12,223
Total undiscounted lease payments	32,059
Less: implied interest	(4,811)
Less: tenant improvement allowances receivable	(65)
Present value of operating lease payments	27,183
Less: current portion (1)	(3,046)
Total long-term operating lease liabilities	$	24,137

(1) Included in the balance sheet caption “Accrued expenses and other current liabilities.”

Rent expense for the three and six months ended June 30, 2022 was $1.4 million and $2.5 million, respectively. Rent expense for the three and six months ended June 30, 2021 was $0.9 million and $1.7 million, respectively. Under the terms of the lease agreements, the Company is also responsible for certain variable lease payments that are not included in the measurement of the lease liability. Variable lease payments for operating leases were $1.0 million and $1.8 million for the three and six months ended June 30, 2022, respectively, including non-lease components such as common area maintenance fees. Variable lease payments for operating leases were $0.6 million and $1.1 million for the three and six months ended June 30, 2021, respectively, including non-lease components such as common area maintenance fees.

The following information represents supplemental disclosure for the statement of cash flows related to operating leases (in thousands):


	Six months ended June 30, 2022		Six months ended June 30, 2021


Right-of-use assets obtained for new operating lease liabilities	$	—	$	—
Cash paid for amounts included in the measurement of lease liabilities	$	1,070	$	796

The following summarizes additional information related to operating leases:


	June 30, 2022		December 31, 2021

Weighted-average remaining lease term (years)	7.02		7.51
Weighted-average discount rate	4.67	%	4.67	%

The Company also enters into leasing transactions in which the Company is the lessor, which to date have been classified as sales-type leases. See Note 5 of these condensed consolidated financial statements for the related lease disclosures.

Berkeley Lights, Inc.

Notes to Condensed Consolidated Financial Statements

(Unaudited)

(10)Notes Payable

On May 23, 2018, the Company entered into a Loan and Security Agreement with East West Bank (“EWB”) providing it the ability to borrow up to $20.0 million. The loan facility was fully drawn as of May 23, 2018.

On June 30, 2021, the Company entered into an Amended and Restated Loan and Security Agreement (the “Agreement”) with EWB. Pursuant to the Agreement, EWB provided a $20.0 million term loan (the “Term Loan”) which was used to refinance the term loan outstanding under the Loan and Security Agreement dated May 23, 2018. The Term Loan matures in 48 months and bears a fixed interest rate of 4.17%. The Term Loan has an initial interest-only period of 24 months, which can be extended to up to 36 months based on the achievement of certain liquidity measures, and can be pre-paid without penalty at any time.

The Agreement grants EWB a security interest in and liens on all assets of the Company, excluding intellectual property, which is subject to a double negative pledge. In addition, certain other terms of the original agreements as previously in effect were amended by the Agreement, including certain financial covenants. The Amended and Restated Loan and Security Agreement was accounted for as a debt modification and the Company capitalized incremental debt issuance costs.

Furthermore, the Agreement also provided the Company with a new $10.0 million revolving credit (the “Revolving Line”), which bears interest on the outstanding daily balance thereof of 0.70% above the Prime Rate (as defined in the Agreement). No amounts were outstanding under the Revolving Line as of June 30, 2022.

The Agreement contains certain financial and non-financial covenants. As of June 30, 2022, the Company was in compliance with the terms and covenants of the Agreement.

The following is a schedule of payments due on notes payable as of June 30, 2022 (in thousands):


	June 30, 2022
Year Ending December 31:
Remainder of 2022	$	426
2023	6,617
2024	10,406
2025	4,210

Total payments due	21,659
Less:
Interest payments, loan discounts and financing costs	(1,865)
Current portion, less loan discounts and financing costs	—
Notes payable, net of current portion	$	19,794

Total interest cost incurred for the three and six months ended June 30, 2022 was $0.2 million and $0.5 million, respectively. Total interest cost incurred for the three and six months ended June 30, 2021 was $0.4 million and $0.7 million, respectively.

Berkeley Lights, Inc.

Notes to Condensed Consolidated Financial Statements

(Unaudited)

(11)Stock Compensation Plans

Stock-based compensation

Stock-based compensation related to the Company's stock-based awards was recorded as an expense and allocated as follows (in thousands):


	Three months ended June 30,				Six months ended June 30,
	2022		2021		2022		2021

Cost of sales	$	68	$	63	$	119	$	105
Research and development	2,292		1,599		3,873		2,660
General and administrative	2,318		2,497		4,529		3,869
Sales and marketing	1,887		1,470		3,437		3,489
Total stock-based compensation	$	6,565	$	5,629	$	11,958	$	10,123

Stock-based compensation capitalized in inventory was not material as of June 30, 2022 and December 31, 2021.

Option Repricing

On May 19, 2022, the Company’s Board of Directors elected to reprice all outstanding stock options granted to non-executive employees of the Company under the Berkeley Lights, Inc. 2020 Incentive Plan with a strike price above the closing price of the Company’s common stock as reported on Nasdaq as of May 19, 2022 (which was $4.91). There were no other modifications to these options, including vesting schedules. Options representing 763,307 underlying shares were included in this repricing and the total incremental expense associated with the modification of these options was $1.5 million, of which $0.5 million was recorded in the second quarter of 2022.

In addition, non-executive employees with outstanding options granted under the Berkeley Lights 2011 Equity Incentive Plan with a strike price above the closing price of the Company’s common stock as reported on Nasdaq as of May 19, 2022 were granted an RSU for every two stock options held with a strike price above the closing price as of May 19, 2022. These RSUs were granted on June 1, 2022 and vest in full on June 1, 2024. An aggregate total of 353,625 RSUs were granted to such employees resulting in $1.5 million of compensation expense, of which approximately $55 thousand was recorded in the second quarter of 2022.

CEO Equity Grant

On March 10, 2022, the Company granted the newly appointed Chief Executive Officer of the Company 1,017,177 RSUs, 339,059 stock options and 678,118 performance-based stock options (“PSOs”). The RSUs and stock options vest quarterly over 3 years and the stock options have a 10 year term.

The PSOs have a 7-year performance period, a 10-year term and vest based upon certain market conditions and a continued service-based requirement. Market condition-related vesting is triggered based on the Company’s stock price reaching certain goals that range from two to 20 times the Company share price on the date of grant.

Although no awards will vest until a market condition is satisfied, as of March 31, 2022 the Company began recording stock-based compensation expense for each vesting tranche based on the estimated achievement date of the specified stock price target. The valuation and probability of achievement for each tranche is determined using a Monte Carlo simulation. The same Monte Carlo simulation is used as the basis for determining the expected achievement date. As the probability of achievement is factored in as part of the Monte Carlo simulation, the expense for these tranches will be recognized concurrently over each tranche’s estimated achievement date even if

Berkeley Lights, Inc.

Notes to Condensed Consolidated Financial Statements

(Unaudited)

some or all of the options never vest. If the related market condition for a tranche is achieved earlier than expected, all unamortized expense for such tranche will be recognized immediately. As of June 30, 2022, none of the PSOs had vested.

(12)Income Taxes

The Company’s provision for income taxes was $4,000 and $24,000, respectively, for the three and six months ended June 30, 2022 and $26,000 and $43,000, respectively, for the three and six months ended June 30, 2021. For the three and six months ended June 30, 2022 and 2021, income from operations before taxes consisted of amounts related to U.S. operations and the Company’s foreign operations. The Company maintains a full valuation allowance on its deferred tax assets, and intends to do so until there is sufficient evidence to support the reversal of all or some portion of this allowance.

(13)Statements of Cash Flows

The supplemental cash flow information consists of the following (in thousands):


	Six months ended June 30,
	2022		2021
Cash paid for interest	$	278	$	681
Cash paid for income taxes	$	—	$	3

Non-cash investing and financing activities

Inventory transferred to property and equipment (1)	$	—	$	3,827
Change in accounts payable and accrued liabilities related to purchases of property and equipment	$	(699)	$	723

(1) The non-cash transfer of inventory to property and equipment principally relates to Beacons that were transferred to the Company’s BioFoundry operations in the first and second quarter of 2021. As a result of the growth of the Company’s BioFoundry operations, including growth in the number of Beacons used to fulfill strategic partnerships and services agreements, beginning in the third quarter of 2021, Beacons that at inception are planned to be used in the Company’s BioFoundry operations will be categorized as “Purchase of property and equipment.”

Berkeley Lights, Inc.

Notes to Condensed Consolidated Financial Statements

(Unaudited)

(14)Commitments and Contingencies

Legal Proceedings

From time to time, the Company may be involved in legal and administrative proceedings and claims of various types. The Company records a liability in its financial statements for these matters when a loss is known and considered probable and the amount can be reasonably estimated. The Company does not recognize gain contingencies until they are realized. Legal costs incurred relating to loss contingencies are expensed as incurred.

AbCellera Biologics Litigation

In July 2020, AbCellera Biologics Inc. (“AbCellera”) filed a complaint in the United States District Court for the District of Delaware, alleging that the Company infringed and continues to infringe, directly and indirectly, the following patents exclusively licensed by AbCellera by making, using, offering for sale, selling and/or importing the Company’s Beacon and Culture Station instruments and the OptoSelect chips, and sale of the Opto Plasma B Discovery Workflow: U.S. Patent Nos. 10,107,812, 10,274,494, 10,466,241, 10,578,618, 10,697,962, 10,087,408, 10,421,936 and 10,704,018 (“AbCellera I”).

In August 2020, AbCellera filed a second complaint in the United States District Court for the District of Delaware, making the same allegations with regard to U.S. Patent Nos. 10,718,768, 10,738,270, 10,746,737, and 10,753,933 (“AbCellera II”). In September 2020, AbCellera filed amended complaints in each of AbCellera I and AbCellera II adding The University of British Columbia (“UBC”) as a named plaintiff. Also in September 2020, AbCellera and UBC filed a third complaint in the United States District Court for the District of Delaware, making the same allegations with regard to U.S. Patent Nos. 10,775,376, 10,775,377, and 10,775,378 (“AbCellera III”). AbCellera and UBC are seeking, among other things, judgment of infringement, a permanent injunction and damages (including lost profits, a reasonable royalty, reasonable costs and attorney’s fees and treble damages for willful infringement). In addition to procedural motions, the Company has filed an answer and counterclaims in response to each of the AbCellera I, AbCellera II and AbCellera III lawsuits. The Company’s counterclaims in each lawsuit include counts for declaratory judgment of non-infringement of the asserted patents, for declaratory judgment of invalidity of the asserted patents and for declaratory judgment of unenforceability of the asserted patents due to inequitable conduct. The Company filed a motion to transfer the AbCellera I, AbCellera II and AbCellera III lawsuits to the United States District Court for the Northern District of California, which was granted and where the lawsuits have been consolidated and are now pending (the “consolidated lawsuit”). On May 6, 2021 and pursuant to Court Order, AbCellera and UBC reduced, without prejudice, the asserted patents in the consolidated lawsuit to the following: US Patent Nos. 10,087,408, 10,421,936, 10,738,270, 10,697,962, 10,753,933, 10,775,376 and 10,775,378.

On July 1, 2021, the court granted the Company’s motion to amend its answer and counterclaims to add federal and state unfair competition counterclaims against AbCellera Biologics; on July 22, 2021, the Company filed its amended answer and counterclaims. Also on July 1, 2021 the court issued a Case Management Order that, among other things, requires AbCellera and UBC to reduce the number of asserted patents to no more than two, and the total asserted patent claims to no more than four per patent prior to the trial.

Also in July 2021, the Company filed petitions for Inter Partes Review (“IPR”) with the United States Patent & Trademark Office (“USPTO”), challenging the validity of various asserted claims of U.S. Patent No. 10,087,408 and all asserted claims of U.S. Patent No. 10,421,936, then filed a motion in the district court to stay the consolidated lawsuit pending the outcome of the IPR proceedings. In August 2021, the Company filed a third petition for IPR with the USPTO, challenging the validity of all asserted claims of U.S. Patent No. 10,739,270. Also in August 2021, the court granted the Company’s motion to stay the consolidated AbCellera I, AbCellera II, and AbCellera III lawsuits pending the outcome of the IPR proceedings.

Berkeley Lights, Inc.

Notes to Condensed Consolidated Financial Statements

(Unaudited)

In January 2022, the Patent Trial and Appeal Board (“PTAB”) of the USPTO issued a decision instituting IPR on U.S. Patent No. 10,087,408 and a decision denying IPR on U.S. Patent No. 10,421,936. In February 2022, the PTAB issued a decision denying IPR on U.S. Patent No. 10,739,270. In May 2022, UBC filed a Patent Owner’s Response (“POR”) in the IPR of U.S. Patent No. 10,087,408. Also in May 2022, AbCellera and UBC filed a motion in the United States District Court for the Northern District of California to lift the stay of the consolidated AbCellera I, AbCellera II, and AbCellera III lawsuits, citing lack of institution of the IPRs of U.S. Patent Nos. 10,421,936 and 10,739,270. The Company has opposed the motion, and a hearing on the motion to lift the stay is scheduled for August 2022.

In August 2020, the Company filed a complaint in the United States District Court for the Northern District of California against AbCellera and Lineage BioSciences, Inc., an entity previously acquired by AbCellera (“AbCellera IV”). The complaint included two counts of unfair competition and one count of a declaratory judgment of non-infringement of U.S. Patent No. 10,058,839. The Company was seeking, among other things, damages and a judgment of non-infringement. In October 2020, the Company filed an amended complaint asserting the same three counts and AbCellera and Lineage filed a motion to dismiss the amended complaint, which was granted, without prejudice, in part. In light of the Company’s amended answer and counterclaims in the consolidated lawsuits, which were amended to include its federal and state unfair competition claims as discussed above, in July 2021 the Company filed a notice of dismissal without prejudice in the AbCellera IV lawsuit, resulting in its termination.

The Company believes that the patent assertions by AbCellera and UBC are without merit and intends to defend itself vigorously. The Company also intends to proceed with its claims and counterclaims against AbCellera and UBC. Outcomes in litigation can be uncertain and it is possible a court may disagree with the Company’s positions. An adverse determination in these lawsuits could subject the Company to significant liabilities, require it to seek licenses from or pay royalties to AbCellera and/or UBC, or prevent it from manufacturing, selling or using certain of its products, any of which could have a material adverse effect on the Company’s business, financial condition, results of operations and prospects.

Securities Class Action

In December 2021, Victor J. Ng filed a securities class action complaint (the “Securities Class Action”), which was amended on July 25, 2022. The Securities Class Action is on behalf of all persons who purchased or otherwise acquired: (a) Berkeley Lights common stock pursuant and/or traceable to certain July 2020 IPO offering documents and/or (b) securities of Berkeley Lights between July 17, 2020 and January 5, 2022, inclusive. The complaint alleges claims under §§10(b) and 20(a) of the Securities Exchange Act of 1934 and Rule 10b-5 promulgated thereunder as well as §§11, 12(a)(2) and 15 of the Securities Act of 1933. It names as defendants the Company, certain of the Company’s current and former senior executives and directors, the underwriter firms that sponsored the Company’s July 2020 IPO, and three firms that invested in the Company. The Company believes that the assertions in the Securities Class Action are without merit and intends to defend itself vigorously. Outcomes in litigation can be uncertain and it is possible a court may disagree with the Company’s positions. An adverse determination in the Securities Class Action could subject the Company to significant liabilities, which could have a material adverse effect on the Company’s business, financial condition, results of operations and prospects.

Derivative Action

In March 2022, Trung Nguyen filed a shareholder derivative complaint on behalf of nominal defendant Berkeley Lights, Inc., alleging that certain of the Company’s current and former directors and certain of the Company’s current and former senior executives breached their fiduciary duties to the Company. The complaint also alleged that certain of the Company’s current and former directors and former senior executives used material, non-public information to improperly profit from the sale of Company stock, and that certain of the Company’s current and

Berkeley Lights, Inc.

Notes to Condensed Consolidated Financial Statements

(Unaudited)

former senior executives owe the Company contribution for violations of sections 10(b) and 21D of the Securities Exchange Act of 1934.

The Company is not currently involved in any other claims or legal actions, nor is management aware of any potential claims or legal actions, for which the ultimate disposition could have a material adverse effect on the Company’s financial position, results of operations, or liquidity.

No provision has been made for litigation because the Company believes that it is not probable that a liability had been incurred as of June 30, 2022.

Product Warranty

The Company provides a 13-month assurance-type warranty, generally beginning on the shipment date, on its platforms and chip consumables. The table below represents the activity in the product warranty accrual included in accrued expenses and other current liabilities on the condensed consolidated balance sheets (in thousands):


	Three months ended June 30,				Six months ended June 30,
	2022		2021		2022		2021
Balance, beginning of period	$	914	$	1,268	$	1,085	$	1,271
Adjustments to existing warranties	(185)		(148)		(430)		(366)
Provision for new warranties	179		242		342		617
Settlement of pre-existing warranties	(156)		(172)		(245)		(332)
Balance, end of period	$	752	$	1,190	$	752	$	1,190

(15)Net Loss Attributable to Common Stockholders Per Share

Potentially issuable shares of common stock include shares issuable upon the exercise of outstanding employee stock option awards. Awards granted with performance conditions are excluded from the shares used to compute diluted earnings per share until the performance conditions associated with the awards are met.

The following table sets forth the computation of basic and diluted earnings per common share (in thousands, except share and per share data):


	Three months ended June 30,				Six months ended June 30,
	2022		2021		2022		2021

Numerator
Net loss attributable to common stockholders, basic and diluted	$	(25,747)	$	(18,154)	$	(47,173)	$	(33,589)
Denominator
Weighted-average shares used to compute net income per share, basic and diluted	67,985,664		66,790,755		67,842,372		66,029,307
Net loss per share
Net loss per share attributable to common stockholders, basic and diluted	$	(0.38)	$	(0.27)	$	(0.70)	$	(0.51)

Berkeley Lights, Inc.

Notes to Condensed Consolidated Financial Statements

(Unaudited)

Since the Company was in a loss position for all periods presented, basic net loss per share attributable to common stockholders is the same as diluted net loss per share attributable to common stockholders, as the inclusion of all potential shares of common stock outstanding would have been anti-dilutive. The following weighted-average common stock equivalents were excluded from the calculation of diluted net loss per share attributable to common stockholders for the periods presented as they had an anti-dilutive effect:


	Three and six months ended June 30,
	2022	2021

Options to purchase common stock	7,750,612	7,619,929
Restricted stock units	4,241,025	470,985
Total	11,991,637	8,090,914

(16)Segments

Operating segments are defined as components of an enterprise about which separate financial information is available that is evaluated regularly by the chief operating decision maker, or decision-making group, in deciding how to allocate resources and in assessing performance. The Company’s chief operating decision maker is its Chief Executive Officer. The Company has one business activity and there are no segment managers who are held accountable for operations. Accordingly, the Company has one operating segment. The Company’s principal operations and decision-making functions are located in the United States.

The following table provides the Company’s revenues by geographical market based on the location where the services were provided or to which product was shipped (in thousands):


	Three months ended June 30,				Six months ended June 30,
	2022		2021		2022		2021

North America	$	9,891	$	8,874	$	23,585	$	16,236
Asia Pacific (1)	7,201		9,268		12,236		17,699
Europe	2,058		1,108		3,535		3,943
	$	19,150	$	19,250	$	39,356	$	37,878

(1) Asia Pacific includes Australia.

As of June 30, 2022 and December 31, 2021, substantially all of the Company’s long-lived assets were located in the United States.

(17)Subsequent Events

On July 21, 2022, to improve efficiency and manage operating expenses the Company terminated the employment of approximately 12% of total full-time employees. The Company estimates it will incur severance and employee-related restructuring costs of approximately $1.1 million related to this activity, substantially all of which the Company expects to incur in the third quarter of 2022.

Item 2. Management’s Discussion and Analysis of Financial Condition and Results of Operations.

Special Note Regarding Forward-Looking Statements

This Quarterly Report on Form 10-Q contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 concerning our business, operations and financial performance and condition, as well as our plans, objectives and expectations for our business, operations and financial performance and condition. Any statements contained herein that are not statements of historical facts may be deemed to be forward-looking statements. In some cases, you can identify forward-looking statements by terminology such as “aim,” “anticipate,” “assume,” “believe,” “contemplate,” “continue,” “could,” “due,” “estimate,” “expect,” “goal,” “intend,” “may,” “objective,” “plan,” “predict,” “potential,” “positioned,” “seek,” “should,” “target,” “will,” “would” and other similar expressions that are predictions of or indicate future events and future trends, or the negative of these terms or other comparable terminology, although not all forward-looking statements contain these words.

Forward-looking statements are based on management’s current expectations, estimates, forecasts and projections about our business and the industry in which we operate, and management’s beliefs and assumptions are not guarantees of future performance or development and involve known and unknown risks, uncertainties and other factors that are in some cases beyond our control. As a result, any or all of our forward-looking statements in this Quarterly Report on Form 10-Q may turn out to be inaccurate. Furthermore, if the forward-looking statements prove to be inaccurate, the inaccuracy may be material. In light of the significant uncertainties in these forward-looking statements, you should not regard these statements as a representation or warranty by us or any other person that we will achieve our objectives and plans in any specified time frame, or at all.

In addition, statements that “we believe” and similar statements reflect our beliefs and opinions on the relevant subject. These statements are based upon information available to us as of the date of this Quarterly Report on Form 10-Q, and while we believe such information forms a reasonable basis for such statements, such information may be limited or incomplete, and our statements should not be read to indicate that we have conducted an exhaustive inquiry into, or review of, all potentially available relevant information. These statements are inherently uncertain and investors are cautioned not to unduly rely upon these statements.

You should read the following discussion of our financial condition and results of operations in conjunction with our unaudited condensed financial statements and the related notes and other financial information included elsewhere in this Quarterly Report on Form 10-Q and our audited consolidated financial statements and notes thereto and management’s discussion and analysis of financial condition and results of operations for the fiscal year ended December 31, 2021 included in the Annual Report on Form 10-K and filed with the Securities and Exchange Commission (the “SEC”) on February 28, 2022 (the “Annual Report”). Our actual results could differ materially from those anticipated in these forward-looking statements as a result of various factors, including those discussed in Item 1A. “Risk Factors” of our Annual Report, elsewhere in this Quarterly Report on Form 10-Q, and our other reports filed with the SEC.

Overview

Berkeley Lights is a leading Digital Cell Biology company focused on enabling and accelerating the rapid development and commercialization of biotherapeutics and other cell-based products. The Berkeley Lights Platform captures deep phenotypic, functional and genotypic information for thousands of single cells in parallel and can also deliver the live biology customers desire in the form of the best cells. This is a new way to capture and interpret the qualitative language of biology and translate it into single-cell specific digital information, referred to as Digital Cell Biology. We currently focus on enabling the large and rapidly growing markets of antibody therapeutics, cell therapy, gene therapy, agricultural biology and synthetic biology with our platform.

The Berkeley Lights Platform can be used to characterize the performance of cells relevant to the desired cell-based product early in the discovery process and then connect this phenotypic data to the genetic code for each cell. In contrast, current genomic technologies find sequences first and fail to deliver the functional information early in the process. Performing functional validation early means letting poorly performing cells fail early while rapidly advancing the best candidates forward, before incurring significant research and development expense. Our platform repeats this process of fail and advance many times throughout the process, delivering the best cells for what we believe will deliver the best product.

Our platform is a fully integrated, end-to-end solution, comprised of advanced automation systems, proprietary consumables, including our OptoSelect chips and reagent kits, and advanced application and workflow software. Customers load onto our system their live cell samples, as well as media and reagents, then the cells are imported onto our OptoSelect chips where integrated workflows are performed to assess specific cell functions and attributes. Our platform captures and delivers rich single-cell data to find the best cells. Our platform leverages our proprietary OptoElectro Positioning (“OEP”) technology, which enables deterministic positioning of living single cells and other micro-objects using light. OEP is a core technology of our platform and allows for a high level of control over live single cells or other micro-objects throughout the functional characterization process.

Our commercial workflows, each of which are distinct offerings, are made up of four modules we call Import, Culture, Assay and Export. These modules can be adapted, interchanged and deployed with a variety of single-cell assays to address specific applications and a variety of cell types. We believe this versatility facilitates rapid development of new workflow offerings and virtually unlimited workflow commercialization opportunities. We have developed and will continue to develop and commercialize proprietary workflows across large markets by leveraging existing workflows and assays. Over time, our goal is to enable customers to standardize many of their processes on our platform utilizing our workflows. We believe we are the only company commercializing a platform that can do this in a scalable way.

We commercially launched our platform in December of 2016, which included the Beacon system and the alpha version of our Opto Cell Line Development 1.0 workflow, targeted to the antibody therapeutics market. From the initial launch of our platform through June 30, 2022, we have commercially launched ten workflows. In June of 2019, we launched our desktop Lightning system targeted for assay development and lower throughput workflows, and in early 2020 we launched our Culture Station instrument.

We focus a substantial portion of our resources on platform, workflow and assay development, as well as on business development and sales and marketing. Our research and development efforts are primarily focused on developing new workflows and assay capabilities, as well as new advanced systems and OptoSelect chips and reagent kits, to meet both our customers’ needs and to address new markets.

During 2022, we validated the unique capability on our platform to select and retrieve high-value stable producer cell lines that will improve the cost and therapeutically relevant yields for manufacturing Adeno-associated virus (“AAV”)-based gene therapies, which we believe represents a significant return on investment opportunity in the near term. As such, we intend to dedicate a significant number of our resources towards development of this workflow in the second half of 2022 and in 2023.

We generally outsource all of our production manufacturing. Design work, prototyping and pilot manufacturing are performed in-house before outsourcing to third party contract manufacturers. Our outsourced production strategy is intended to drive cost leverage and scale, and avoid the high capital outlays and fixed costs related to constructing and operating a manufacturing facility. The contract manufacturers of our systems are located in the United States. Contract manufacturers for reagent kits and OptoSelect chip components are located in the United States, Asia and Europe. Certain of our suppliers of components and materials are single source suppliers. We perform final manufacture and assembly steps of our OptoSelect chips in-house.

Our customer base includes several of the largest biopharmaceutical companies in the world, as well as biotechnology companies, leading contract research organizations, synthetic biology companies and academic institutions. While we have seen significant growth in our customer and installed base, we believe we are still in the very early stages of platform adoption, with the majority our historical revenue derived from early adopters of our technology for research and development purposes.

We have financed our operations primarily from the issuance and sale of equity securities, borrowings under our long-term debt agreement, and to a lesser extent from cash generated by product and service sales. On July 21, 2020, we closed our initial public offering (the “IPO”), in which we sold 9,315,000 shares of common stock (which included 1,215,000 shares that were sold pursuant to the full exercise of the IPO underwriters’ option to purchase additional shares) at a price to the public of $22.00 per share. We received aggregate net proceeds of $187.9 million after deducting, offering costs, underwriting discounts and commissions of $17.0 million.

Since our inception in 2011, we have incurred net losses in each year. Our net losses were $25.7 million and $18.2 million for the three months ended June 30, 2022 and 2021, respectively and $47.2 million and $33.6 million for the six months ended June 30, 2022 and 2021, respectively. As of June 30, 2022, we had an accumulated deficit of $310.8 million and cash, cash equivalents and marketable securities totaling $152.4 million. We expect to continue to incur significant expenses and operating losses for the foreseeable future.

Certain of our financial results and other key operational developments for the three and six months ended June 30, 2022 include the following:

•Total revenue for the three and six months ended June 30, 2022 was $19.2 million and $39.4 million, respectively, compared to $19.3 million and $37.9 million for the same periods in 2021, respectively.

•Gross profit in absolute dollars slightly increased during the three months ended June 30, 2022 compared to the same period in 2021. Gross margin increased to 67% from 66% during the three months ended June 30, 2022 compared to the same period in 2021. Gross profit increased in absolute dollars during the six months ended June 30, 2022 compared to the same period in 2021. Gross margin for the six months ended June 30, 2022 increased to 68% compared to 66% for the six months ended June 30, 2021.

Recent Trends

There are multiple broad based factors impacting our business:

1.First, the COVID-19 pandemic has had, and continues to have, a significant impact around the world, prompting governments and businesses to take unprecedented measures, including temporary closures of businesses, quarantines and shelter in place orders.

2.Global and domestic supply chains and the timely availability of raw materials and products have been and may continue to be materially disrupted by quarantines, factory slowdowns or shutdowns, border closings and travel restrictions resulting from the COVID-19 pandemic.

3.The COVID-19 pandemic, in addition to other macroeconomic factors including the war between Ukraine and Russia as well as political instability in the United States, has resulted in unfavorable global economic conditions including increased inflation and interest rates.

Our business has been impacted and will continue to be impacted by the above factors, by among other things, the following:

In the second half of 2022, certain of our strategic partnership and services engagements are ending. Coupled with our focus on the AAV opportunity discussed above, we expect revenue from strategic partnership and services agreements to decline in the near term.

In addition, pandemic related lockdowns in China throughout the first quarter of 2022 adversely impacted the operation of our office in Shanghai, in which the majority of our employees in our Asia Pacific region reside. While the city-wide lockdowns were lifted in the second quarter of 2022, localized lockdowns still remain.

To date, our production, shipping and customer service functions have remained operational to maintain a continuous supply of products both to our customers and for our internal research and development activities. Any manufacturing supply interruption of materials could adversely affect our ability to conduct ongoing and future activities. We continue to closely monitor global supply issues around materials, parts and components, including plastics and integrated circuit chips, and we have not experienced any material supply issue to date.

The ultimate impact of COVID-19 and unfavorable economic conditions on our operations and financial performance in future periods remains uncertain and will depend on many factors outside our control, including the timing, extent, trajectory, and duration of the pandemic as well as the magnitude of any potential recession and related government actions to prevent and manage these issues, all of which are uncertain and cannot be predicted. While the overall impact of COVID-19 and unfavorable economic conditions is impossible to measure, they have resulted in, and may continue to result in, significant disruption of global financial markets, reducing our ability to access capital, which could in the future negatively affect our liquidity and, ultimately our business and operations. Refer to Part I, Item 1A of our Annual Report under the heading “Risk Factors” for more information.

Components of results of operations

Revenue

Our revenue consists of both product revenue and service revenue, which is generated through the following revenue streams: (i) direct platform sales, (ii) recurring revenue, and (iii) strategic partnerships and services agreements. Sales of advanced automation systems, recurring revenue from consumables, workflow subscription agreements, and workflow licenses are defined as product revenue, and revenue from strategic partnership and services agreements and extended or enhanced warranty contracts, feasibility studies and platform support are defined as service revenue in our consolidated results of operations. We launched our Tech Access subscription model in June 2021.

The following tables provide an overview of our revenue streams and how we report revenue in our consolidated statements of operations (in thousands):

Income Statement Classification

Product or Service sold

Revenue Stream

Product revenue

Sale of advanced automation system (Beacon and Lightning system, Culture Station)

Direct platform sales

Software

Direct platform sales

Fixed term sales-type lease arrangements with qualified customers

Direct platform sales

Annual renewable workflow licenses, quarterly workflow subscriptions, annual or multi-year subscriptions arrangements (e.g. TechAccess)

Recurring revenue

Consumables and reagent kits (e.g. OptoSelect chips)

Recurring revenue

Service revenue

Strategic partnerships, joint development and collaboration agreements where we provide services for development of new workflows, cells or organism types

Strategic partnerships and services

Application support, installation and training

Direct platform sales

Fixed fee extended warranty and service programs

Recurring revenue

We renamed our joint development and partnership offering to strategic partnerships and services in the fourth quarter of 2021.


	Three months ended June 30, 2022						Six months ended June 30, 2022
(in thousands)	Product		Service		Total		Product		Service		Total
Direct platform sales	$	6,226	$	200	$	6,426	$	12,973	$	857	$	13,830
Recurring revenue	3,242		2,687		5,929		6,269		5,103		11,372
Strategic partnerships and services	—		6,795		6,795		—		14,154		14,154
Total revenue	$	9,468	$	9,682	$	19,150	$	19,242	$	20,114	$	39,356


	Three months ended June 30, 2021						Six months ended June 30, 2021
(in thousands)	Product		Service		Total		Product		Service		Total
Direct platform sales	$	10,717	$	672	$	11,389	$	21,303	$	1,202	$	22,505
Recurring revenue	2,304		1,642		3,946		5,251		3,089		8,340
Strategic partnerships and services	—		3,915		3,915		—		7,033		7,033
Total revenue	$	13,021	$	6,229	$	19,250	$	26,554	$	11,324	$	37,878

The following tables provide information by revenue stream for the periods presented:


	Three months ended June 30,
(in thousands, except percentages)	2022		2021		Change
Direct platform sales	$	6,426	$	11,389	$	(4,963)	(44)	%
Recurring revenue	5,929		3,946		1,983		50	%
Strategic partnerships and services	6,795		3,915		2,880		74	%
Total revenue	$	19,150	$	19,250	$	(100)	(1)	%


	Six months ended June 30,
(in thousands, except percentages)	2022		2021		Change
Direct platform sales	$	13,830	$	22,505	$	(8,675)	(39)	%
Recurring revenue	11,372		8,340		3,032		36	%
Strategic partnerships and services	14,154		7,033		7,121		101	%
Total revenue	$	39,356	$	37,878	$	1,478	4	%

Costs of sales, gross profit and gross margin

Product cost of sales. Cost of sales associated with our products primarily consists of manufacturing related costs incurred in the production process, including personnel and related costs, costs of component materials, labor and overhead, packaging and delivery costs and allocated costs, including facilities and information technology. These costs also include the costs associated with the standard assurance-type product warranty provided on our platforms, which are recorded at the time of sale.

Service cost of sales. Cost of sales associated with our services primarily consists of personnel and related costs, expenses related to the development of customized platforms and workflows, feasibility studies on our platforms and service and warranty costs to support our customers. We maintain continuous efforts to increase reliability and uptime of our advanced automation systems.

Gross profit and gross margin. Gross profit is calculated as revenue less cost of sales. Gross margin is gross profit expressed as a percentage of revenue. Our gross profit in future periods will depend on a variety of factors, including: market conditions that may impact our pricing; sales mix among platform access options, including the regional mix of sales; sales mix changes among consumables, advanced automation systems and services; product mix changes between established products and new products; excess and obsolete inventories; our cost structure for manufacturing operations relative to volume; and product warranty obligations. We expect cost of sales to increase in absolute dollars in future periods as our revenue grows, and as we plan to hire additional employees to support our manufacturing, operations, service and support organizations.

Gross profit was $12.9 million and $26.8 million for the three and six months ended June 30, 2022, respectively. Gross profit was $12.7 million and $25.2 million for the three and six months ended June 30, 2021, respectively.

Operating expenses

Research and development. Research and development costs primarily consist of salaries, benefits, incentive compensation, stock-based compensation, laboratory supplies, materials expenses and allocated facilities and IT costs for employees and contractors engaged in research and product development. We expense all research and development costs in the period in which they are incurred.

We plan to continue to invest in our research and development efforts, including hiring additional employees, to enhance existing products and develop new products. As a result, we expect that our research and development expenses will continue to increase in absolute dollars in future periods. We expect these expenses to vary from period to period as a percentage of revenue.

General and administrative. Our general and administrative expenses primarily consist of salaries, benefits and stock-based compensation costs for employees in our executive, accounting and finance, legal and human resource functions, as well as professional services fees, such as consulting, audit, tax and legal fees, general corporate costs and allocated overhead expenses. We expect that our general and administrative expenses will continue to increase in absolute dollars, primarily due to increased headcount to support anticipated growth in the business and due to incremental costs associated with operating as a public company. We expect these expenses to vary from period to period as a percentage of revenue.

Sales and marketing. Our sales and marketing expenses consist primarily of salaries, benefits, sales commissions and stock-based compensation costs for employees within our commercial sales functions, as well as marketing, travel expenses and allocated facilities and IT costs. We expect our sales and marketing expenses to increase in absolute dollars as we expand our commercial sales, marketing and business development teams, increase our presence globally and increase marketing activities to drive awareness and adoption of our platform. While these expenses may vary from period to period as a percentage of revenue, we expect these expenses to increase as a percent of sales in the short-term as we continue to grow our commercial organization to support anticipated growth in the business.

Other income (expense)

Interest expense. Interest expense consists primarily of interest related to borrowings under our debt obligations.

Interest income. Interest income primarily consists of interest earned on our cash and cash equivalents which are invested in cash deposits and in money market funds.

Other income (expense), net. Other income (expense), net consists primarily of foreign currency exchange gains and losses. Foreign currency exchange gains and losses relate to transactions and asset and liability balances denominated in currencies other than the U.S. dollar, primarily related to our operations in the United Kingdom and China. We expect our foreign currency gains and losses to continue to fluctuate in the future due to changes in foreign currency exchange rates.

Provision for income taxes

Our provision for income taxes consists primarily of foreign taxes and state taxes in the United States. The Company maintains a full valuation allowance on its deferred tax assets and intends to do so until there is sufficient evidence to support the reversal of all or some portion of these allowances. As we expand the scale and scope of our international business activities, any changes in taxation of such activities may increase our overall provision for income taxes in the future.

Results of operations

The following tables set forth our results of operations for the periods presented:


	Three months ended June 30,				Six months ended June 30,
(in thousands)	2022		2021		2022		2021
Revenue:
Product revenue	$	9,468	$	13,021	$	19,242	$	26,554
Service revenue	9,682		6,229		20,114		11,324
Total revenue	19,150		19,250		39,356		37,878
Cost of sales:
Product cost of sales	2,614		3,332		5,309		7,035
Service cost of sales	3,610		3,190		7,294		5,664
Total cost of sales (1)	6,224		6,522		12,603		12,699
Gross profit	12,926		12,728		26,753		25,179
Operating expenses:
Research and development (1)	18,178		13,535		35,751		26,562
General and administrative (1)	13,024		11,725		24,740		20,692
Sales and marketing (1)	7,271		5,317		13,082		10,923
Total operating expenses	38,473		30,577		73,573		58,177
Loss from operations	(25,547)		(17,849)		(46,820)		(32,998)
Other income (expense):
Interest expense	(227)		(356)		(451)		(710)
Interest income	53		43		87		109
Other income (expense), net	(22)		34		35		53
Loss before income taxes	(25,743)		(18,128)		(47,149)		(33,546)
Provision for income taxes	4		26		24		43
Net loss	$	(25,747)	$	(18,154)	$	(47,173)	$	(33,589)

(1)Amounts include stock-based compensation as follows:


	Three months ended June 30,				Six months ended June 30,
(in thousands)	2022		2021		2022		2021
Cost of sales	$	68	$	63	$	119	$	105
Research and development	2,292		1,599		3,873		2,660
General and administrative	2,318		2,497		4,529		3,869
Sales and marketing	1,887		1,470		3,437		3,489
Total stock-based compensation expense	$	6,565	$	5,629	$	11,958	$	10,123

Comparison of the three and six months ended June 30, 2022 and 2021

Revenue


	Three months ended June 30,				Three month change				Six months ended June 30,				Six month change
(in thousands, except percentages)	2022		2021		Amount		%		2022		2021		Amount		%
Product revenue	$	9,468	$	13,021	$	(3,553)	(27	%)	$	19,242	$	26,554	$	(7,312)	(28	%)
Service revenue	9,682		6,229		3,453		55	%	20,114		11,324		$	8,790	78	%
Total revenue	$	19,150	$	19,250	$	(100)	(1)	%	$	39,356	$	37,878	$	1,478	4	%

Product revenue decreased by $3.6 million, or 27%, for the three months ended June 30, 2022, compared to the three months ended June 30, 2021. The decrease was primarily due to lower platform and system sales of $4.5 million, including sales-type lease arrangements, partially offset by an increase of $0.9 million in consumable sales driven by a higher installed platform base and an increase of $0.1 million in subscription arrangements and related revenue. During the three months ended June 30, 2022 we placed five platforms, compared to seven platforms placed during the three months ended June 30, 2021.

Service revenue increased by $3.5 million, or 55%, for the three months ended June 30, 2022, compared to the three months ended June 30, 2021. The increase was primarily driven by higher revenue associated with strategic partnerships and services agreements of $2.9 million, due to work performed on agreements signed in the second half of 2021, as well as an increase in service warranty and application support agreements of $0.6 million, which resulted from a higher installed platform base.

Product revenue decreased by $7.3 million, or 28%, for the six months ended June 30, 2022, compared to the six months ended June 30, 2021. The decrease was primarily due to lower platform and system sales of $8.3 million, including sales-type lease arrangements, partially offset by an increase of $0.8 million in consumable sales due to a higher installed platform base and an increase of $0.2 million in subscription arrangements and related revenue. During the six months ended June 30, 2022 we placed nine platforms, compared to seventeen platforms placed during the six months ended June 30, 2021.

Service revenue increased by $8.8 million, or 78%, for the six months ended June 30, 2022, compared to the six months ended June 30, 2021. The increase was primarily driven by higher revenue associated with strategic partnerships and services agreements of $7.1 million as well as an increase in service warranty and application support agreements of $1.7 million, which resulted from a higher installed platform base.

Cost of sales, gross profit and gross margin


	Three months ended June 30,				Three month change				Six months ended June 30,				Six month change
(in thousands, except percentages)	2022		2021		Amount		%		2022		2021		Amount		%
Product cost of sales	$	2,614	$	3,332	$	(718)	(22	%)	$	5,309	$	7,035	$	(1,726)	(25	%)
Service cost of sales	3,610		3,190		420		13	%	7,294		5,664		1,630		29	%
Total cost of sales	$	6,224	$	6,522	$	(298)	(5	%)	$	12,603	$	12,699	$	(96)	(1	%)
Gross profit	$12,926		$12,728		$	198	2	%	$	26,753	$	25,179	$	1,574	6	%
Gross margin	67 %		66 %						68 %		66 %

Product cost of sales for the three months ended June 30, 2022 decreased by $0.7 million, or 22%, compared to the three months ended June 30, 2021 and was due to the decline in product revenue and the favorable impact of settlements and adjustments to our warranty liabilities.

Service cost of sales increased by $0.4 million, or 13%, by during the three months ended June 30, 2022, compared to the three months ended June 30, 2021 due to increased costs for our strategic partnerships and services agreements.

Product cost of sales for the six months ended June 30, 2022 decreased by $1.7 million, or 25%, compared to the six months ended June 30. 2022. The decrease was primarily driven by lower revenue from our platform and system sales, including sales-type lease arrangements and the favorable impact of settlements and adjustments to our warranty liabilities.

Service cost of sales for the six months ended June 30, 2022 increased by $1.6 million, or 29%, compared to the six months ended June 30, 2021 primarily as a result of higher costs associated with our extended warranty plans and increased costs associated with our strategic partnerships and services agreements.

Gross profit increased by $0.2 million, or 2%, during the three months ended June 30, 2022, compared to the three months ended June 30, 2021. Gross margin increased to 67% from 66% for the three months ended June 30, 2022, compared to the three months ended June 30, 2021.

Gross profit increased by $1.6 million, or 6%, during the six months ended June 30, 2022, compared to the six months ended June 30, 2021. Gross margin increased to 68% from 66% for the six months ended June 30, 2022, compared to the six months ended June 30, 2021.

Gross profit for both the three months and six months ended June 30, 2022 were positively impacted by the fact that the strategic partnerships and services agreements we entered into in 2021 have a higher margin than our previous strategic partnership and services agreements, of which the largest was our collaboration agreement with Ginkgo Bioworks, Inc.

Operating Expenses

Research and development


	Three months ended June 30,				Three month change				Six months ended June 30,				Six month change
(in thousands, except percentages)	2022		2021		Amount		%		2022		2021		Amount		%
Research and development	$	18,178	$	13,535	$	4,643	34	%	$	35,751	$	26,562	$	9,189	35 %

Research and development expense increased by $4.6 million, or 34%, and by $9.2 million, or 35%, respectively, for the three and six months ended June 30, 2022, compared to the three and six months ended June, 30, 2021. The increases were primarily due to increased personnel-related expenses, including a $0.7 million and $1.2 million increase in stock-based compensation in each of the periods, respectively, as well as increases in other costs, including testing and qualification materials and other costs related to various projects to develop and improve systems, workflows, consumables and assays.

General and administrative


	Three months ended June 30,				Three month change				Six months ended June 30,				Six month change
(in thousands, except percentages)	2022		2021		Amount		%		2022		2021		Amount		%
General and administrative	$	13,024	$	11,725	$	1,299	11	%	$	24,740	$	20,692	$	4,048	20 %

General and administrative expense increased by $1.3 million, or 11%, and by $4.0 million, or 20%, respectively, for the three and six months ended June 30, 2022, compared to the three and six months ended June 30, 2021. The increases were primarily due to increased personnel-related expenses, including an increase (decrease) in stock-based compensation expense of ($0.2 million) and $0.7 million for the three and six months ended June 30, 2022, respectively, and increased costs to improve our information processes and other infrastructure required for a public company, partially offset by a decrease in outside legal fees related to patent litigation.

Sales and marketing


	Three months ended June 30,				Three month change				Six months ended June 30,				Six month change
(in thousands, except percentages)	2022		2021		Amount		%		2022		2021		Amount		%
Sales and marketing	$	7,271	$	5,317	$	1,954	37	%	$	13,082	$	10,923	$	2,159	20 %

Sales and marketing expense increased by $2.0 million, or 37%, and by $2.2 million, or 20%, respectively, for the three and six months ended June 30, 2022, compared to the three and six months ended June 30, 2021. The increase was primarily due to increased personnel-related expenses, including an increase (decrease) in stock-based compensation expense of $0.4 million and ($0.1 million) for the three and six months ended June 30, 2022, respectively, and also due to an overall increase in marketing, advertising and other sales costs.

Interest expense


	Three months ended June 30,				Three month change				Six months ended June 30,				Six month change
(in thousands, except percentages)	2022		2021		Amount		%		2022		2021		Amount		%
Interest expense	$	227	$	356	$	(129)	(36	%)	$	451	$	710	$	(259)	(36	%)

Interest expense decreased by $0.1 million, or 36%, and $0.3 million, or 36%, respectively, for the three and six months ended June 30, 2022, compared to the three and six months ended June 30, 2021, as a result of refinancing our loan from East West Bank, which now carries a lower interest rate.

Interest income


	Three months ended June 30,				Three month change				Six months ended June 30,				Six month change
(in thousands, except percentages)	2022		2021		Amount		%		2022		2021		Amount		%
Interest income	$	53	$	43	$	10	23	%	$	87	$	109	$	(22)	(20	%)

Interest income was flat for the three and six months ended June 30, 2022, compared to the three and six months ended June 30, 2021. We generate interest income through our cash and short-term deposits, and also through short-term available-for-sale marketable securities, which we invested during the latter part of the second quarter of 2022.

Other income (expense), net


	Three months ended June 30,				Three month change				Six months ended June 30,				Six month change
(in thousands, except percentages)	2022		2021		Amount		%		2022		2021		Amount		%
Other income (expense), net	$	(22)	$	34	$	(56)	(165	%)	$	35	$	53	$	(18)	(34	%)

Other income for the three and six months ended June 30, 2022 and 2021 was mainly comprised of foreign exchange gains and losses and other miscellaneous income and expense items.

Liquidity and capital resources

As of June 30, 2022, we had approximately $152.4 million in cash and cash equivalents and marketable securities which were primarily held in U.S. short-term bank deposit accounts and other investment grade short-term available-for-sale debt securities. Restricted cash at December 31, 2021 of $0.3 million served as collateral for our corporate credit card program. This amount is no longer restricted as of June 30, 2022. We have generated negative cash flows from operations since inception through June 30, 2022.

We expect to incur additional operating losses in the foreseeable future as we continue to invest in the research and development of our product offerings, commercialize and launch platforms, and expand into new markets. Our future capital requirements will depend on many factors including our revenue growth rate, research and development efforts, the timing and extent of additional capital expenditures to invest in existing and new facilities as well as our manufacturing operations, the expansion of sales and marketing and the introduction of

new products. Our future capital needs may also depend upon the impacts of the COVID-19 pandemic. We have and may in the future enter into arrangements to acquire or invest in businesses, services and technologies, and any such acquisitions or investments could significantly increase our capital needs.

Based on our current business plan, we believe our existing cash and cash equivalents and anticipated cash flows from operations will be sufficient to meet our working capital and capital expenditure needs over at least the next 12 months.

Sources of liquidity

Since our inception, we have financed our operations primarily from the issuance and sale of our equity securities, borrowings under long-term debt agreements, and to a lesser extent, cash generated by product and service sales. In July 2020, we completed our IPO, resulting in the receipt of aggregate proceeds of $187.9 million, net of offering costs, underwriter discounts and commissions of $17.0 million.

East West Bank Loan and Security Agreement

On May 23, 2018, we entered into a Loan and Security Agreement with East West Bank (“EWB”) providing us the ability to borrow up to $20.0 million. The loan facility was fully drawn as of May 23, 2018.

On June 30, 2021, we entered into an Amended and Restated Loan and Security Agreement (the “Agreement”) with EWB. Pursuant to the Agreement, EWB provided a $20.0 million term loan (the “Term Loan”) which was used to refinance the term loan outstanding under the Loan and Security Agreement dated May 23, 2018. The Term Loan matures in 48 months and bears interest at a fixed rate of 4.17%. The Term Loan has an initial interest-only period of 24 months, which can be extended to up to 36 months based on the achievement of certain liquidity measures, and can be pre-paid without penalty at any time.

The Agreement grants EWB a security interest in and liens on all of our assets, excluding intellectual property, which is subject to a double negative pledge. In addition, certain other terms of the original agreements as previously in effect were amended by the Agreement, including certain financial covenants. The Amended and Restated Loan and Security Agreement was accounted for as a debt modification and we capitalized incremental debt issuance costs.

Furthermore, the Agreement also provided the Company with a new $10.0 million revolving credit line (the “Revolving Line”), which bears interest on the outstanding daily balance thereof of 0.70% above the Prime Rate (as defined in the Agreement). No amount was outstanding under the Revolving Line as at June 30, 2022.

We were in compliance with all covenants under the Agreement as of June 30, 2022.

Cash flows

The following table summarizes our cash flows for the periods presented:


	Six months ended June 30,
(in thousands)	2022		2021
Net cash (used in) provided by:
Operating activities	$	(20,588)	$	(24,095)
Investing activities	(16,130)		(4,382)
Financing activities	1,376		10,146
Net decrease in cash and cash equivalents and restricted cash	$	(35,342)	$	(18,331)

Operating activities

Net cash used in operating activities of $20.6 million for the six months ended June 30, 2022 was attributable to a net loss of $47.2 million, partially offset by non-cash adjustments of $18.7 million, mainly consisting of stock-based compensation and depreciation expense, and a net cash inflow from changes in our operating assets and liabilities of $7.8 million, primarily due to a decrease in our accounts receivable.

Net cash used in operating activities of $24.1 million for the six months ended June 30, 2021 was attributable to a net loss of $33.6 million and cash outflows from changes in our net operating assets and liabilities of $4.7 million, partially offset by $14.2 million of non-cash charges, primarily related to stock-based compensation and depreciation and amortization. Cash outflow from our net operating assets and liabilities was primarily due to an increase in inventories resulting from an increase in raw materials and finished goods, an increase in accounts receivable due to an increase in revenue and the timing of invoicing, partially offset by an increase in deferred revenue and accounts payable due to the timing of advanced billings and revenue recognition as well as the timing of vendor invoicing and related payments.

Investing activities

Net cash used in investing activities was $16.1 million during the six months ended June 30, 2022, compared to $4.4 million during the six months ended June 30, 2021. The increase was primarily driven by the purchase of $9.4 million of available-for-sale marketable securities during the second quarter of 2022 and $6.8 million of purchases of property, plant and equipment. Capital expenditures for the first six months of 2022 include the expansion of our BioFoundry laboratory operations to support current and planned programs as well as leasehold improvements related to our new offices in Boston, Massachusetts.

Net cash used in investing activities was $4.4 million for the six months ended June 30, 2021 and related to capital expenditures for the expansion of our BioFoundry laboratory. Capital expenditures for the six months ended June 30, 2021, exclude a $3.8 million non-cash transfer of Beacons that were purchased into inventory and later transferred to property and equipment. As a result of the growth of our BioFoundry operations, including growth in the number of Beacons used to fulfill strategic partnerships and services agreements, beginning in the third quarter of 2021, Beacons that at inception are planned to be used in our BioFoundry operations are categorized as “Purchase of property and equipment.”

Financing activities

Net cash provided by financing activities was $1.4 million during the six months ended June 30, 2022, compared to $10.1 million for the six months ended June 30, 2021. Net cash provided by financing activities during the six months ended June 30, 2022 and 2021 primarily related to proceeds received from the issuance of common stock upon exercise of stock options as well as proceeds received related to the issuance of common stock under our employee stock purchase plan.

Concentration of credit risk

Most of the Company’s customers are located in the United States and Asia Pacific. For the three months ended June 30, 2022, three customers accounted for 20%, 11%, and 10% of revenue. For the six months ended June 30. 2022, three customers accounted for 16%, 11% and 10% of revenue. For the three months ended June 30, 2021, three customers accounted for 27%, 18%, and 11% of revenue. For the six months ended June 30, 2021, three customers accounted for 14%, 11% and 10% of revenue.

As of June 30, 2022, three customers comprised 27%, 12%, and 11% of accounts receivable. As of December 31, 2021, three customers accounted for 15%, 11% and 11% of accounts receivable.

Contractual obligations and commitments

There have been no material changes to our contractual obligations as of June 30, 2022, as compared to those disclosed in the Annual Report on Form 10-K for the year ended December 31, 2021.

Off-balance sheet arrangements

We do not have, and did not have during the periods presented, any off-balance sheet financing arrangements or any relationships with unconsolidated entities or financial partnerships, including entities sometimes referred to as structured finance or special purpose entities, that were established for the purpose of facilitating off-balance sheet arrangements or other contractually narrow or limited purposes.

Critical accounting policies and estimates

We have prepared our condensed consolidated financial statements in accordance with United States generally accepted accounting principles. Our preparation of these condensed consolidated financial statements requires us to make estimates, assumptions and judgments that affect the reported amounts of assets, liabilities, revenue, expenses and related disclosures. We evaluate our estimates and judgments on an ongoing basis. We base our estimates on historical experience and on various other factors that we believe are reasonable under the circumstances, the results of which form the basis for making judgments about the carrying value of assets and liabilities that are not readily apparent from other sources. Actual results could therefore differ materially from these estimates under different assumptions or conditions.

There have been no significant changes in our critical accounting policies and estimates as compared to the critical accounting policies and estimates disclosed in the section titled “Management’s Discussion and Analysis of Financial Condition and Operations” included in our Annual Report on Form 10-K for the year ended December 31, 2021 filed with the SEC on February 28, 2022, with the following exceptions.

Stock-Based Compensation

We maintain an incentive compensation plan under which stock options and restricted stock units (“RSU”) are granted to employees and non-employee consultants.

Stock-based compensation expense is based on the grant date fair value of the award. We determine the fair value of RSUs based on the closing value of our stock price listed on the Nasdaq at the date of the grant.

We estimate the fair value of the majority of stock option awards on the grant date using the Black-Scholes option-pricing model. For option awards that include a goal tied to the Company share price (i.e. a market condition) we use a Monte Carlo simulation to estimate the fair value.

For performance stock options and awards not initially assessed as probable of achievement, we record a cumulative adjustment to compensation expense in the period we change our determination that a performance condition becomes probable of being achieved. We cease recognition of compensation expense in any periods

where we determine the attainment of a performance condition is no longer probable. If the performance goals are determined to be improbable, any previously recognized compensation expense is reversed.

Item 3. Quantitative and Qualitative Disclosures about Market Risk.

Interest rate risk

Customer financing exposure. We are indirectly exposed to interest rate risk because many of our customers depend on debt financings to purchase our platforms and systems. An increase in interest rates could make it challenging for our customers to obtain the capital necessary to make such purchases on favorable terms, or at all. Such factors could reduce demand or lower the price we can charge for our platforms and systems, thereby reducing our net sales and gross profit.

Bank deposit, money market and marketable securities exposure. As of June 30, 2022, we had cash and cash equivalents and available-for-sale marketable debt securities, of $152.4 million, which consisted primarily of money market funds, bank deposits and debt instruments of high quality corporate issuers and the U.S. government. The primary objective of our investments is to facilitating liquidity and capital preservation. None of our investments are held for trading purposes. These short-term investments generate interest income at rates typically between 1% and 3%. A hypothetical 100 basis point decrease in interest rates would have no material effect on our interest income and financial results.

Foreign currency risk

Through June 30, 2022, we did not generate any revenue denominated in foreign currencies. While we incur certain expenses in foreign currencies, especially related to our foreign offices, the impact of changes in exchange rates has been immaterial as of June 30, 2022 for these expenses. As we expand our presence in international markets, to the extent we are required to enter into agreements denominated in a currency other than the U.S. dollar, our results of operations and cash flows may increasingly be subject to fluctuations due to changes in foreign currency exchange rates and may be adversely affected in the future due to changes in foreign exchange rates. To date, we have not entered into any hedging arrangements with respect to foreign currency risk. As our international operations grow, we will continue to reassess our approach to manage our risk relating to fluctuations in currency rates.

Item 4. Controls and Procedures.

Evaluation of Disclosure Controls and Procedures

We carried out an evaluation, under the supervision and with the participation of management, including our principal executive officer and principal financial officer, of the effectiveness of our “disclosure controls and procedures” as defined in Rules 13a-15(e) and 15d-15(e) under the Securities Exchange Act of 1934, as amended (the “Exchange Act”). Based on that evaluation, our principal executive officer and principal financial officer concluded that as of June 30, 2022 our disclosure controls and procedures were effective at a reasonable assurance level to ensure that information required to be disclosed by us in reports that we file or submit under the Exchange Act is recorded, processed, summarized, and reported within the time periods specified in SEC rules and forms, and that such information is accumulated and communicated to our management, including our principal executive officer and principal financial officer, as appropriate, to allow timely decisions regarding required disclosure.

Changes in Internal Control over Financial Reporting

We also carried out an evaluation, under the supervision and with the participation of management, including our principal executive officer and principal financial officer, of our “internal control over financial reporting” to determine whether any changes in our internal control over financial reporting occurred during the three months ended June 30, 2022 that materially affected, or are reasonably likely to materially affect, our internal control over financial reporting. Based on that evaluation, there were no such changes in our internal control over financial reporting that occurred during the three months ended June 30, 2022.

Limitations on the Effectiveness of Controls

Control systems, no matter how well designed and operated, can provide only reasonable, not absolute, assurance that the control systems’ objectives are being met. Further, the design of any system of controls must reflect the fact that there are resource constraints, and the benefits of all controls must be considered relative to their costs. Because of the inherent limitations in all control systems, no evaluation of controls can provide absolute assurance that all control issues and instances of fraud, if any, within our Company have been detected. These inherent limitations include the realities that judgments in decision-making can be faulty and that breakdowns can occur because of error or mistake. Control systems can also be circumvented by the individual acts of some persons, by collusion of two or more people, or by management override of the controls. The design of any system of controls is also based in part upon certain assumptions about the likelihood of future events, and there can be no assurance that any design will succeed in achieving its stated goals under all potential future conditions. Over time, controls may become inadequate because of changes in conditions or deterioration in the degree of compliance with policies or procedures.

Part II. OTHER INFORMATION.

Item 1. Legal Proceedings.

See Note 14, “Commitments and Contingencies” under the heading “Legal Proceedings” in the Notes to the Unaudited Condensed Consolidated Financial Statements included in Part 1, Item 1 of this Quarterly Report on Form 10-Q for legal proceedings and related matters.

Item 1A. Risk Factors.

Factors that could cause or contribute to differences in our future financial and operating results include those discussed in the risk factors set forth in our Annual Report and below in this Quarterly Report:

Our revenue under our customer sales engagements, program and service agreements and strategic partnerships and services for any particular period can be difficult to forecast.

Because of the complexities and long sales cycles inherent in our business, including, in particular, certain customer feasibility study agreements and collaboration and development agreements, it is difficult to predict the timing of a customer’s purchase of our system and of the performance and completion of milestones under our customer and collaboration agreements. As a result, our revenue for any particular period can be difficult to forecast, especially in light of the challenging and inconsistent global macroeconomic environment and related market uncertainty. Our revenue may grow at a slower rate than in past periods or even decline on a year-over-year basis. For example, under our collaboration agreement with Ginkgo Bioworks, or Ginkgo, the agreement provides that we are eligible to receive certain minimum annual payments from Ginkgo for purchases and services, as well as milestone payments upon the achievement of certain development and regulatory milestones resulting from the use of certain of our proprietary workflows. However, we are unable to predict with precision whether and the extent to which Ginkgo will exceed the minimum annual payments under our agreement, or the timing of the achievement of any milestones under the agreement, if achieved at all, even though we maintain discussions on such matters. In some cases, the timing and likelihood of payments to us under these agreements is dependent on our customers’ successful utilization of our products and workflows, which is outside of our control. In the near term, we expect revenue from our strategic partnerships and services engagements to decline; more generally, our operating results could vary materially from quarter to quarter from our forecasts due to the foregoing uncertainties.

The risk factors included in our Annual Report and in this Quarterly Report are not the only risks that we face. Additional risks not presently known to us or that we do not currently consider significant may also have an adverse effect on the Company. If any of the risks actually occur, our business, results of operations, cash flows or financial condition could suffer.

Except as provided above, there have been no material changes to the risk factors set forth in the Annual Report.

Item 2. Unregistered Sales of Equity Securities and Use of Proceeds.

Sale of Unregistered Securities

There were no unregistered sales of the Company's equity securities during the three months ended June 30, 2022.

Use of Proceeds from our IPO

On July 21, 2020, we closed our IPO, in which we issued and sold 9,315,000 shares of our common stock, including the full exercise of the underwriters’ over-allotment option, at a public offering price of $22.00 per share for aggregate offering proceeds of $204.9 million. All of the shares of common stock issued and sold in the

offering were registered under the Securities Act of 1933, as amended, pursuant to a registration statement on Form S-1 (File No. 333-239487), which was declared effective by the SEC on July 16, 2020.

Cash used since the IPO is described elsewhere in the “Management’s Discussion and Analysis of Financial Condition and Results of Operations” section of our periodic reports filed with the SEC. As of the date of this filing, there has been no material change in the planned use of proceeds from our IPO as described in the final prospectus for our IPO dated July 16, 2020 filed with the SEC on July 17, 2020.

Item 3. Defaults Upon Senior Securities.

Not applicable.

Item 4. Mine Safety Disclosures.

Not applicable.

Item 5. Other Information.

None.

Item 6. Exhibits.

The following exhibits are filed with this Quarterly Report on Form 10-Q:

Incorporated by Reference

Exhibit Number

Exhibit Title

Form

File No.

Exhibit

Filing Date

Filed Herewith

3.1

Amended and Restated Certificate of Incorporation of Berkeley Lights, Inc.

8-K

001-39388

3.1

7/21/2020

3.2

Amended and Restated Bylaws of Berkeley Lights, Inc.

8-K

001-39388

3.2

7/21/2020

10.5

Employment Offer Letter by and between Berkeley Lights , Inc. and Mehul Joshi

31.1

Certification of Principal Executive Officer Pursuant to Section 302 of the Sarbanes-Oxley Act of 2002.

31.2

Certification of Principal Financial Officer Pursuant to Section 302 of the Sarbanes-Oxley Act of 2002.

32.1*

Certification of Principal Executive Officer Pursuant to Section 906 of the Sarbanes-Oxley Act of 2002.

32.2*

Certification of Principal Financial Officer Pursuant to Section 906 of the Sarbanes-Oxley Act of 2002.

101.INS

XBRL Instance Document.

101.SCH

XBRL Taxonomy Extension Schema Document.

101.CAL

XBRL Taxonomy Extension Calculation Linkbase Document

101.DEF

XBRL Taxonomy Extension Definition Linkbase Document.

101.LAB

XBRL Taxonomy Extension Label Linkbase Document.

101.PRE

XBRL Taxonomy Extension Presentation Linkbase Document.

104

Cover Page Interactive Data File - formatted in Inline XBRL and included as Exhibit 101

*This exhibit shall not be deemed “filed” for purposes of Section 18 of the Exchange Act or otherwise subject to the liabilities of that section, nor shall it be deemed incorporated by reference in any filing under the Securities Act or the Exchange Act, whether made before or after the date hereof and irrespective of any general incorporation language in such filings

Signatures

Pursuant to the requirements of the Securities and Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf of the undersigned thereunto duly authorized.

Berkeley Lights, Inc.


Date: August 9, 2022	By:	/s/ J. Paul McClaskey
		J. Paul McClaskey Chief Accounting Officer (Authorized Signatory and Chief Accounting Officer)