AIM ImmunoTech Inc. - Quarter Report: 2007 June (Form 10-Q)
UNITED
      STATES
    SECURITIES
      AND EXCHANGE COMMISSION
    WASHINGTON,
      D.C. 20549
    FORM
      10-Q
    Quarterly
      Report Pursuant to Section 13 or 15(d)
    of
      the
      Securities Exchange Act of 1934
    For
      the
      Quarterly Period Ended June 30, 2007
    Commission
      File Number: 0-27072
    HEMISPHERx
      BIOPHARMA, INC. 
    (Exact
      name of registrant as specified in its charter)
    | 
               Delaware 
             | 
            
               52-0845822
                 
             | 
          
| 
               (State
                or other jurisdiction of  
             | 
            
               (I.R.S.
                Employer 
             | 
          
| 
               incorporation
                or organization)  
             | 
            
               Identification
                No.) 
             | 
          
1617
      JFK Boulevard, Suite 660, Philadelphia, PA 19103 
    (Address
      of principal executive offices) (Zip Code)
    (215)
      988-0080 
    (Registrant's
      telephone number, including area code)
    Not
      Applicable 
    (Former
      name, former address and former fiscal year, if changed since last
      report)
    Indicate
      by check mark whether the registrant (1) has filed all reports required to
      be
      filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during
      the
      preceding 12 months (or for such shorter period that the registrant was required
      to file such reports), and (2) has been subject to such filing requirements
      for
      the past 90 days. x
      Yes o No
    Indicate
      by check mark whether the registrant is a large accelerated filer, an
      accelerated filer, or a non-accelerated filer. See definition of accelerated
      filer and large accelerated filer in Rule 12b-2 of the Exchange Act. (Check
      one): 
    o
Large
      accelerated
      filer           x    
 Accelerated
      file    
o
Non-accelerated
      filer
    Indicate
      by check mark whether the registrant is a shell company (as defined in Rule
      12b-2 of the Exchange Act).o
 Yes       x
      No
    72,826,971
      shares of common stock were issued and outstanding as of August 7, 2007.
    1
        PART
      I -
      FINANCIAL INFORMATION
    ITEM
      1:
      Financial Statements
    HEMISPHERx
      BIOPHARMA, INC. AND SUBSIDIARIES
    Consolidated
      Balance Sheets
    (in
      thousands,
      except
      share and per share data)
    | 
               December
                31, 
             | 
            
               June
                30, 
             | 
            ||||||
| 
               2006 
             | 
            
               2007 
             | 
            ||||||
| 
               (unaudited) 
             | 
            |||||||
| 
               ASSETS 
             | 
            |||||||
| 
               Current
                assets: 
             | 
            |||||||
| 
               Cash
                and cash equivalents  
             | 
            
               $ 
             | 
            
               3,646 
             | 
            
               $ 
             | 
            
               6,989 
             | 
            |||
| 
               Short
                term investments (Note 4) 
             | 
            
               18,375 
             | 
            
               14,670 
             | 
            |||||
| 
               Inventory,
                net  
             | 
            
               957 
             | 
            
               598 
             | 
            |||||
| 
               Accounts
                and other receivables, net of reserves of $1 and $1, respectively
                 
             | 
            
               93 
             | 
            
               83 
             | 
            |||||
| 
               Prepaid
                expenses and other current assets 
             | 
            
               168 
             | 
            
               159 
             | 
            |||||
| 
               Total
                current assets 
             | 
            
               23,239 
             | 
            
               22,499 
             | 
            |||||
| 
               Property
                and equipment, net 
             | 
            
               4,720 
             | 
            
               4,672 
             | 
            |||||
| 
               Patent
                and trademark rights, net 
             | 
            
               857 
             | 
            
               885 
             | 
            |||||
| 
               Construction
                in progress  
             | 
            
               624 
             | 
            
               896 
             | 
            |||||
| 
               Royalty
                interest 
             | 
            
               601 
             | 
            
               573 
             | 
            |||||
| 
               Deferred
                financing costs  
             | 
            
               38 
             | 
            
               - 
             | 
            |||||
| 
               Advance
                receivable (Note 5) 
             | 
            
               1,300 
             | 
            
               - 
             | 
            |||||
| 
               Other
                assets 
             | 
            
               52 
             | 
            
               52 
             | 
            |||||
| 
               Total
                assets 
             | 
            
               $ 
             | 
            
               31,431 
             | 
            
               $ 
             | 
            
               29,577 
             | 
            |||
| 
               LIABILITIES
                AND STOCKHOLDERS' EQUITY 
             | 
            |||||||
| 
               Current
                liabilities: 
             | 
            |||||||
| 
               Accounts
                payable 
             | 
            
               $ 
             | 
            
               1,548 
             | 
            
               $ 
             | 
            
               1,733 
             | 
            |||
| 
               Accrued
                expenses  
             | 
            
               1,261 
             | 
            
               1,123 
             | 
            |||||
| 
               Current
                portion of long-term debt (Note 5) 
             | 
            
               3,871 
             | 
            
               - 
             | 
            |||||
| 
               Total
                current liabilities 
             | 
            
               6,680 
             | 
            
               2,856 
             | 
            |||||
| 
               Commitments
                and contingencies 
             | 
            |||||||
| 
               Stockholders'
                equity: 
             | 
            |||||||
| 
               Preferred
                stock, par value $0.01 per share, authorized
                5,000,000; issued and outstanding; none
                 
             | 
            
               - 
             | 
            
               - 
             | 
            |||||
| 
               Common
                stock, par value $0.01 per share, authorized
                200,000,000 shares; issued and outstanding
                66,816,764 and 72,723,813 respectively 
             | 
            
               67 
             | 
            
               73 
             | 
            |||||
| 
               Additional
                paid-in capital 
             | 
            
               191,689 
             | 
            
               202,408 
             | 
            |||||
| 
               Accumulated
                other comprehensive income 
             | 
            
               46 
             | 
            
               316 
             | 
            |||||
| 
               Accumulated
                deficit 
             | 
            
               (167,051 
             | 
            
               ) 
             | 
            
               (176,076 
             | 
            
               ) 
             | 
          |||
| 
               Total
                stockholders' equity 
             | 
            
               24,751 
             | 
            
               26,721 
             | 
            |||||
| 
               Total
                liabilities and stockholders' equity 
             | 
            
               $ 
             | 
            
               31,431 
             | 
            
               $ 
             | 
            
               29,577 
             | 
            |||
See
      accompanying notes to condensed consolidated financial statements. 
    2
        HEMISPHERX
      BIOPHARMA, INC. AND SUBSIDIARIES
    Consolidated
      Statements of Operations
    (in
      thousands, except share and per share data)
    (Unaudited)
    | Three months ended June 30, | |||||||
| 
               2006 
             | 
            
               2007 
             | 
            ||||||
| 
               Revenues: 
             | 
            |||||||
| 
               Sales
                of product net 
             | 
            
               $ 
             | 
            
               197 
             | 
            
               $ 
             | 
            
               196 
             | 
            |||
| 
               Clinical
                treatment programs 
             | 
            
               50 
             | 
            
               38 
             | 
            |||||
| 
               Total
                revenues 
             | 
            
               247 
             | 
            
               234 
             | 
            |||||
| 
               Costs
                and expenses: 
             | 
            |||||||
| 
               Production/cost
                of goods sold 
             | 
            
               398 
             | 
            
               315 
             | 
            |||||
| 
               Research
                and development 
             | 
            
               2,588 
             | 
            
               2,534 
             | 
            |||||
| 
               General
                and administrative 
             | 
            
               2,086 
             | 
            
               1,543 
             | 
            |||||
| 
               Total
                costs and expenses 
             | 
            
               5,072 
             | 
            
               4,392 
             | 
            |||||
| 
               Interest
                and other income  
             | 
            
               205 
             | 
            
               416 
             | 
            |||||
| 
               Interest
                expense 
             | 
            
               (326 
             | 
            
               ) 
             | 
            
               (44 
             | 
            
               ) 
             | 
          |||
| 
               Financing
                costs (Note 5)  
             | 
            
               (135 
             | 
            
               ) 
             | 
            
               (139 
             | 
            
               ) 
             | 
          |||
| 
               Net
                loss  
             | 
            
               $ 
             | 
            
               (5,081 
             | 
            
               ) 
             | 
            
               $ 
             | 
            
               (3,925 
             | 
            
               ) 
             | 
          |
| 
               Basic
                and diluted loss per share (Note 2) 
             | 
            
               $ 
             | 
            
               (.08 
             | 
            
               ) 
             | 
            
               $ 
             | 
            
               (.05 
             | 
            
               ) 
             | 
          |
| 
               Weighted
                average shares outstanding, basic and diluted 
             | 
            
               64,033,333 
             | 
            
               72,192,229 
             | 
            |||||
See
      accompanying notes to consolidated financial statements.
    3
        HEMISPHERX
      BIOPHARMA, INC. AND SUBSIDIARIES
    Consolidated
      Statements of Operations
    (in
      thousands, except share and per share data)
    (Unaudited)
    | Six months ended June 30, | |||||||
| 
               2006 
             | 
            
               2007 
             | 
            ||||||
| 
               Revenues: 
             | 
            |||||||
| 
               Sales
                of product net 
             | 
            
               $ 
             | 
            
               380 
             | 
            
               $ 
             | 
            
               416 
             | 
            |||
| 
               Clinical
                treatment programs 
             | 
            
               103 
             | 
            
               73 
             | 
            |||||
| 
               Total
                revenues 
             | 
            
               483 
             | 
            
               489 
             | 
            |||||
| 
               Costs
                and expenses: 
             | 
            |||||||
| 
               Production/cost
                of goods sold 
             | 
            
               697 
             | 
            
               551 
             | 
            |||||
| 
               Research
                and development 
             | 
            
               5,018 
             | 
            
               5,710 
             | 
            |||||
| 
               General
                and administrative 
             | 
            
               5,178 
             | 
            
               3,326 
             | 
            |||||
| 
               Total
                costs and expenses 
             | 
            
               10,893 
             | 
            
               9,587 
             | 
            |||||
| 
               Interest
                and other income  
             | 
            
               160 
             | 
            
               465 
             | 
            |||||
| 
               Interest
                expense 
             | 
            
               (410 
             | 
            
               ) 
             | 
            
               (115 
             | 
            
               ) 
             | 
          |||
| 
               Financing
                costs (Note 5)  
             | 
            
               (340 
             | 
            
               ) 
             | 
            
               (277 
             | 
            
               ) 
             | 
          |||
| 
               Net
                loss  
             | 
            
               $ 
             | 
            
               (11,000 
             | 
            
               ) 
             | 
            
               $ 
             | 
            
               (9,025 
             | 
            
               ) 
             | 
          |
| 
               Basic
                and diluted loss per share (Note 2) 
             | 
            
               $ 
             | 
            
               (.18 
             | 
            
               ) 
             | 
            
               $ 
             | 
            
               (.13 
             | 
            
               ) 
             | 
          |
| 
               Weighted
                average shares outstanding, basic and diluted 
             | 
            
               60,132,309 
             | 
            
               70,518,087 
             | 
            |||||
See
      accompanying notes to consolidated financial statements.
    4
        HEMISPHERx
      BIOPHARMA, INC. AND SUBSIDIARIES
    Consolidated
      Statements of Changes in Stockholders' Equity and Comprehensive loss
     (in
      thousands except share data)
    (Unaudited)
    | 
               Common 
              stock 
              shares 
             | 
            
               Common
                Stock $.001 Par
                Value 
             | 
            
               Additional
                paid-in
                capital 
             | 
            
               Accumulated
                other comprehensive
                income  
             | 
            
               Accumulated
                deficit 
             | 
            
               Total
                stockholders’ equity 
             | 
            ||||||||||||||
| 
               Balance
                at December 31, 2006 
             | 
            
               66,816,764 
             | 
            
               $ 
             | 
            
               67 
             | 
            
               $ 
             | 
            
               191,689 
             | 
            
               $ 
             | 
            
               46 
             | 
            
               $ 
             | 
            
               (167,051 
             | 
            
               ) 
             | 
            
               $ 
             | 
            
               24,751 
             | 
            |||||||
| 
               Interest
                payments 
             | 
            
               64,769 
             | 
            
               - 
             | 
            
               124 
             | 
            
               - 
             | 
            
               - 
             | 
            
               124 
             | 
            |||||||||||||
| 
               Private
                placement, net of issuance costs 
             | 
            
               5,750,530 
             | 
            
               6 
             | 
            
               10,264 
             | 
            
               - 
             | 
            
               - 
             | 
            
               10,270 
             | 
            |||||||||||||
| 
               Stock
                issued for settlement of accounts payable 
             | 
            
               91,750 
             | 
            
               - 
             | 
            
               167 
             | 
            
               - 
             | 
            
               - 
             | 
            
               167 
             | 
            |||||||||||||
| 
               Equity
                based compensation 
             | 
            
               - 
             | 
            
               - 
             | 
            
               164 
             | 
            
               - 
             | 
            
               - 
             | 
            
               164 
             | 
            |||||||||||||
| 
               Net
                comprehensive income (loss)  
             | 
            
               - 
             | 
            
               -
                 
             | 
            
               - 
             | 
            
               270 
             | 
            
               (9,025 
             | 
            
               ) 
             | 
            
               (8,755 
             | 
            
               ) 
             | 
          |||||||||||
| 
               Balance
                at June 30, 2007 
             | 
            
               72,723,813 
             | 
            
               $ 
             | 
            
               73 
             | 
            
               $ 
             | 
            
               202,408 
             | 
            
               $ 
             | 
            
               316 
             | 
            
               $ 
             | 
            
               (176,076 
             | 
            
               ) 
             | 
            
               $ 
             | 
            
               26,721 
             | 
            |||||||
See
      accompanying notes to consolidated financial statements.
    5
        HEMISPHERx
      BIOPHARMA, INC. AND SUBSIDIARIES
    Consolidated
      Statements of Cash Flows
    For
      the
      Six Months Ended June 30, 2006 and 2007
    (in
      thousands)
    (Unaudited)
| 
               2006 
             | 
            
                2007 
             | 
            ||||||
| 
               Cash
                flows from operating activities: 
             | 
            |||||||
| 
               Net
                loss  
             | 
            
               $ 
             | 
            
               (11,000 
             | 
            
               ) 
             | 
            
               $ 
             | 
            
               (9,025 
             | 
            
               ) 
             | 
          |
| 
               Adjustments
                to reconcile net loss to net cash used in operating
                activities: 
             | 
            |||||||
| 
               Depreciation
                of property and 
              equipment
                 
             | 
            
               70 
             | 
            
               123
                 
             | 
            |||||
| 
               Amortization
                of patent and trademark
                rights, and royalty interest 
             | 
            
               56 
             | 
            
               83 
             | 
            |||||
| 
               Financing
                cost related to debt discounts  
             | 
            
               340 
             | 
            
               277
                 
             | 
            |||||
| 
               Equity
                based compensation 
             | 
            
               2,263 
             | 
            
               164
                 
             | 
            |||||
| 
               Common
                stock issued in payment of interest expense 
             | 
            
               101 
             | 
            
               115 
             | 
            |||||
| 
               Changes
                in assets and liabilities: 
             | 
            |||||||
| 
               Inventory 
             | 
            
               497 
             | 
            
               359 
             | 
            |||||
| 
               Accounts
                and other receivables 
             | 
            
               (93 
             | 
            
               ) 
             | 
            
               (154 
             | 
            
               ) 
             | 
          |||
| 
               Prepaid
                expenses and other 
              current
                assets 
             | 
            
               26 
             | 
            
               9
                 
             | 
            |||||
| 
               Accounts
                payable 
             | 
            
               937 
             | 
            
               353 
             | 
            |||||
| 
               Accrued
                expenses 
             | 
            
               484
                 
             | 
            
               (139 
             | 
            
               ) 
             | 
          ||||
| 
               Net
                cash used in operating 
              activities 
             | 
            
               $ 
             | 
            
               (6,319 
             | 
            
               ) 
             | 
            
               $ 
             | 
            
               (7,835 
             | 
            
               ) 
             | 
          |
| 
               Cash
                flows from investing activities: 
             | 
            |||||||
| 
               Purchase
                of property plant and 
              equipment 
             | 
            
               $ 
             | 
            
               (1,508 
             | 
            
               ) 
             | 
            
               $ 
             | 
            
               (75 
             | 
            
               ) 
             | 
          |
| 
               Additions
                to patent and trademark 
              rights 
             | 
            
               (36 
             | 
            
               ) 
             | 
            
               (82 
             | 
            
               ) 
             | 
          |||
| 
               Maturity
                of short term 
              investments 
             | 
            
               12,548 
             | 
            
               6,778 
             | 
            |||||
| 
               Purchase
                of short term investments 
             | 
            
               (18,884 
             | 
            
               ) 
             | 
            
               (2,803 
             | 
            
               ) 
             | 
          |||
| 
               Construction
                in Progress  
             | 
            
               275 
             | 
            
               (272 
             | 
            
               ) 
             | 
          ||||
| 
               Net
                cash (used in) provided by investing activities 
             | 
            
               $ 
             | 
            
               (7,605 
             | 
            
               ) 
             | 
            
               $ 
             | 
            
               3,546 
             | 
            ||
6
        HEMISPHERX
      BIOPHARMA, INC. AND SUBSIDIARIES
    Consolidated
      Statements of Cash Flows (Continued)
    For
      the
      Six Months Ended June 30, 2006 and 2007
    (in
      thousands)
    (Unaudited)
    | 
               2006 
             | 
            
               2007 
             | 
            ||||||
| 
               Cash
                flows from financing activities: 
             | 
            |||||||
| 
               Payment
                of long-term debt 
             | 
            
               $ 
             | 
            
               - 
             | 
            
               $ 
             | 
            
               (4,102 
             | 
            
               ) 
             | 
          ||
| 
               Collection
                of advance receivable 
             | 
            
               - 
             | 
            
               1,464 
             | 
            |||||
| 
               Proceeds
                from exercise of stock warrants 
             | 
            
               672 
             | 
            
               - 
             | 
            |||||
| 
               Proceeds
                from sale of stock, net of issuance costs 
             | 
            
               11,980 
             | 
            
               10,270 
             | 
            |||||
| 
               Net
                cash provided by financing 
              activities 
             | 
            
               $ 
             | 
            
               12,652 
             | 
            
               $ 
             | 
            
               7,632 
             | 
            |||
| 
               Net
                (decrease) increase in cash and cash equivalents 
             | 
            
               (1,272 
             | 
            
               ) 
             | 
            
               3,343
                 
             | 
            ||||
| 
               | 
            |||||||
| 
               Cash
                and cash equivalents at beginning of period 
             | 
            
               3,827 
             | 
            
               3,646
                 
             | 
            |||||
| 
               Cash
                and cash equivalents at end of period 
             | 
            
               $ 
             | 
            
               2,555 
             | 
            
               $ 
             | 
            
               6,989 
             | 
            |||
| 
               Supplemental
                disclosures of non-cash investing and financing cash flow
                information: 
             | 
            |||||||
| 
               Issuance
                of common stock for 
              accounts
                payable and accrued 
              expenses
                 
             | 
            
               $ 
             | 
            
               146 
             | 
            
               $ 
             | 
            
               167 
             | 
            |||
| 
               Issuance
                of common stock for    
              debt
                conversion and debt 
              payments 
             | 
            
               $ 
             | 
            
               834 
             | 
            
               $ 
             | 
            
               - 
             | 
            |||
| 
               Unrealized
                gains on investments 
             | 
            
               $ 
             | 
            
               79 
             | 
            
               $ 
             | 
            
               316 
             | 
            |||
See
      accompanying notes to consolidated financial statements.
7
        HEMISPHERx
      BIOPHARMA, INC. AND SUBSIDIARIES
    NOTES
      TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS
    NOTE
      1: BASIS OF PRESENTATION
    The
      consolidated financial statements include the financial statements of Hemispherx
      Biopharma, Inc. and its wholly-owned subsidiaries. The Company has three
      domestic subsidiaries BioPro Corp., BioAegean Corp. and Core Biotech Corp.,
      all
      of which are incorporated in Delaware and are dormant. The Company’s foreign
      subsidiary, Hemispherx Biopharma Europe N.V./S.A., established in Belgium in
      1998, has limited or no activity. All significant intercompany balances and
      transactions have been eliminated in consolidation.
    In
      the
      opinion of management, all adjustments necessary for a fair presenta-tion of
      such consolidated financial statements have been included. Such adjust-ments
      consist of normal recurring items. Interim results are not necessarily
      indicative of results for a full year. 
    The
      interim consolidated financial statements and notes thereto are presented as
      permitted by the Securities and Exchange Commission (SEC), and do not contain
      certain information which will be included in our annual consolidated financial
      statements and notes thereto. 
    These
      consolidated financial statements should be read in conjunction with our
      consolidated financial statements included in our annual report on Form 10-K
      for the
      year
      ended December 31, 2006, as filed with the SEC on March
      19, 2007.
    NOTE
      2: NET
      LOSS PER SHARE 
     
      Basic
      and diluted net loss per share is computed using the weighted average number
      of
      shares of common stock outstanding during the period. Equivalent common shares,
      consisting of stock options and warrants including the Company’s convertible
      debentures, which amounted to 30,005,360 and 17,530,415 shares, are excluded
      from the calculation of diluted net loss per share for the six months ended
      June
      30, 2006 and 2007, respectively, since their effect is antidilutive.
    NOTE
      3: EQUITY BASED COMPENSATION
    The
      fair
      value of each option award is estimated on the date of grant using a
      Black-Scholes option valuation model. Expected volatility is based on the
      historical volatility of the price of the Company’s stock. The risk-free
      interest rate is based on U.S. Treasury issues with a term equal to the expected
      life of the option. The Company uses historical data to estimate expected
      dividend yield, expected life and forfeiture rates. The fair values of the
      options granted, were estimated based on the following weighted average
      assumptions:
    | 
               Six
                Months Ended June 30, 
             | 
          ||||
| 
               2006 
             | 
            
               2007 
             | 
          |||
| 
               Risk-free
                interest rate 
             | 
            
               4.3%
                - 4.6% 
             | 
            
               4.46
                - 4.90% 
             | 
          ||
| 
               Expected
                dividend yield 
             | 
            
               - 
             | 
            
               - 
             | 
          ||
| 
               Expected
                lives 
             | 
            
               2.5-5
                yrs 
             | 
            
               5
                yrs 
             | 
          ||
| 
               Expected
                volatility 
             | 
            
               72.1%-79.3% 
             | 
            
               76.74
                - 77.57% 
             | 
          ||
| 
               Weighted
                average grant date fair value of options and warrants issued
                 
             | 
            
               $2,503,000 
             | 
            
               | 
            
               $140,037 
             | 
          |
8
        Stock
      option activity during the six months ended June 30, 2007, is as
      follows:
    Stock
      option activity for employees:
    | 
               Number
                of  
              Options
                 
             | 
            
               Weighted
                 
              Average
                Exercise  
              Price
                 
             | 
            
               Weighted
                 
              Average
                 
              Remaining
                 
              Contractual
                 
              Term
                (Years)  
             | 
            
               Aggregate
                Intrinsic  
              Value
                 
             | 
            ||||||||||
| 
               Outstanding
                December 31, 2006 
             | 
            
               2,001,969
                 
             | 
            
               $ 
             | 
            
               2.51 
             | 
            
               8.01
                 
             | 
            |||||||||
| 
               Options
                granted 
             | 
            
               64,120 
             | 
            
               2.14 
             | 
            
               9.50 
             | 
            ||||||||||
| 
               Options
                forfeited 
             | 
            
               (411 
             | 
            
               ) 
             | 
            
               - 
             | 
            
               - 
             | 
            |||||||||
| 
               Outstanding
                June 30, 2007 
             | 
            
               2,065,678 
             | 
            
               2.50 
             | 
            
               7.85 
             | 
            
               - 
             | 
            |||||||||
| 
               Exercisable
                June 30, 2007 
             | 
            
               1,951,692 
             | 
            
               2.52 
             | 
            
               8.45 
             | 
            
               - 
             | 
            |||||||||
The
      weighted-average grant-date fair value of options granted during the six months
      ended June 30, 2007 was $123,202.
    Unvested
      stock option activity for employees:
    | 
               Number
                of  
              Options
                 
             | 
            
               Weighted
                 
              Average
                Exercise  
              Price
                 
             | 
            
               Average
                 
              Remaining
                 
              Contractual
                 
              Term
                (Years)  
             | 
            
               Aggregate
                Intrinsic  
              Value
                 
             | 
            ||||||||||
| 
               Outstanding
                December 31, 2006 
             | 
            
               113,986
                 
             | 
            
               $ 
             | 
            
               2.26 
             | 
            
               9.05
                 
             | 
            |||||||||
| 
               Options
                granted 
             | 
            
               - 
             | 
            
               - 
             | 
            
               - 
             | 
            ||||||||||
| 
               Options
                forfeited 
             | 
            
               - 
             | 
            
               - 
             | 
            
               - 
             | 
            
               - 
             | 
            |||||||||
| 
               Outstanding
                June 30, 2007 
             | 
            
               113,986 
             | 
            
               $ 
             | 
            
               2.26 
             | 
            
               8.80 
             | 
            
               - 
             | 
            ||||||||
Stock
      option activity for non-employees:
    | 
               Number
                of  
              Options
                 
             | 
            
               Weighted
                 
              Average
                Exercise  
              Price
                 
             | 
            
               Weighted
                 
              Average
                 
              Remaining
                 
              Contractual
                 
              Term
                (Years)
                 
             | 
            
               Aggregate
                Intrinsic  
              Value
                 
             | 
            ||||||||||
| 
               Outstanding
                December 31, 2006 
             | 
            
               1,326,732
                 
             | 
            
               $ 
             | 
            
               2.63 
             | 
            
               8.18
                 
             | 
            |||||||||
| 
               Options
                granted 
             | 
            
               33,750 
             | 
            
               $ 
             | 
            
               2.37 
             | 
            
               9.50 
             | 
            |||||||||
| 
               Options
                forfeited 
             | 
            
               - 
             | 
            
               - 
             | 
            
               - 
             | 
            ||||||||||
| 
               Outstanding
                June 30, 2007 
             | 
            
               1,360,482 
             | 
            
               $ 
             | 
            
               2.63 
             | 
            
               7.95 
             | 
            
               - 
             | 
            ||||||||
| 
               Exercisable
                June 30, 2007 
             | 
            
               1,323,382 
             | 
            
               $ 
             | 
            
               2.64 
             | 
            
               8.35 
             | 
            
               - 
             | 
            ||||||||
The
      weighted-average grant-date fair value of options granted during the six months
      ended June 30, 2007 was $97,870.
    9
        Unvested
      stock option activity for non-employees during the year:
    | 
               Number
                of  
              Options
                 
             | 
            
               Weighted
                 
              Average
                Exercise  
              Price
                 
             | 
            
               Weighted
                 
              Average
                 
              Remaining
                 
              Contractual
                 
              Term
                (Years)  
             | 
            
               Aggregate
                Intrinsic  
              Value
                 
             | 
            ||||||||||
| 
               Outstanding
                December 31, 2006 
             | 
            
               37,100
                 
             | 
            
               $ 
             | 
            
               2.28 
             | 
            
               9.81
                 
             | 
            |||||||||
| 
               Options
                granted 
             | 
            
               -
                 
             | 
            
               -
                 
             | 
            
               -
                 
             | 
            ||||||||||
| 
               Options
                forfeited 
             | 
            
               - 
             | 
            
               - 
             | 
            
               - 
             | 
            
               - 
             | 
            |||||||||
| 
               Outstanding
                June 30, 2007 
             | 
            
               37,100 
             | 
            
               $ 
             | 
            
               2.28 
             | 
            
               9.56 
             | 
            
               -
                 
             | 
            ||||||||
The
      impact on the Company’s results of operations of recording equity based
      compensation for the six months ended June 30, 2007 was to increase general
      and
      administrative expenses by approximately $164,000 and reduce earnings per share
      by $0.00 per basic and diluted share. 
    As
      of
      June 30, 2007, there was $79,000 of unrecognized equity based compensation
      cost
      related to options granted under the Equity Incentive Plan. 
    Note
      4: SHORT TERM INVESTMENTS
    Securities
      classified as available for sale consisted of: 
    | 
               June
                30, 2007 
             | 
            |||||||||||||
| 
               Name
                of Security 
             | 
            
               Cost 
             | 
            
                Market
                Value  
             | 
            
               Unrealized
                Gain (Loss) 
             | 
            
               Maturity
                Date 
             | 
            |||||||||
| 
               General
                Electric Cap Corp 
             | 
            
               $ 
             | 
            
               1,240,000 
             | 
            
               $ 
             | 
            
               1,275,000 
             | 
            
               $ 
             | 
            
               35,000 
             | 
            
               July,
                2007 
             | 
            ||||||
| 
               General
                Electric Cap Serv 
             | 
            
               1,202,000 
             | 
            
               1,233,000 
             | 
            
               31,000
                 
             | 
            
               September,
                2007 
             | 
            |||||||||
| 
               HSBC
                Finance 
             | 
            
               1,000,000 
             | 
            
               1,028,000 
             | 
            
               28,000
                 
             | 
            
               August,
                2007 
             | 
            |||||||||
| 
               FHLMC 
             | 
            
               1,051,000 
             | 
            
               1,078,000 
             | 
            
               27,000
                 
             | 
            
               November,
                2007 
             | 
            |||||||||
| 
               FHLMC 
             | 
            
               960,000 
             | 
            
               985,000 
             | 
            
               25,000
                 
             | 
            
               October,
                2007 
             | 
            |||||||||
| 
               FNMA 
             | 
            
               800,000 
             | 
            
               816,000 
             | 
            
               16,000
                 
             | 
            
               December,
                2007 
             | 
            |||||||||
| 
               FNMA 
             | 
            
               3,000,000 
             | 
            
               3,067,000 
             | 
            
               67,000
                 
             | 
            
               November,
                2007 
             | 
            |||||||||
| 
               FHLMC 
             | 
            
               3,099,000 
             | 
            
               3,163,000 
             | 
            
               64,000
                 
             | 
            
               December,
                2007 
             | 
            |||||||||
| 
               HSBC
                Finance 
             | 
            
               1,004,000 
             | 
            
               1,016,000 
             | 
            
               12,000
                 
             | 
            
               December,
                2007 
             | 
            |||||||||
| 
               General
                Electric 
             | 
            
               998,000 
             | 
            
               1,009,000 
             | 
            
               11,000
                 
             | 
            
               December,
                2007 
             | 
            |||||||||
| 
               $ 
             | 
            
               14,354,000 
             | 
            
               $ 
             | 
            
               14,670,000 
             | 
            
               $ 
             | 
            
               316,000 
             | 
            ||||||||
10
        | 
               December
                31, 2006  
             | 
            |||||||||||||
|  
               Name
                of security 
             | 
            
               Cost  
             | 
            
               Market
                Value  
             | 
            
               Unrealized 
              Gain(Loss)  
             | 
            
               Maturity 
              Date  
             | 
            |||||||||
| 
               | 
            |||||||||||||
| 
               AIG
                Discount Commercial 
             | 
            
               $ 
             | 
            
               972,000 
             | 
            
               $ 
             | 
            
               983,000 
             | 
            
               $ 
             | 
            
               11,000 
             | 
            
               April,
                2007 
             | 
            ||||||
| 
               Natexis
                Banques Popolare 
             | 
            
               969,000 
             | 
            
               979,000 
             | 
            
               10,000 
             | 
            
               May,
                2007 
             | 
            |||||||||
| 
               American
                General Finance 
             | 
            
               965,000 
             | 
            
               974,000 
             | 
            
               9,000 
             | 
            
               June,
                2007 
             | 
            |||||||||
| 
               Daimler
                Chrysler 
             | 
            
               965,000 
             | 
            
               974,000 
             | 
            
               9,000 
             | 
            
               June,
                2007 
             | 
            |||||||||
| 
               LaSalle
                Bank 
             | 
            
               965,000 
             | 
            
               974,000 
             | 
            
               9,000 
             | 
            
               June,
                2007 
             | 
            |||||||||
| 
               General
                Electric  
             | 
            
               1,240,000 
             | 
            
               1,242,000 
             | 
            
               2,000 
             | 
            
               July,
                2007 
             | 
            |||||||||
| 
               HSBC
                Finance 
             | 
            
               1,000,000 
             | 
            
               1,000,000 
             | 
            
               - 
             | 
            
               August,
                2007 
             | 
            |||||||||
| 
               American
                General Finance 
             | 
            
               976,000 
             | 
            
               987,000 
             | 
            
               11,000 
             | 
            
               September,
                2007 
             | 
            |||||||||
| 
               General
                Electric  
             | 
            
               965,000 
             | 
            
               974,000 
             | 
            
               9,000 
             | 
            
               September,
                2007 
             | 
            |||||||||
| 
               General
                Electric  
             | 
            
               1,202,000 
             | 
            
               1,200,000 
             | 
            
               (2,000 
             | 
            
               ) 
             | 
            
               September,
                2007 
             | 
            ||||||||
| 
               FHLMC 
             | 
            
               960,000 
             | 
            
               960,000 
             | 
            
               - 
             | 
            
               October,
                2007 
             | 
            |||||||||
| 
               FHLMC 
             | 
            
               1,051,000 
             | 
            
               1,051,000 
             | 
            
               - 
             | 
            
               November,
                2007 
             | 
            |||||||||
| 
               FNMA 
             | 
            
               3,000,000 
             | 
            
               2,991,000 
             | 
            
               (9,000 
             | 
            
               ) 
             | 
            
               November,
                2007 
             | 
            ||||||||
| 
               FHLMC 
             | 
            
               3,099,000 
             | 
            
               3,086,000 
             | 
            
               (13,000 
             | 
            
               ) 
             | 
            
               December,
                2007 
             | 
            ||||||||
| 
               $ 
             | 
            
               18,329,000 
             | 
            
               $ 
             | 
            
               18,375,000 
             | 
            
               $ 
             | 
            
               46,000 
             | 
            ||||||||
No
      investment securities were pledged to secure public funds at June 30, 2007
      and
      December 31, 2006, respectively.
    The
      table
      below indicates the length of time individual securities have been in a
      continuous unrealized loss position at June 30, 2007 and December 31,
      2006.
    | 
               June
                30, 2007 
             | 
            ||||||||||||||||||||||
| 
               Less
                Than 12 Months  
             | 
            
               12
                Months Or Longer  
             | 
            
                Total
                 
             | 
            ||||||||||||||||||||
| 
               Name
                of
                Security 
             | 
            
               Number
                of
                Securities 
             | 
            
               Fair
                Value  
             | 
            
                Unrealized
                Loss  
             | 
            
               Fair
                Value  
             | 
            
                Unrealized
                Loss  
             | 
            
               Fair
                Value  
             | 
            
                Unrealized
                Loss  
             | 
            |||||||||||||||
| 
               General
                Electric Cap Corp 
             | 
            
               1 
             | 
            
               1,275,000 
             | 
            
               - 
             | 
            
               - 
             | 
            
               - 
             | 
            
               1,275,000 
             | 
            
               - 
             | 
            |||||||||||||||
| 
               General
                Electric Cap Serv 
             | 
            
               1 
             | 
            
               1,233,000 
             | 
            
               - 
             | 
            
               - 
             | 
            
               - 
             | 
            
               1,233,000 
             | 
            
               - 
             | 
            |||||||||||||||
| 
               HSBC
                Finance 
             | 
            
               1 
             | 
            
               1,028,000 
             | 
            
               - 
             | 
            
               - 
             | 
            
               - 
             | 
            
               1,028,000 
             | 
            
               - 
             | 
            |||||||||||||||
| 
               FHLMC 
             | 
            
               1 
             | 
            
               1,078,000 
             | 
            
               - 
             | 
            
               - 
             | 
            
               - 
             | 
            
               1,078,000 
             | 
            
               - 
             | 
            |||||||||||||||
| 
               FHLMC 
             | 
            
               1 
             | 
            
               985,000 
             | 
            
               - 
             | 
            
               - 
             | 
            
               - 
             | 
            
               985,000 
             | 
            
               - 
             | 
            |||||||||||||||
| 
               FNMA 
             | 
            
               1 
             | 
            
               816,000 
             | 
            
               - 
             | 
            
               - 
             | 
            
               - 
             | 
            
               816,000 
             | 
            
               - 
             | 
            |||||||||||||||
| 
               FNMA 
             | 
            
               1 
             | 
            
               3,067,000 
             | 
            
               - 
             | 
            
               - 
             | 
            
               - 
             | 
            
               3,067,000 
             | 
            
               - 
             | 
            |||||||||||||||
| 
               FHLMC 
             | 
            
               1 
             | 
            
               3,163,000 
             | 
            
               - 
             | 
            
               - 
             | 
            
               - 
             | 
            
               3,163,000 
             | 
            
               - 
             | 
            |||||||||||||||
| 
               HSBC
                Finance 
             | 
            
               1 
             | 
            
               1,016,000 
             | 
            
               - 
             | 
            
               - 
             | 
            
               - 
             | 
            
               1,016,000 
             | 
            
               - 
             | 
            |||||||||||||||
| 
               General
                Electric 
             | 
            
               1 
             | 
            
               1,009,000 
             | 
            
               - 
             | 
            
               - 
             | 
            
               - 
             | 
            
               1,009,000 
             | 
            
               - 
             | 
            |||||||||||||||
| 
               Total
                Temporary Impairment 
             | 
            ||||||||||||||||||||||
| 
               Securities 
             | 
            
               10 
             | 
            
               $ 
             | 
            
               14,670,000 
             | 
            
               $ 
             | 
            
               - 
             | 
            
               $ 
             | 
            
               - 
             | 
            
               $ 
             | 
            
               - 
             | 
            
               $ 
             | 
            
               14,670,000 
             | 
            
               $ 
             | 
            
               - 
             | 
            |||||||||
11
        | 
               December
                31, 2006 
             | 
            ||||||||||||||||||||||
| 
               Less
                than 12 months 
             | 
            
               12
                months or longer 
             | 
            
               Total 
             | 
            ||||||||||||||||||||
| 
               Name
                of Security 
             | 
            
               Number
                of Securities 
             | 
            
               Fair
                Value 
             | 
            
               Unrealized
                Loss 
             | 
            
               Fair
                Value 
             | 
            
               Unrealized
                Loss 
             | 
            
               Fair
                Value 
             | 
            
               Unrealized
                Loss 
             | 
            |||||||||||||||
| 
               AIG
                Discount Commercial 
             | 
            
               1 
             | 
            
               $ 
             | 
            
               983,000 
             | 
            
               $ 
             | 
            
               - 
             | 
            
               $ 
             | 
            
               - 
             | 
            
               $ 
             | 
            
               - 
             | 
            
               $ 
             | 
            
               983,000 
             | 
            
               $ 
             | 
            
               - 
             | 
            |||||||||
| 
               Natexis
                Banques Popolare 
             | 
            
               1 
             | 
            
               979,000 
             | 
            
               - 
             | 
            
               - 
             | 
            
               - 
             | 
            
               979,000 
             | 
            
               - 
             | 
            |||||||||||||||
| 
               American
                General Finance 
             | 
            
               1 
             | 
            
               974,000 
             | 
            
               - 
             | 
            
               - 
             | 
            
               - 
             | 
            
               974,000 
             | 
            
               - 
             | 
            |||||||||||||||
| 
               Daimler
                Chrysler 
             | 
            
               1 
             | 
            
               974,000 
             | 
            
               - 
             | 
            
               - 
             | 
            
               - 
             | 
            
               974,000 
             | 
            
               - 
             | 
            |||||||||||||||
| 
               LaSalle
                Bank 
             | 
            
               1 
             | 
            
               974,000 
             | 
            
               - 
             | 
            
               - 
             | 
            
               - 
             | 
            
               974,000 
             | 
            
               - 
             | 
            |||||||||||||||
| 
               General
                Electric 
             | 
            
               1 
             | 
            
               1,242,000 
             | 
            
               - 
             | 
            
               - 
             | 
            
               - 
             | 
            
               1,242,000 
             | 
            
               - 
             | 
            |||||||||||||||
| 
               HSBC
                Finance 
             | 
            
               1 
             | 
            
               1,000,000 
             | 
            
               - 
             | 
            
               - 
             | 
            
               - 
             | 
            
               1,000,000 
             | 
            
               - 
             | 
            |||||||||||||||
| 
               American
                General Finance 
             | 
            
               1 
             | 
            
               987,000 
             | 
            
               - 
             | 
            
               - 
             | 
            
               - 
             | 
            
               987,000 
             | 
            
               - 
             | 
            |||||||||||||||
| 
               General
                Electric 
             | 
            
               1 
             | 
            
               974,000 
             | 
            
               - 
             | 
            
               - 
             | 
            
               - 
             | 
            
               974,000 
             | 
            
               - 
             | 
            |||||||||||||||
| 
               General
                Electric 
             | 
            
               1 
             | 
            
               1,200,000 
             | 
            
               (2,000 
             | 
            
               ) 
             | 
            
               - 
             | 
            
               - 
             | 
            
               1,200,000 
             | 
            
               (2,000 
             | 
            
               ) 
             | 
          |||||||||||||
| 
               FHLMC 
             | 
            
               1 
             | 
            
               960,000 
             | 
            
               - 
             | 
            
               - 
             | 
            
               - 
             | 
            
               960,000 
             | 
            
               - 
             | 
            |||||||||||||||
| 
               FHLMC 
             | 
            
               1 
             | 
            
               1,051,000 
             | 
            
               - 
             | 
            
               - 
             | 
            
               - 
             | 
            
               1,051,000 
             | 
            
               - 
             | 
            |||||||||||||||
| 
               FNMA 
             | 
            
               1 
             | 
            
               2,991,000 
             | 
            
               (9,000 
             | 
            
               ) 
             | 
            
               - 
             | 
            
               - 
             | 
            
               2,991,000 
             | 
            
               (9,000 
             | 
            
               ) 
             | 
          |||||||||||||
| 
               FHLMC 
             | 
            
               1 
             | 
            
               3,086,000 
             | 
            
               (13,000 
             | 
            
               ) 
             | 
            
               - 
             | 
            
               - 
             | 
            
               3,086,000 
             | 
            
               (13,000 
             | 
            
               ) 
             | 
          |||||||||||||
| 
               Total
                Temporary Impairment Securities 
             | 
            
               14 
             | 
            
               $ 
             | 
            
               18,375,000 
             | 
            
               $ 
             | 
            
               (24,000 
             | 
            
               ) 
             | 
            
               $ 
             | 
            
               - 
             | 
            
               $ 
             | 
            
               - 
             | 
            
               $ 
             | 
            
               18,375,000 
             | 
            
               $ 
             | 
            
               (24,000 
             | 
            
               ) 
             | 
          |||||||
In
      management's opinion, the unrealized losses reflect changes in interest rates
      subsequent to the acquisition of specific securities. The Company has the
      ability to hold these securities until maturity or market price recovery.
      Management believes that the unrealized losses represent temporary impairment
      of
      the securities.
    Comprehensive
      Income
    The
      Company reports comprehensive income, which includes net loss, as well as
      certain other items, which result in a charge to equity during the period.
      
    | 
               Three
                months ended June 30 
              (in
                thousands) 
             | 
            
               Six
                months ended June 30 
              (in
                thousands) 
             | 
            ||||||||||||
| 
               2006 
             | 
            
               2007 
             | 
            
               2006 
             | 
            
               2007 
             | 
            ||||||||||
| 
               Unrealized
                gains (losses) during the period 
             | 
            
               $ 
             | 
            
               33 
             | 
            
               $ 
             | 
            
               248 
             | 
            
               $ 
             | 
            
               164 
             | 
            
               $ 
             | 
            
               491 
             | 
            |||||
| 
               Realized
                loss (gains) during the period 
             | 
            
               (3 
             | 
            
               ) 
             | 
            
               (198 
             | 
            
               ) 
             | 
            
               86 
             | 
            
               (221 
             | 
            
               ) 
             | 
          ||||||
| 
               Other
                comprehensive income(loss) 
             | 
            
               $ 
             | 
            
               30 
             | 
            
               $ 
             | 
            
               50 
             | 
            
               $ 
             | 
            
               250 
             | 
            
               $ 
             | 
            
               270 
             | 
            |||||
There
      are
      no income tax effects allocated to comprehensive income as the Company has
      no
      tax liabilities due to net operating losses.
    12
        Note
      5: DEBENTURE FINANCING
    | 
               Long
                term debt consists of the following: 
             | 
            |||||||
| 
               (in
                thousands) 
             | 
            |||||||
| 
               December
                31, 2006 
             | 
            
               June
                30, 2007 
             | 
            ||||||
| 
               October
                2003 
             | 
            
               $ 
             | 
            
               2,071 
             | 
            
               $ 
             | 
            
               - 
             | 
            |||
| 
               January
                2004 
             | 
            
               1,031 
             | 
            
               - 
             | 
            |||||
| 
               July
                2004 
             | 
            
               1,000 
             | 
            
               - 
             | 
            |||||
| 
               Total 
             | 
            
               4,102 
             | 
            
               - 
             | 
            |||||
| 
               Less
                Discounts 
             | 
            
               (231 
             | 
            
               ) 
             | 
            
               - 
             | 
            ||||
| 
               Total 
             | 
            
               3,871 
             | 
            
               - 
             | 
            |||||
| 
               Less
                current portion 
             | 
            
               3,871 
             | 
            
               - 
             | 
            |||||
| 
               Long
                term debt 
             | 
            
               $ 
             | 
            
               - 
             | 
            
               $ 
             | 
            
               - 
             | 
            |||
In
      June
      2007, the Company retired all remaining debt related to its convertible
      debentures issued in October 2003, January 2004 and July 2004. Of the
      outstanding debt of approximately $4,102,000, only $2,638,000 was required
      to be
      paid in new funds to retire the debentures, with the balance being covered
      by
      the Company’s advance receivable held as collateral by one of the debenture
      holders.
    October
      2003 Debentures
    The
      discount on the October 2003 Debentures is fully amortized; therefore, the
      Company did not record any financing costs for the three and six months ended
      June 30, 2006 and 2007, respectively. Interest expense for the three months
      ended June 30, 2006 and 2007, with regard to the October 2003 Debentures was
      approximately $36,000 for each period respectively. For the six months ended
      June 30, 2006 and 2007, interest expense related to these debentures was $72,000
      for each period respectively.
    January
      2004 Debentures
    The
      discount on the January 2004 Debentures is fully amortized; therefore, the
      Company did not record financing costs for the three months ended June 30,
      2006
      and 2007, respectively. Financing costs for the six months ended June 30, 2006
      and 2007, was approximately $49,000 and $0, respectively. Interest expense
      for
      the three months ended June 30, 2006 and 2007, with regard to the January 2004
      Debentures was approximately $29,000 and $18,000, respectively. For the six
      months ended June 30, 2006 and 2007, interest expense related to these
      debentures was $97,000 and $36,000, respectively.
    July
      2004 Debentures
    The
      Company recorded financing costs for the three months ended June 30, 2006 and
      2007, with regard to the July 2004 Debentures of $116,000 for each period
      respectively. For the six months ended June 30, 2007, the Company recorded
      financing costs of $253,000 and $231,000, respectively. Interest expense for
      the
      three months ended June 30, 2006 and 2007, with regard to the July 2004
      Debentures was approximately $19,000 and $17,000, respectively. For the six
      months ended June 30, 2006 and 2007, interest expense related to these
      debentures was $45,000 and $35,000, respectively.
    13
        NOTE
      6: EQUITY FINANCING
    For
      the
      six months ended June 30, 2007, Fusion Capital has purchased from the Company
      5,750,530 shares for aggregate gross proceeds of approximately $10,270,000
      pursuant to the April 2006 common stock purchase agreement between the Company
      and Fusion Capital.
    NOTE
      7: RECENT
      ACCOUNTING PRONOUNCEMENTS
    The
      Company adopted the provisions of FASB Interpretation No. 48, "Accounting for
      Uncertainty in Income Taxes" ("FIN 48") effective January 1, 2007. The purpose
      of FIN 48 is to clarify and set forth consistent rules for accounting for
      uncertain tax positions in accordance with Statement of Financial Accounting
      Standards No. 109, "Accounting for Income Taxes". The cumulative effect of
      applying the provisions of this interpretation are required to be reported
      separately as an adjustment to the opening balance of retained earnings in
      the
      year of adoption. The adoption of this standard did not have an impact on the
      financial condition or the results of our operations.
    On
      February 15, 2007, the FASB issued FASB Statement No. 159, The Fair Value Option
      for Financial Assets and Financial Liabilities - Including an Amendment of
      FASB
      Statement No. 115. This standard permits an entity to choose to measure many
      financial instruments and certain other items at fair value. This option is
      available to all entities, including not-for-profit organizations. Most of
      the
      provisions in Statement 159 are elective; however, the amendment to FASB
      Statement No. 115, Accounting for Certain Investments in Debt and Equity
      Securities, applies to all entities with available-for-sale and trading
      securities. Some requirements apply differently to entities that do not report
      net income. The FASB's stated objective in issuing this standard is as follows:
      "to improve financial reporting by providing entities with the opportunity
      to
      mitigate volatility in reported earnings caused by measuring related assets
      and
      liabilities differently without having to apply complex hedge accounting
      provisions".
    The
      fair
      value option established by Statement 159 permits all entities to choose to
      measure eligible items at fair value at specified election dates. A business
      entity will report unrealized gains and losses on items for which the fair
      value
      option has been elected in earnings (or another performance indicator if the
      business entity does not report earnings) at each subsequent reporting date.
      A
      not-for-profit organization will report unrealized gains and losses in its
      statement of activities or similar statement. The fair value option: (a) may
      be
      applied instrument by instrument, with a few exceptions, such as investments
      otherwise accounted for by the equity method; (b) is irrevocable (unless a
      new
      election date occurs); and (c) is applied only to entire instruments and not
      to
      portions of instruments.
    Statement
      159 is effective as of the beginning of an entity's first fiscal year that
      begins after November 15, 2007. 
      The
      impact of this statement has not been determined.
    ITEM
      2: Management's
      Discussion and Analysis of Financial Condition and Results of
      Operations.
    Special
      Note Regarding Forward-Looking Statements
    Certain
      statements in this document constitute "forwarding-looking statements" within
      the meaning of Section 27A of the Securities Act of 1933, as amended, and
      Section 21E of the Securities and Exchange Act of 1995 (collectively, the
      "Reform Act"). Certain, but not necessarily all, of such forward-looking
      statements can be identified by the use of forward-looking terminology such
      as
      "believes," "expects," "may," "will," "should," or "anticipates" or the negative
      thereof or other variations thereon or comparable terminology, or by discussions
      of strategy that involve risks and uncertainties. All statements other than
      statements of historical fact, included in this report regarding our financial
      position, business strategy and plans or objectives for future operations are
      forward-looking statements. Without limiting the broader description of
      forward-looking statements above, we specifically note that statements regarding
      potential drugs, their potential therapeutic effect, the possibility of
      obtaining regulatory approval, our ability to manufacture and sell any products,
      market acceptance or our ability to earn a profit from sales or licenses of
      any
      drugs or our ability to discover new drugs in the future are all forward-looking
      in nature.
    14
        Such
      forward-looking statements involve known and unknown risks, uncertainties and
      other factors, including but not limited to, the risk factors discussed below,
      which may cause the actual results, performance or achievements of Hemispherx
      and its subsidiaries to be materially different from any future results,
      performance or achievements expressed or implied by such forward-looking
      statements and other factors referenced in this report. We do not undertake
      and
      specifically decline any obligation to publicly release the results of any
      revisions which may be made to any forward-looking statement to reflect events
      or circumstances after the date of such statements or to reflect the occurrence
      of anticipated or unanticipated events. 
    Overview
    General
    We
      are a
      biopharmaceutical company engaged in the clinical development, manufacture
      and
      marketing of new drug entities based on natural immune system enhancing
      technologies for the treatment of viral and immune based acute and chronic
      disorders. We were founded in the early 1970s, as a contract researcher for
      the
      National Institutes of Health. Since that time, we have established a strong
      foundation of laboratory, pre-clinical, and clinical data with respect to the
      development of nucleic acids to enhance the natural antiviral defense system
      of
      the human body and to aid the development of therapeutic products for the
      treatment of acute and chronic diseases. We own a U.S. Food and Drug
      Administration (“FDA”) approved GMP (good manufacturing practice) manufacturing
      facility in New Jersey. Our flagship products include Ampligen® and Alferon N
      Injection®.
    Ampligen®
      is an experimental drug currently undergoing clinical development for the
      treatment of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (“ME/CFS” or
“CFS”), and clinical testing for treatment/prevention of avian and seasonal
      influenza. We have completed Phase III clinical trials using Ampligen® to treat
      ME/CFS patients and are currently in the process of preparing and filing a
      New
      Drug Application (“NDA”) with the FDA.
    Alferon
      N
      Injection® is the registered trademark for our injectable formulation of natural
      alpha interferon, which is approved by the FDA for the treatment of genital
      warts. Alferon N Injection® is also in clinical development for treating West
      Nile Virus (“WNV”).
    15
        New
      Accounting Pronouncements
    We
      adopted the provisions of FASB Interpretation No. 48, "Accounting for
      Uncertainty in Income Taxes" ("FIN 48") effective January 1, 2007. The purpose
      of FIN 48 is to clarify and set forth consistent rules for accounting for
      uncertain tax positions in accordance with Statement of Financial Accounting
      Standards No. 109, "Accounting for Income Taxes". The cumulative effect of
      applying the provisions of this interpretation are required to be reported
      separately as an adjustment to the opening balance of retained earnings in
      the
      year of adoption. The adoption of this standard did not have an impact on our
      financial condition or the results of our operations.
    On
      February 15, 2007, the FASB issued FASB Statement No. 159, The Fair Value Option
      for Financial Assets and Financial Liabilities - Including an Amendment of
      FASB
      Statement No. 115. This standard permits an entity to choose to measure many
      financial instruments and certain other items at fair value. This option is
      available to all entities, including not-for-profit organizations. Most of
      the
      provisions in Statement 159 are elective; however, the amendment to FASB
      Statement No. 115, Accounting for Certain Investments in Debt and Equity
      Securities, applies to all entities with available-for-sale and trading
      securities. Some requirements apply differently to entities that do not report
      net income. The FASB's stated objective in issuing this standard is as follows:
      "to improve financial reporting by providing entities with the opportunity
      to
      mitigate volatility in reported earnings caused by measuring related assets
      and
      liabilities differently without having to apply complex hedge accounting
      provisions".
    The
      fair
      value option established by Statement 159 permits all entities to choose to
      measure eligible items at fair value at specified election dates. A business
      entity will report unrealized gains and losses on items for which the fair
      value
      option has been elected in earnings (or another performance indicator if the
      business entity does not report earnings) at each subsequent reporting date.
      A
      not-for-profit organization will report unrealized gains and losses in its
      statement of activities or similar statement. The fair value option: (a) may
      be
      applied instrument by instrument, with a few exceptions, such as investments
      otherwise accounted for by the equity method; (b) is irrevocable (unless a
      new
      election date occurs); and (c) is applied only to entire instruments and not
      to
      portions of instruments.
    Statement
      159 is effective as of the beginning of an entity's first fiscal year that
      begins after November 15, 2007.  The impact of this statement has not been
      determined.
    Disclosure
      About Off-Balance
      Sheet Arrangements
    None.
    Critical
      Accounting Policies 
    There
      have been no material changes in our critical accounting policies and estimates
      from those disclosed in Item 7 of our Annual Report on Form 10-K for the year
      ended December 31, 2006. 
    16
        RESULTS
      OF OPERATIONS
    Three
      months ended June 30, 2006 versus three months ended June 30,
      2007
    Net
      loss
      Our
      net
      loss of approximately $3,925,000 for the three months ended June 30, 2007 was
      23% lower when compared to the same period in 2006. This $1,156,000 reduction
      in
      loss was primarily due to:
    | 1) | 
               Lower
                General & Administrative expenses of $543,000 principally related to a
                reduction in non-cash equity based compensation and lower accounting
                fees, 
             | 
          
| 2) | 
               An
                increase of $211,000 in interest and other income due to higher interest
                earned in the current period from the maturities of our marketable
                securities as compared to the previous
                period, 
             | 
          
| 3) | 
               Lower
                interest expense of $295,000 relating to the amortization of debt
                discounts on our convertible debentures and the incurring of liquidated
                damages in 2006 payable to our debenture holders resulting from us
                failing
                to timely file our 2005 Annual Report on Form
                10-K. 
             | 
          
Net
      loss
      per share was $0.05 for the current period versus $0.08 for the same period
      in
      2006.
    Revenues
    Revenues
      for the three months ended June 30, 2007 were $234,000 as compared to revenues
      of $247,000 for the same period in 2006. Ampligen® sold under the cost recovery
      clinical program was down $12,000 or 24% and Alferon N Injection®
      sales
      were flat as compared to the prior period. Ampligen® sold under the cost
      recovery clinical program is a product of physicians and ME/CFS patients
      applying to us to enroll in the program. This program has been in effect for
      several years and is offered as a treatment option to patients severely affected
      by CFS. As the name “cost recovery” implies, we have no gain or profit on these
      sales. The benefits to us include 1) physicians and patients becoming familiar
      with Ampligen® and 2) collection of clinical data relating to the patients’
treatment and results. We are altering our marketing strategy for Alferon N
      Injection®
      by
      relaunching the product via a collaborative marketing initiative between
      Hemispherx and a national Specialty Pharmacy network encompassing specialty
      pharmacists, pharmacies and targeted physician specialists. Such an effort
      is intended to focus our efforts in the most appropriate and productive market
      segment for the product. It is anticipated that such an initiative may
      generate a positive impact on Alferon® revenues in an efficient, cost effective
      manner.
    Production
      costs/cost of goods sold 
    Production/cost
      of goods sold decreased approximately $83,000 or 21% for the three months ended
      June 30, 2007 compared to the same period in 2006. This decrease was primarily
      due to: 1) lower production costs of approximately $17,000 relating to excess
      production capacity during the prior period as more effort was directed toward
      Ampligen® research and development and 2) a decrease in costs of goods sold of
      approximately $66,000. Cost of goods sold for the three months ended June 30,
      2006 and 2007 were $151,000 and $85,000 respectively. The primary reason for
      this decrease can be attributed to a fall in the number of vials sold during
      the
      current period. 
    17
        Research
      and Development costs
    Overall
      research and development costs for the three months ended June 30, 2007 were
      $2,534,000 as compared to $2,588,000 for the same period a year ago representing
      a slight decrease of $54,000.
    Our
      research and development costs include the direct cost associated with our
      effort to develop our lead product, Ampligen®, as a therapy in treating acute
      and chronic diseases. In addition to the costs related to the collection and
      processing of clinical data, our current expenditures include the costs of
      establishing our in-house polymer production facility and costs related to
      preparing and completing our NDA for the use of Ampligen® in treating
      CFS.
    We
      have
      filed certain sections of our Ampligen® NDA with the FDA for review and comment.
      As expected, the FDA reviewers have requested clarification in some areas and
      additional information in certain pre-clinical, chemistry, manufacturing and
      medical sections. We have engaged the services of additional Clinical Research
      Organizations (CROs) to assist in the responding to the various inquiries as
      well as conducting additional clinical exams and lab work. We have also added
      additional research personnel to assist the CROs. These personnel have
      experience at major pharmaceutical companies, i.e., J&J, Merck and
      GlaxoSmithKline. As previously reported, this process is affecting the
      finalization and completion of the NDA. We believe that in the long run, it
      may
      accelerate the review process; however, we cannot offer guidance on when the
      NDA
      will be deemed complete or when the review will be completed.
    As
      previously reported, we are actively engaged in broad-based experimental studies
      assessing the efficacy of our product, Ampligen®, Alferon N Injection® and
      Alferon® LDO against influenza viruses as an adjuvant and/or single agent
      antiviral with the Defence R&D Canada, the National Institute of Infectious
      Disease in Tokyo and various research affiliates of the National Institutes
      of
      Health in the United States.
    In
      June
      2007, we met with Dr. Hasegawa of the National Institute of Infectious Diseases
      in Japan and representatives of the Research Foundation of Microbial Diseases
      in
      Osaka University (Biken) to discuss the results of Dr. Hasegawa’s work in using
      Ampligen® as an adjuvant to make flu vaccines more effective. Further
      discussions are scheduled as to the extent and terms of a collaboration effort
      with Biken to develop a more effective flu vaccine using Ampligen® as an
      adjuvant.
    In
      June
      2007, we initiated a clinical trial in Australia using Ampligen® in combination
      with seasonal flu vaccines. This trial is expected to continue for several
      months, is being conducted in Australia’s winter season and focuses on
      populations at risk for virulent cases of influenza, especially those over
      the
      age of 60 years who historically may have weakened immune systems. The
      Australian clinical trial was prompted by the results from the pre-clinical
      work
      conducted by Dr. Hasegawa of the National Institute of Infectious diseases
      of
      Japan (see above comments). Thirty patients are anticipated to be enrolled
      in
      the Australian study, which will utilize a two dose Ampligen® regimen of 2mg per
      dose. This study is being monitored by Clinical Network Services Pty. Ltd.
      located in Brisbane, Australia. The clinical trials center of St. Vincent’s
      Hospital based in Darling Hurst, Australia will be conducting the trial.
      Prospective patients are being screened to be included in the clinical trials
      starting in August 2007. 
    18
        General
      and Administrative Expenses
    General
      and Administrative (“G&A”) expenses for the three months ended June 30, 2006
      and 2007 were approximately $2,086,000 and $1,543,000, respectively, reflecting
      a decrease of $543,000 or 26%. This
      decrease related primarily to a reduction in non-cash equity based compensation
      of $290,000 compared to the same period in 2006 as fewer stock options were
      granted to employees in the current period. Also, our accounting fees were
      down
      $428,000 from the same period a year ago primarily due to the charges incurred
      in 2006 related to the restatement of our financial statements. These decreases
      were slightly offset by increases in various other areas of G&A expense.
    Interest
      and Other Income
    Interest
      and other income for the three months ended June 30, 2006 and 2007 increased
      approximately $211,000 as compared to the same period a year earlier. The
      increase in interest and other income during the current period can primarily
      be
      attributed to higher interest realized on the maturity of our marketable
      securities as compared to the same period a year earlier. All funds in excess
      of
      our immediate need are invested in short-term securities. 
    Interest
      Expense and Financing Costs
    Interest
      expense and non-cash financing costs were approximately $183,000 for the three
      months ended June 30, 2007 versus $461,000 for the same period a year
      ago.
      The main
      reason for the decrease in interest expense and financing costs of $278,000
      can
      be attributed to the incurring of liquidated damages in 2006 payable to our
      debenture holders resulting from our failure to timely file our 2005 Annual
      Report on Form 10-K.
    Six
      months ended June 30, 2006 versus six months ended June 30,
      2007
    Net
      loss
      Our
      net
      loss of approximately $9,025,000 for the six months ended June 30, 2007 was
      18%
      lower when compared to the same period in 2006. This $1,975,000 reduction in
      loss was primarily due to:
    | 1) | 
               Lower
                General & Administrative expenses of $1,852,000 principally related to
                a reduction in non-cash equity based compensation and lower accounting
                fees with an offsetting increase in professional fees, salaries and
                wages
                and directors fees, 
             | 
          
| 2) | 
               An
                increase of $305,000 in interest and other income due to higher interest
                earned upon the maturity of our marketable securities as compared
                the same
                period a year ago, 
             | 
          
| 3) | 
               Lower
                interest expense of $295,000 relating to the amortization of debt
                discounts on our convertible debentures and the incurring of liquidated
                damages in 2006 payable to our debenture holders resulting from us
                failing
                to timely file our 2005 Annual Report on Form
                10-K, 
             | 
          
| 4) | 
               Higher
                Research and Development costs of $692,000 primarily due to an increase
                in
                the use of consultants related to the preparation and completion
                of our
                NDA for the use of Ampligen® in treating CFS.
 
             | 
          
Net
      loss
      per share was $0.13 for the current period versus $0.18 for the same period
      in
      2006.
    19
        Revenues
    Revenues
      for the six months ended June 30, 2007 were $489,000 as compared to revenues
      of
      $483,000 for the same period in 2006. Ampligen® sold under the cost recovery
      clinical program was down $30,000 or 29% while Alferon N Injection®
      sales
      were up $36,000 to $416,000 during the current period. The increase in Alferon
      N
      Injection®
      sales
      was due to a price increase instituted this year. Correspondingly, we have
      experienced a decline in the number of vials sold during the current quarter
      versus the same period a year ago as we continue to evidence increased
      competition from rival products. 
    Production
      costs/cost of goods sold 
    Production/cost
      of goods sold was approximately $551,000 during the current period representing
      a decrease of approximately $146,000 or 21% as compared to the same period
      in
      2006. This decrease was primarily due to lower production costs of $77,000
      relating to excess production capacity during the prior period as more effort
      was directed toward Ampligen® research and development and the NDA; and a
      decrease in costs of goods sold of $69,000. Costs of goods sold for the six
      months ended June 30, 2006 and 2007 was $247,000 and $178,000, respectively.
      This decrease can be attributed to reduction of the number of vials sold as
      compared to the prior period.
    Research
      and Development costs
    Overall
      research and development costs for the six months ended June 30, 2007 were
      $5,710,000 as compared to $5,018,000 for the same period a year ago representing
      an increase of $692,000.
      These
costs
      are
      primarily related to the collection and processing of clinical data, including
      the costs of establishing our in-house polymer production facility and the
      costs
      of preparing and completing our NDA for the use of Ampligen® in treating CFS.
      The increase can be attributed to an
      increase in the use of consultants related to the above areas.
    General
      and Administrative Expenses
    General
      and Administrative (“G&A”) expenses for the six months ended June 30, 2006
      and 2007 were approximately $5,178,000 and $3,326,000, respectively, reflecting
      a decrease of $1,852,000 or 36%. This
      decrease related primarily to a reduction in non-cash equity based compensation
      of $2,098,000 compared to the same period in 2006 as fewer stock options were
      granted to employees in the current period as well as lower accounting fees
      of
      $404,000 as compared to the prior period primarily due to the restatement of
      our
      financial statements for the period 2003 through 2005. These decreases were
      offset by various increases in other areas of general and administrative
      expense. 
    Interest
      and Other Income and Expense
    Interest
      and other income for the six months ended June 30, 2006 and 2007 increased
      approximately $305,000 as compared to the same period a year earlier. The
      increase in interest and other income during the current period was mainly
      due
      to higher interest earned upon the maturity of our marketable securities as
      compared the same period a year ago.
    20
        Interest
      Expense and Financing Costs
    Interest
      expense and non-cash financing costs were approximately $392,000 for the six
      months ended June 30, 2007 versus $750,000 for the same period a year
      ago.
      The main
      reason for the decrease in interest expense and financing costs of $358,000
      can
      be attributed to decreased amortization charges on debt discounts and
      the
      incurring of liquidated damages in 2006 payable to our debenture holders
      resulting from our failure to timely file our 2005 Annual Report on Form 10-K
      as
      we were in violation of provisions within our debenture agreements.
    Liquidity
      and Capital Resources
    Cash
      used
      in operating activities for the six months ended June 30, 2007 was $7,835,000.
      Cash provided by investing activities for the six months ending June 30, 2007,
      amounted to $3,546,000, primarily from the maturity and purchase of short-term
      investments. Cash provided by financing activities for the six months ended
      June
      30, 2007 amounted to $7,632,000. This was primarily due to proceeds received
      from the sale of our common stock of approximately $10,270,000. This was offset
      by the net repayment of our outstanding debt of $2,638,000 in June 2007. As
      of
      July 31, 2007 we had approximately $19,900,000 in
      cash
      and cash equivalents and short-term investments, or a decrease of approximately
      $2,129,000 from December 31, 2006. We anticipate that these funds should be
      sufficient to meet our operating cash requirements for the next 15 months.
      
    In
      June
      2007, the Company retired all remaining debt related to its convertible
      debentures issued in October 2003, January 2004 and July 2004. Of the
      outstanding debt of approximately $4,102,000, only $2,638,000 was required
      to be
      paid in new funds to retire the debentures, with the balance being covered
      by
      other cash and securities already held as collateral for the
      debentures.
    Equity
      Financing
    On
      April
      12, 2006, we entered into a common stock purchase agreement (the “2006 Purchase
      Agreement”) with Fusion Capital Fund II, LLC (“Fusion Capital”), pursuant to
      which Fusion Capital has agreed, under certain conditions, to purchase on each
      trading day $100,000 of our common stock up to an aggregate of $50.0 million
      over a period of approximately 25 months. Pursuant to the terms of the
      Registration Rights Agreement, dated as of April 12, 2006, we registered
      12,386,723 shares issuable to or issued to Fusion Capital under the Purchase
      Agreement. Through July 31, 2007, we have sold to Fusion Capital an aggregate
      of
      9,789,748 shares under the common stock purchase agreement for aggregate gross
      proceeds of $18,389,129 and issued 440,127 Commitment Shares. 
    Under
      the
      rules of the American Stock Exchange, in the event that we elect to sell more
      than 12,386,723 shares to Fusion Capital, we were required to seek stockholder
      approval. This approval was obtained on September 20, 2006. We also will be
      required to file a new registration statement and have it declared effective
      by
      the SEC in the event we elect to sell to Fusion Capital more than the 12,386,723
      shares previously registered. 
    We
      are
      using the proceeds from this financing for general corporate purposes.
    Because
      of our long-term capital requirements, we may seek to access the public equity
      market whenever conditions are favorable, even if we do not have an immediate
      need for additional capital at that time. Any additional funding may result
      in
      significant dilution and could involve the issuance of securities with rights,
      which are senior to those of existing stockholders. We may also need additional
      funding earlier than anticipated, and our cash requirements, in general, may
      vary materially from those now planned, for reasons including, but not limited
      to, changes in our research and development programs, clinical trials,
      competitive and technological advances, the regulatory processes, including
      the
      commercializing of Ampligen® products.
    21
        There
      can
      be no assurances that we will raise adequate funds from these or other sources,
      which may have a material adverse effect on our ability to develop our products.
      Also,
      we
      have the ability to curtail discretionary spending, including some research
      and
      development activities, if required to conserve cash.
    ITEM
      3: Quantitative and Qualitative Disclosures About Market
      Risk
    We
      had
      approximately $21,659,000 in cash and cash equivalents and short-term
      investments at June 30, 2007. To the extent that our cash and cash equivalents
      and short term investments exceed our near term funding needs, we generally
      invest the excess cash in three to twelve month interest bearing financial
      instruments. We employ established conservative policies and procedures to
      manage any risks with respect to investment exposure.
    Our
      financial instruments that are exposed to concentrations of credit risk consist
      primarily of cash and cash equivalents. We place our cash and cash equivalents
      with what management believes to be high credit quality institutions. At times
      such investments may be in excess of the FDIC insurance limit.
    We
      have
      not entered into, and do not expect to enter into, financial instruments for
      trading or hedging purposes.
    Item
      4: Controls and Procedures 
    Our
      Chairman of the Board (serving as the principal executive officer) and the
      Chief
      Financial Officer performed an evaluation of our disclosure controls and
      procedures, which have been designed to permit us to effectively identify and
      timely disclose important information. They concluded that the controls and
      procedures were effective as of June 30, 2007 to ensure that material
      information was accumulated and communicated to our management, including our
      Chief Executive Officer and Chief Financial Officer, as appropriate to allow
      timely decisions regarding required disclosure. During the quarter ended June
      30, 2007, we have made no change in our internal controls over financial
      reporting that has materially affected, or is reasonably likely to materially
      affect, our internal controls over financial reporting.
    Part
      II - OTHER INFORMATION
    Item
      1. Legal Proceedings
    We
      reported in our Form 10-Q for the period ending March 31, 2007 that in January
      2007 we filed an application in South Africa for the dissolution of Ribotech
      (PTY) Ltd. We have since determined to withdraw, and have withdrawn, this
      application.
    See
      our Form 10-Q for the period ending March 31, 2007 for previously reported
      legal
      proceedings.
    22
        ITEM
      1A. Risk Factors. 
    The
      following cautionary statements identify important factors that could cause
      our
      actual result to differ materially from those projected in the forward-looking
      statements made in this Form 10-Q. Among the key factors that have a direct
      bearing on our results of operations are:
    Risks
      Associated With Our Business
    No
      assurance of successful product development
    Ampligen®
      and related products. The development of Ampligen® and
      our
      other related products is subject to a number of significant risks.
      Ampligen® may
      be
      found to be ineffective or to have adverse side effects, fail to receive
      necessary regulatory clearances, be difficult to manufacture on a commercial
      scale, be uneconomical to market or be precluded from commercialization by
      proprietary right of third parties. Our products are in various stages of
      clinical and pre-clinical development and, require further clinical studies
      and
      appropriate regulatory approval processes before any such products can be
      marketed. We do not know when, if ever, Ampligen® or
      our
      other products will be generally available for commercial sale for any
      indication. Generally, only a small percentage of potential therapeutic products
      are eventually approved by the FDA for commercial sale. 
    We
      are in
      the registration process for an NDA with the FDA for approval to use Ampligen®
in the treatment of Chronic Fatigue Syndrome. We can provide no guidance as
      to
      the tentative date at which the compilation and filing of the NDA will be
      complete, as significant factors are outside our control including, without
      limitation, the ability and willingness of the independent clinical
      investigators to complete the requisite reports at an acceptable regulatory
      standard, the ability to collect overseas generated data, and the time required
      for our New Brunswick staff/facilities to interface with Hollister-Stier to
      assure compliance with manufacturing regulatory standards. Also, the timing
      of
      the FDA review process of the NDA is subject to the control of the FDA and
      could
      result in one of the following events; 1) approval to market Ampligen® for use
      in treating ME/CFS patients 2) require more research, development, and clinical
      work, 3) approval to market as well as conduct more testing, or 4) reject our
      NDA application. Given these variables, we are unable to project when material
      net cash inflows are expected to commence from the sale of Ampligen®.
    Alferon
      N
      Injection®. Although Alferon N Injection® is approved for marketing in the
      United States for the intra-lesional treatment of refractory or recurring
      external genital warts in patients 18 years of age or older; to date it has
      not
      been approved for other indications. We face many of the risks discussed above,
      with regard to developing this product for use to treat other
      ailments.
    Our
      drug and related technologies are investigational and subject to regulatory
      approval. If we are unable to obtain regulatory approval, our operations will
      be
      significantly affected.
    All
      of
      our drugs and associated technologies, other than Alferon N Injection®, are
      investigational and must receive prior regulatory approval by appropriate
      regulatory authorities for general use and are currently legally available
      only
      through clinical trials with specified disorders. At present, Alferon N
      Injection® is only approved for the intra-lesional treatment of refractory or
      recurring external genital warts in patients 18 years of age or older. Use
      of
      Alferon N Injection® for other indications will require regulatory
      approval.
    23
        Our
      products, including Ampligen®, are subject to extensive regulation by numerous
      governmental authorities in the U.S. and other countries, including, but not
      limited to, the FDA in the U.S., the Health Protection Branch (“HPB”) of Canada,
      and the Agency for the Evaluation of Medicinal Products (“EMEA”) in Europe.
      Obtaining regulatory approvals is a rigorous and lengthy process and requires
      the expenditure of substantial resources. In order to obtain final regulatory
      approval of a new drug, we must demonstrate to the satisfaction of the
      regulatory agency that the product is safe and effective for its intended uses
      and that we are capable of manufacturing the product to the applicable
      regulatory standards. We require regulatory approval in order to market
      Ampligen® or any other proposed product and receive product revenues or
      royalties. We cannot assure you that Ampligen® will ultimately be demonstrated
      to be safe or efficacious. In addition, while Ampligen® is authorized for use in
      clinical trials including a cost recovery program in the United States and
      Europe, we cannot assure you that additional clinical trial approvals will
      be
      authorized in the United States or in other countries, in a timely fashion
      or at
      all, or that we will complete these clinical trials. If Ampligen® or one of our
      other products does not receive regulatory approval in the U.S. or elsewhere,
      our operations most likely will be materially adversely affected. 
    Although
      preliminary in vitro testing indicates that Ampligen® enhances the effectiveness
      of different drug combinations on avian influenza, preliminary testing in the
      laboratory is not necessarily predictive of successful results in clinical
      testing or human treatment. 
    Ampligen®
      is undergoing pre-clinical testing for possible treatment of avian flu. Although
      preliminary in vitro testing indicates that Ampligen® enhances the effectiveness
      of different drug combinations on avian flu, preliminary testing in the
      laboratory is not necessarily predictive of successful results in clinical
      testing or human treatment. No assurance can be given that similar results
      will
      be observed in clinical trials. Use of Ampligen® in the treatment of avian flu
      requires prior regulatory approval. Only the FDA can determine whether a drug
      is
      safe, effective or promising for treating a specific application. As discussed
      in the prior risk factor, obtaining regulatory approvals is a rigorous and
      lengthy process. 
    In
      addition, Ampligen® is being tested on two strains of avian influenza virus.
      There are a number of strains and strains mutate. No assurance can be given
      that
      Ampligen® will be effective on any strains that might infect
      humans.
    We
      may continue to incur substantial losses and our future profitability is
      uncertain.
    We
      began
      operations in 1966 and last reported net profit from 1985 through 1987. Since
      1987, we have incurred substantial operating losses, as we pursued our clinical
      trial effort to get our experimental drug, Ampligen®, approved. As of June 30,
      2007, our accumulated deficit was approximately $176,076,000. We have not yet
      generated significant revenues from our products and may incur substantial
      and
      increased losses in the future. We cannot assure that we will ever achieve
      significant revenues from product sales or become profitable. We require, and
      will continue to require, the commitment of substantial resources to develop
      our
      products. We cannot assure that our product development efforts will be
      successfully completed or that required regulatory approvals will be obtained
      or
      that any products will be manufactured and marketed successfully, or be
      profitable. 
    24
        We
      may require additional financing which may not be
      available.
    The
      development of our products will require the commitment of substantial resources
      to conduct the time-consuming research, preclinical development, and clinical
      trials that are necessary to bring pharmaceutical products to market. As of
      July
      31, 2007, we had approximately $19,900,000 in
      cash
      and cash equivalents and short-term investments. We anticipate, but cannot
      assure, that these
      funds will be sufficient to meet our operating cash requirements for the next
      15
      months. 
    On
      April
      12, 2006, we entered into a common stock purchase agreement with Fusion Capital
      pursuant to which Fusion Capital has agreed, under certain conditions and with
      certain limitations, to purchase on each trading day $100,000 of our common
      stock up to an aggregate of $50,000,000 over a 25 month period (see Part I,
      Item
      2.
“Management's Discussion and Analysis of Financial Condition and Results of
      Operations; Liquidity and Capital Resources”).
      
    We
      only
      have the right to receive $100,000 per trading day under the agreement with
      Fusion Capital unless our stock price exceeds $1.90 by at least $0.10, in which
      case the daily amount may be increased under certain conditions as the price
      of
      our common stock increases. Fusion Capital shall not have the right nor the
      obligation to purchase any shares of our common stock on any trading days that
      the market price of our common stock is less than $1.00. We have registered
      an
      aggregate of 13,201,840 shares purchasable by Fusion Capital pursuant to the
      common stock purchase agreement (inclusive of up to 643,502 additional
      Commitment Shares) and, through August 6, 2007, we have sold to Fusion Capital
      an aggregate of 9,789,748 shares under the common stock purchase agreement
      for
      aggregate gross proceeds of approximately $18,389,000. Assuming a purchase
      price
      of $1.28 per share (the closing sale price of the common stock on August 6,
      2007) and the purchase by Fusion Capital of the remaining 1,953,473 shares
      (after issuing the remaining 203,375 Commitment Shares), total gross proceeds
      to
      us from the remaining shares would only be $2,500,445 ($20,889,445 in the
      aggregate under the common stock purchase agreement). Accordingly, depending
      upon the future market price of our common stock, we most likely will realize
      less than the maximum $50,000,000 proceeds from the sale of stock under the
      Purchase Agreement.
    In
      the
      event we elect to issue additional shares to Fusion Capital, we will be required
      to file a new registration statement and have it declared effective by the
      Securities and Exchange Commission. In addition, Fusion Capital cannot purchase
      more than 27,386,723 shares, inclusive of Commitment Shares under the common
      stock purchase agreement. 
    The
      extent to which we rely on Fusion Capital as a source of funding will depend
      on
      a number of factors including, the prevailing market price of our common stock
      and the extent to which we are able to secure working capital from other
      sources. 
    If
      obtaining sufficient financing from Fusion Capital were to prove unavailable
      or
      prohibitively dilutive and if we are unable to commercialize and sell Ampligen®
and/or increase sales of Alferon N Injection® or our other products, we will
      need to secure another source of funding in order to satisfy our working capital
      needs. Even if we are able to access the full $50,000,000 under the common
      stock
      purchase agreement with Fusion Capital, we may need to raise additional funds
      through additional equity or debt financing or from other sources in order
      to
      complete the necessary clinical trials and the regulatory approval processes
      including the commercializing of Ampligen® products. There can be no assurances
      that we will raise adequate funds which may have a material adverse effect
      on
      our ability to develop our products. Also, we have the ability to curtail
      discretionary spending, including some research and development activities,
      if
      required to conserve cash.
    25
        We
      may not be profitable unless we can protect our patents and/or receive approval
      for additional pending patents. 
    We
      need
      to preserve and acquire enforceable patents covering the use of Ampligen® for a
      particular disease in order to obtain exclusive rights for the commercial sale
      of Ampligen® for such disease. We obtained all rights to Alferon N Injection®,
      and we plan to preserve and acquire enforceable patents covering its use for
      existing and potentially new diseases. Our success depends, in large part,
      on
      our ability to preserve and obtain patent protection for our products and to
      obtain and preserve our trade secrets and expertise. Certain of our know-how
      and
      technology is not patentable, particularly the procedures for the manufacture
      of
      our experimental drug, Ampligen®, which is carried out according to standard
      operating procedure manuals. We have been issued certain patents including
      those
      on the use of Ampligen® and Ampligen® in combination with certain other drugs
      for the treatment of HIV. We also have been issued patents on the use of
      Ampligen® in combination with certain other drugs for the treatment of chronic
      Hepatitis B virus, chronic Hepatitis C virus, and a patent which affords
      protection on the use of Ampligen® in patients with Chronic Fatigue Syndrome. We
      have not yet been issued any patents in the United States for the use of
      AmpligenÒ
      as a
      sole treatment for any of the cancers, which we have sought to target. With
      regard to Alferon N Injection®, we have acquired from ISI its patents for
      natural alpha interferon produced from human peripheral blood leukocytes and
      its
      production process and we have filed a patent application for the use of
      Alferon® LDO in treating viral diseases including avian influenza. We cannot
      assure that our competitors will not seek and obtain patents regarding the
      use
      of similar products in combination with various other agents, for a particular
      target indication prior to our doing such. If we cannot protect our patents
      covering the use of our products for a particular disease, or obtain additional
      patents, we may not be able to successfully market our products. 
    The
      patent position of biotechnology and pharmaceutical firms is highly uncertain
      and involves complex legal and factual questions. 
    To
      date,
      no consistent policy has emerged regarding the breadth of protection afforded
      by
      pharmaceutical and biotechnology patents. There can be no assurance that new
      patent applications relating to our products or technology will result in
      patents being issued or that, if issued, such patents will afford meaningful
      protection against competitors with similar technology. It is generally
      anticipated that there may be significant litigation in the industry regarding
      patent and intellectual property rights. Such litigation could require
      substantial resources from us and we may not have the financial resources
      necessary to enforce the patent rights that we hold. No assurance can be made
      that our patents will provide competitive advantages for our products or will
      not be successfully challenged by competitors. No assurance can be given that
      patents do not exist or could not be filed which would have a materially adverse
      effect on our ability to develop or market our products or to obtain or maintain
      any competitive position that we may achieve with respect to our products.
      Our
      patents also may not prevent others from developing competitive products using
      related technology. 
    26
        There
      can be no assurance that we will be able to obtain necessary licenses if we
      cannot enforce patent rights we may hold. In addition, the failure of third
      parties from whom we currently license certain proprietary information or from
      whom we may be required to obtain such licenses in the future, to adequately
      enforce their rights to such proprietary information, could adversely affect
      the
      value of such licenses to us. 
    If
      we
      cannot enforce the patent rights we currently hold we may be required to obtain
      licenses from others to develop, manufacture or market our products. There
      can
      be no assurance that we would be able to obtain any such licenses on
      commercially reasonable terms, if at all. We currently license certain
      proprietary information from third parties, some of which may have been
      developed with government grants under circumstances where the government
      maintained certain rights with respect to the proprietary information developed.
      No assurances can be given that such third parties will adequately enforce
      any
      rights they may have or that the rights, if any, retained by the government
      will
      not adversely affect the value of our license. 
    There
      is
      no guarantee that our trade secrets will not be disclosed or known by our
      competitors.
    To
      protect our rights, we require certain employees and consultants to enter into
      confidentiality agreements with us. There can be no assurance that these
      agreements will not be breached, that we would have adequate and enforceable
      remedies for any breach, or that any trade secrets of ours will not otherwise
      become known or be independently developed by competitors. 
    If
      our distributors do not market our products successfully, we may not generate
      significant revenues or become profitable. 
    We
      have
      limited marketing and sales capability. We are dependent upon existing and,
      possibly future, marketing agreements and third party distribution agreements
      for our prod-ucts in order to generate significant revenues and become
      profitable. As a result, any revenues received by us will be dependent on the
      efforts of third parties, and there is no assurance that these efforts will
      be
      successful. Our agreement with Accredo offers the potential to provide some
      marketing and distribution capacity in the United States while agreements with
      Biovail Corporation and Laboratorios Del Dr. Esteve S.A. may provide a sales
      force in Canada, Spain and Portugal. 
    We
      cannot
      assure that our U.S. or foreign marketing partners will be able to successfully
      distribute our products, or that we will be able to establish future marketing
      or third party distribution agreements on terms acceptable to us, or that the
      cost of establishing these arrangements will not exceed any product revenues-.
      The failure to continue these arrangements or to achieve other such arrangements
      on satisfactory terms could have a materially adverse effect on us.
    There
      are no long-term agreements with suppliers of required materials. If we are
      unable to obtain the required raw materials, we may be required to scale back
      our operations or stop manufacturing Alferon N Injection® and/or
      Ampligen®.
    A
      number
      of essential materials are used in the production of Alferon N Injection®,
      including human white blood cells. We do not have long-term agreements for
      the
      supply of any of such materials. There can be no assurance we can enter into
      long-term supply agreements covering essential materials on commercially
      reasonable terms, if at all. 
    27
        There
      are
      a limited number of manufacturers in the United States available to provide
      the
      polymers for use in manufacturing Ampligen®. At present, we do not have any
      agreements with third parties for the supply of any of these polymers. We have
      established relevant manufacturing operations within our New Brunswick, New
      Jersey facility for the production of Ampligen® polymers from raw materials in
      order to obtain polymers on a more consistent manufacturing basis. The
      establishment of an Ampligen® polymers production line within our own
      facilities, may delay certain steps in the commercialization process,
      specifically, our Ampligen®
      NDA
      Registration process with the FDA. 
    If
      we are
      unable to obtain or manufacture the required polymers, we may be required to
      scale back our operations or stop manufacturing. The costs and availability
      of
      products and materials we need for the production of Ampligen® and the
      commercial production of Alferon N Injection® and other products which we may
      commercially produce are subject to fluctuation depending on a variety of
      factors beyond our control, including competitive factors, changes in
      technology, and FDA and other governmental regulations and there can be no
      assurance that we will be able to obtain such products and materials on terms
      acceptable to us or at all.
    There
      is no assurance that successful manufacture of a drug on a limited scale basis
      for investigational use will lead to a successful transition to commercial,
      large-scale production.
    Small
      changes in methods of manufacturing, including commercial scale-up, may affect
      the chemical structure of Ampligen® and other RNA drugs, as well as their safety
      and efficacy, and can, among other things, require new clinical studies and
      affect orphan drug status, particularly, market exclusivity rights, if any,
      under the Orphan Drug Act. The transition from limited production of
      pre-clinical and clinical research quantities to production of commercial
      quantities of our products will involve distinct management and technical
      challenges and will require additional management and technical personnel and
      capital to the extent such manufacturing is not handled by third parties. There
      can be no assurance that our manufacturing will be successful or that any given
      product will be determined to be safe and effective, capable of being
      manufactured economically in commercial quantities or successfully
      marketed.
    We
      have limited manufacturing experience and capacity.
    Ampligen®
      has been only produced in limited quantities for use in our clinical trials
      and
      we are dependent upon third party suppliers for substantially all of the
      production process. The failure to continue these arrangements or to achieve
      other such arrangements on satisfactory terms could have a material adverse
      affect on us. Also, to be successful, our products must be manufactured in
      commercial quantities in compliance with regulatory requirements and at
      acceptable costs. To the extent we are involved in the production process,
      our
      current facilities are not adequate for the production of our proposed products
      for large-scale commercialization, and we currently do not have adequate
      personnel to conduct commercial-scale manufacturing. We intend to utilize
      third-party facilities if and when the need arises or, if we are unable to
      do
      so, to build or acquire commercial-scale manufacturing facilities. We will
      need
      to comply with regulatory requirements for such facilities, including those
      of
      the FDA pertaining to current Good Manufacturing Practices (“cGMP”) regulations.
      There can be no assurance that such facilities can be used, built, or acquired
      on commercially acceptable terms, or that such facilities, if used, built,
      or
      acquired, will be adequate for our long-term needs.
    28
        We
      may not be profitable unless we can produce Ampligen® or other products in
      commercial quantities at costs acceptable to us.
    We
      have
      never produced Ampligen® or any other products in large commercial quantities.
      We must manufacture our products in compliance with regulatory requirements
      in
      large commercial quantities and at acceptable costs in order for us to be
      profitable. We intend to utilize third-party manufacturers and/or facilities
      if
      and when the need arises or, if we are unable to do so, to build or acquire
      commercial-scale manufacturing facili-ties. If we cannot manufacture commercial
      quantities of Ampligen® or enter into third party agreements for its manufacture
      at costs acceptable to us, our operations will be significantly affected. Also,
      each production lot of Alferon N Injection® is subject to FDA review and
      approval prior to releasing the lots to be sold. This review and approval
      process could take considerable time, which would delay our having product
      in
      inventory to sell. 
    Rapid
      technological change may render our products obsolete or
      non-competitive.
    The
      pharmaceutical and biotechnology industries are subject to rapid and substantial
      technological change. Technological competition from pharmaceutical and
      biotechnology companies, universities, governmental entities and others
      diversifying into the field is intense and is expected to increase. Most of
      these entities have significantly greater research and development capabilities
      than us, as well as substantial marketing, financial and managerial resources,
      and represent significant competition for us. There can be no assurance that
      developments by others will not render our products or technologies obsolete
      or
      noncompetitive or that we will be able to keep pace with technological
      developments.
    Our
      products may be subject to substantial competition. 
    Ampligen®.
      Competitors may be developing technologies that are, or in the future may be,
      the basis for competitive products. Some of these potential products may have
      an
      entirely different approach or means of accomplishing similar therapeutic
      effects to products being developed by us. These competing products may be
      more
      effective and less costly than our products. In addition, conventional drug
      therapy, surgery and other more familiar treatments may offer competition to
      our
      products. Furthermore, many of our competitors have significantly greater
      experience than us in pre-clinical testing and human clinical trials of
      pharmaceutical products and in obtaining FDA, HPB and other regulatory approvals
      of products. Accordingly, our competitors may succeed in obtaining FDA, HPB
      or
      other regulatory product approvals more rapidly than us. There are no drugs
      approved for commercial sale with respect to treating ME/CFS in the United
      States. The dominant competitors with drugs to treat disease indications in
      which we plan to address include Gilead Pharmaceutical, Pfizer, Bristol-Myers,
      Abbott Labs, Glaxo Smith Kline, Merck and Schering-Plough Corp. These potential
      competitors are among the largest pharmaceutical companies in the world, are
      well known to the public and the medical community, and have substantially
      greater financial resources, product development, and manufacturing and
      marketing capabilities than we have. Although we believe our principal advantage
      is the unique mechanism of action of Ampligen® on the immune system, we cannot
      assure that we will be able to compete.
    ALFERON
      N
      Injection®. Many competitors are among the largest pharmaceutical companies in
      the world, are well known to the public and the medical community, and have
      substantially greater financial resources, product development, and
      manufacturing and marketing capabilities than we have. Alferon N Injection®
currently competes with Schering’s injectable recombinant alpha interferon
      product (INTRON® A) for the treatment of genital warts. 3M Pharmaceuticals also
      offer competition from its immune-response modifier, Aldara®, a
      self-administered topical cream, for the treatment of external genital and
      perianal warts. In addition, Medigene recently received FDA approval for a
      self-administered ointment, VeregenTM, which is indicated for the topical
      treatment of external genital and perianal warts. Alferon N Injection® also
      competes with surgical, chemical, and other methods of treating genital warts.
      We cannot assess the impact products developed by our competitors, or advances
      in other methods of the treatment of genital warts, will have on the commercial
      viability of Alferon N Injection®. If and when we obtain additional approvals of
      uses of this product, we expect to compete primarily on the basis of product
      performance. Our competitors have developed or may develop products (containing
      either alpha or beta interferon or other therapeutic compounds) or other
      treatment modalities for those uses. There can be no assurance that, if we
      are
      able to obtain regulatory approval of Alferon N Injection® for the treatment of
      new indications, we will be able to achieve any significant penetration into
      those markets. In addition, because certain competitive products are not
      dependent on a source of human blood cells, such products may be able to be
      produced in greater volume and at a lower cost than Alferon N Injection®.
      Currently, our wholesale price on a per unit basis of Alferon N Injection® is
      higher than that of the competitive recombinant alpha and beta interferon
      products.
    29
        General.
      Other companies may succeed in developing products earlier than we do, obtaining
      approvals for such products from the FDA more rapidly than we do, or developing
      products that are more effective than those we may develop. While we will
      attempt to expand our technological capabilities in order to remain competitive,
      there can be no assurance that research and development by others or other
      medical advances will not render our technology or products obsolete or
      non-competitive or result in treatments or cures superior to any therapy we
      develop.
    Possible
      side effects from the use of Ampligen® or Alferon N Injection® could adversely
      affect potential revenues and physician/patient acceptability of our
      product.
    Ampligen®.
      We believe that Ampligen® has been generally well tolerated with a low incidence
      of clinical toxicity, particularly given the severely debilitating or life
      threatening diseases that have been treated. A mild flushing reaction has been
      observed in approximately 15% of patients treated in our various studies. This
      reaction is occasionally accompanied by a rapid heart beat, a tightness of
      the
      chest, urticaria (swelling of the skin), anxiety, shortness of breath,
      subjective reports of ''feeling hot'', sweating and nausea. The reaction is
      usually infusion-rate related and can generally be controlled by reducing the
      rate of infusion. Other adverse side effects include liver enzyme level
      elevations, diarrhea, itching, asthma, low blood pressure, photophobia, rash,
      transient visual disturbances, slow or irregular heart rate, decreases in
      platelets and white blood cell counts, anemia, dizziness, confusion, elevation
      of kidney function tests, occasional temporary hair loss and various flu-like
      symptoms, including fever, chills, fatigue, muscular aches, joint pains,
      headaches, nausea and vomiting. These flu-like side effects typically subside
      within several months. One or more of the potential side effects might deter
      usage of Ampligen® in certain clinical situations and therefore, could adversely
      affect potential revenues and physician/patient acceptability of our product.
      
    30
        Alferon
      N
      Injection®. At present, Alferon N Injection® is only approved for the
      intra-lesional (within the lesion) treatment of refractory or recurring external
      genital warts in adults. In clinical trials conducted for the treatment of
      genital warts with Alferon N Injection®, patients did not experience serious
      side effects; however, there can be no assurance that unexpected or unacceptable
      side effects will not be found in the future for this use or other potential
      uses of Alferon N Injection® which could threaten or limit such product’s
      usefulness.
    We
      may be subject to product liability claims from the use of Ampligen®, Alferon N
      Injection®, or other of our products which could negatively affect our future
      operations.
    We
      face
      an inherent business risk of exposure to product liability claims in the event
      that the use of Ampligen® or other of our products results in adverse effects.
      This liability might result from claims made directly by patients, hospitals,
      clinics or other consumers, or by pharmaceutical companies or others
      manufacturing these products on our behalf. Our future operations may be
      negatively affected from the litigation costs, settlement expenses and lost
      product sales inherent to these claims. While we will continue to attempt to
      take appro-priate precautions, we cannot assure that we will avoid significant
      product liability exposure. Although we currently maintain product liability
      insurance coverage, there can be no assurance that this insurance will provide
      adequate coverage against Ampligen® and/or Alferon N Injection® product
      liability claims. A successful product liability claim against us in excess
      of
      Ampligen®’s $1,000,000 in insurance coverage; $3,000,000 in aggregate, or in
      excess of Alferon N Injection®’s $5,000,000 in insurance coverage; $5,000,000 in
      aggregate; or for which coverage is not provided could have a negative effect
      on
      our business and financial condition.
    The
      loss of services of key personnel including Dr. William A. Carter could hurt
      our
      chances for success. 
    Our
      success is dependent on the continued efforts of Dr. William A. Carter because
      of his position as a pioneer in the field of nucleic acid drugs, his being
      the
      co-inventor of Ampligen®, and his knowledge of our overall activities, including
      patents and clinical trials. The loss of Dr. Carter’s services could have a
      material adverse effect on our operations and chances for success. We have
      secured key man life insurance in the amount of $2,000,000 on the life of Dr.
      Carter and we have an employment agreement with Dr. Carter that, as amended,
      runs until December 31, 2010. However, Dr. Carter has the right to terminate
      his
      employment upon not less than 30 days prior written notice. The loss of Dr.
      Carter or other personnel or the failure to recruit additional personnel as
      needed could have a materially adverse effect on our ability to achieve our
      objectives. 
    Uncertainty
      of health care reimbursement for our products. 
    Our
      ability to successfully commercialize our products will depend, in part, on
      the
      extent to which reimbursement for the cost of such products and related
      treatment will be available from government health administration authorities,
      private health coverage insurers and other organizations. Significant
      uncertainty exists as to the reimbursement status of newly approved health
      care
      products, and from time to time legislation is proposed, which, if adopted,
      could further restrict the prices charged by and/or amounts reimbursable to
      manufacturers of pharmaceutical products. We cannot predict what, if any,
      legislation will ultimately be adopted or the impact of such legislation on
      us.
      There can be no assurance that third party insurance companies will allow us
      to
      charge and receive payments for products sufficient to realize an appropriate
      return on our investment in product development. 
    31
        There
      are risks of liabilities associated with handling and disposing of hazardous
      materials. 
    Our
      business involves the controlled use of hazardous materials, carcinogenic
      chemicals, flammable solvents and various radioactive compounds. Although we
      believe that our safety procedures for handling and disposing of such materials
      comply in all material respects with the standards prescribed by applicable
      regulations, the risk of accidental contamination or injury from these materials
      cannot be completely eliminated. In the event of such an accident or the failure
      to comply with applicable regulations, we could be held liable for any damages
      that result, and any such liability could be significant. We do not maintain
      insurance coverage against such liabilities. 
    Risks
      Associated With an Investment in Our Common Stock
    The
      market price of our stock may be adversely affected by market
      volatility.
    The
      market price of our common stock has been and is likely to be volatile. In
      addition to general economic, political and market conditions, the price and
      trading volume of our stock could fluctuate widely in response to many factors,
      including: 
    | · | 
               announcements
                of the results of clinical trials by us or our
                competitors; 
             | 
          
| · | 
               adverse
                reactions to products; 
             | 
          
| · | 
               governmental
                approvals, delays in expected governmental approvals or withdrawals
                of any
                prior governmental approvals or public or regulatory agency concerns
                regarding the safety or effectiveness of our
                products; 
             | 
          
| · | 
               changes
                in U.S. or foreign regulatory policy during the period of product
                development; 
             | 
          
| · | 
               developments
                in patent or other proprietary rights, including any third party
                challenges of our intellectual property
                rights; 
             | 
          
| · | 
               announcements
                of technological innovations by us or our
                competitors; 
             | 
          
| · | 
               announcements
                of new products or new contracts by us or our
                competitors; 
             | 
          
| · | 
               actual
                or anticipated variations in our operating results due to the level
                of
                development expenses and other
                factors; 
             | 
          
| · | 
               changes
                in financial estimates by securities analysts and whether our earnings
                meet or exceed the estimates; 
             | 
          
| · | 
               conditions
                and trends in the pharmaceutical and other
                industries; 
             | 
          
new
      accounting standards; and
    | · | 
               the
                occurrence of any of the risks described in these "Risk
                Factors." 
             | 
          
Our
      common stock is listed for quotation on the American Stock Exchange. For the
      12-month period ended July 31, 2007, the price of our common stock has ranged
      from $1.24 to $2.49 per share. We expect the price of our common stock to remain
      volatile. The average daily trading volume of our common stock varies
      significantly. Our relatively low average volume and low average number of
      transactions per day may affect the ability of our stockholders to sell their
      shares in the public market at prevailing prices and a more active market may
      never develop.
    In
      the
      past, following periods of volatility in the market price of the securities
      of
      companies in our industry, securities class action litigation has often been
      instituted against companies in our industry. If we face securities litigation
      in the future, even if without merit or unsuccessful, it would result in
      substantial costs and a diversion of management attention and resources, which
      would negatively impact our business. 
    32
        Our
      stock price may be adversely affected if a significant amount of shares, are
      sold in the public market.
    We
      have
      registered 13,201,840 for sale by Fusion Capital and 143,658 shares by others,
      and may, in the future, register an additional 15,000,000 shares for sale by
      Fusion Capital under the common stock purchase agreement. As of August 6, 2007,
      approximately 710,358 shares of our common stock, constituted "restricted
      securities" as defined in Rule 144 under the Securities Act, 68,628 of which
      have been registered. Also, we have registered 6,571,072 shares issuable upon
      exercise of 135% of certain Warrants and upon exercise of certain other
      warrants. Registration of the shares permits the sale of the shares in the
      open
      market or in privately negotiated transactions without compliance with the
      requirements of Rule 144. To the extent the exercise price of the warrants
      is
      less than the market price of the common stock, the holders of the warrants
      are
      likely to exercise them and sell the underlying shares of common stock and
      to
      the extent that the conversion price and exercise price of these securities
      are
      adjusted pursuant to anti-dilution protection, the securities could be
      exercisable or convertible for even more shares of common stock. We also may
      issue shares to be used to meet our capital requirements or use shares to
      compensate employees, consultants and/or directors. We are unable to estimate
      the amount, timing or nature of future sales of outstanding common stock. Sales
      of substantial amounts of our common stock in the public market could cause
      the
      market price for our common stock to decrease. Furthermore, a decline in the
      price of our common stock would likely impede our ability to raise capital
      through the issuance of additional shares of common stock or other equity
      securities. 
    The
      sale of our common stock to Fusion Capital may cause dilution and the sale
      of
      the shares of common stock acquired by Fusion Capital and other shares
      registered for selling stockholders could cause the price of our common stock
      to
      decline.
    The
      sale
      by Fusion Capital and other selling stockholders of our common stock will
      increase the number of our publicly traded shares, which could depress the
      market price of our common stock. Moreover, the mere prospect of sales by Fusion
      Capital and other selling stockholders could depress the market price for our
      common stock. The issuance of shares to Fusion Capital under the common stock
      purchase agreement will dilute the equity interest of existing stockholders
      and
      could have an adverse effect on the market price of our common
      stock.
    The
      purchase price for the common stock to be sold to Fusion Capital pursuant to
      the
      common stock purchase agreement will fluctuate based on the price of our common
      stock. All shares sold to Fusion Capital are to be freely tradable. Fusion
      Capital may sell none, some or all of the shares of common stock purchased
      from
      us at any time. We expect that the shares offered by Fusion Capital will be
      sold
      over a period of in excess of two years. Depending upon market liquidity at
      the
      time, a sale of shares by Fusion at any given time could cause the trading
      price
      of our common stock to decline. The sale of a substantial number of shares
      of
      our common stock to Fusion Capital pursuant to the purchase agreement, or
      anticipation of such sales, could make it more difficult for us to sell equity
      or equity-related securities in the future at a time and at a price that we
      might otherwise wish to effect sales.
    33
        Provisions
      of our Certificate of Incorporation and Delaware law could defer a change of
      our
      management which could discourage or delay offers to acquire
      us.
    Provisions
      of our Certificate of Incorporation and Delaware law may make it more difficult
      for someone to acquire control of us or for our stockholders to remove existing
      management, and might discourage a third party from offering to acquire us,
      even
      if a change in control or in management would be beneficial to our stockholders.
      For example, our Certificate of Incorporation allows us to issue shares of
      preferred stock without any vote or further action by our stockholders. Our
      Board of Directors has the authority to fix and determine the relative rights
      and preferences of preferred stock. Our Board of Directors also has the
      authority to issue preferred stock without further stockholder approval. As
      a
      result, our Board of Directors could authorize the issuance of a series of
      preferred stock that would grant to holders the preferred right to our assets
      upon liquidation, the right to receive dividend payments before dividends are
      distributed to the holders of common stock and the right to the redemption
      of
      the shares, together with a premium, prior to the redemption of our common
      stock. In this regard, in November 2002, we adopted a stockholder rights plan
      and, under the Plan, our Board of Directors declared a dividend distribution
      of
      one Right for each outstanding share of Common Stock to stockholders of record
      at the close of business on November 29, 2002. Each Right initially entitles
      holders to buy one unit of preferred stock for $30.00. The Rights generally
      are
      not transferable apart from the common stock and will not be exercisable unless
      and until a person or group acquires or commences a tender or exchange offer
      to
      acquire, beneficial ownership of 15% or more of our common stock. However,
      for
      Dr. Carter, our chief executive officer, who already beneficially owns 7.9%
      of
      our common stock, the Plan’s threshold will be 20%, instead of 15%. The Rights
      will expire on November 19, 2012, and may be redeemed prior thereto at $.01
      per
      Right under certain circumstances.
    Because
      the risk factors referred to above could cause actual results or outcomes to
      differ materially from those expressed in any forward-looking statements made
      by
      us, you should not place undue reliance on any such forward-looking statements.
      Further, any forward-looking statement speaks only as of the date on which
      it is
      made and we undertake no obligation to update any forward-looking statement
      or
      statements to reflect events or circumstances after the date on which such
      statement is made or reflect the occurrence of unanticipated events. New factors
      emerge from time to time, and it is not possible for us to predict which will
      arise. In addition, we cannot assess the impact of each factor on our business
      or the extent to which any factor, or combination of factors, may cause actual
      results to differ materially from those contained in any forward-looking
      statements. Our research in clinical efforts may continue for the next several
      years and we may continue to incur losses due to clinical costs incurred in
      the
      development of Ampligen® for commercial application. Possible losses may
      fluctuate from quarter to quarter as a result of differences in the timing
      of
      significant expenses incurred and receipt of licensing fees and/or cost recovery
      treatment revenues in Europe, Canada and in the United States.
    ITEM
      2: Unregistered Sales of Equity Securities and Use of
      Proceeds 
    During
      the quarter ended June 30, 2007, we issued 1) 1,952,417 shares pursuant to
      the
      2006 Purchase Agreement with Fusion Capital, 2) an aggregate of 63,340 shares
      for services performed and an aggregate of 43,177 shares for the payment of
      interest. 
    34
        All
      of
      the foregoing transactions
      were conducted pursuant
      to the exemption from registration provided by Section 4(2) of the Securities
      Act of 1933.
      
    We
      did
      not repurchase any of our securities during the quarter ended June 30,
      2007.
    ITEM
      3: Defaults upon Senior Securities
    None.
      
    ITEM
      4: Submission of Matters to a Vote of Security Holders
    At
      the
      Company's Annual Meeting of Stockholders on June 20, 2007, stockholders approved
      the following:
    Election
      of Directors:
    | 
                 Nominees 
               | 
              
                 For 
               | 
              
                 | 
              
                 Withheld 
               | 
              ||||
| 
                 William
                  A. Carter 
               | 
              
                 50,927,906 
               | 
              
                 2,192,977 
               | 
              |||||
| 
                 Richard
                  C. Piani 
               | 
              
                 51,334,221 
               | 
              
                 1,786,662 
               | 
              |||||
| 
                 Ransom
                  W. Etheridge 
               | 
              
                 51,325,450 
               | 
              
                 1,795,433 
               | 
              |||||
| 
                 William
                  M. Mitchell. 
               | 
              
                 51,411,401 
               | 
              
                 1,709,482 
               | 
              |||||
| 
                 Iraj-Eqhbal
                  Kiani, Ph.D. 
               | 
              
                 51,050,302 
               | 
              
                 2,07,0581 
               | 
              |||||
| 
                 Steven
                  D. Spence 
               | 
              
                 51,307,350 
               | 
              
                 1,813,533 
               | 
              |||||
Ratification
      of the appointment of McGladrey & Pullen, LLP as the Company’s independent
      accountants:
    For:
      52,750,720 Against:
      311,323 Abstain:
      58,840
    Approval
      of the Hemispherx 2007 Equity Incentive Plan:
    For:
      5,788,350 Against:
      2,855,141 Abstain:
      58,085 Broker non-votes:44,901,317
    Total
      shares voted: 53,120,883 out of 71,608,110
      eligible
      to vote.
    ITEM
      5: Other Information
    None. 
    ITEM
      6: Exhibits 
    (a)
      Exhibits
    | 
                 31.1
                    
               | 
              
                 Certification
                  pursuant to Section 302 of the Sarbanes-Oxley Act of 2002 from
                  the
                  Company's Chief Executive Officer 
               | 
            |
| 
                 31.2
                   
               | 
              
                  Certification
                  pursuant to Section 302 of the Sarbanes-Oxley Act of 2002 from
                  the
                  Company's Chief Financial Officer 
               | 
            |
| 
                 32.1
                   
               | 
              
                  Certification
                  pursuant to Section 906 of the Sarbanes-Oxley Act of 2002 from
                  the
                  Company's Chief Executive Officer 
               | 
            |
| 
                 32.2
                   
               | 
              
                  Certification
                  pursuant to Section 906 of the Sarbanes-Oxley Act of 2002 from
                  the
                  Company's Chief Financial
                  Officer 
               | 
            
35
        SIGNATURES
    Pursuant
      to the requirements of the Securities Exchange Act of 1934, the registrant
      has duly caused this report to be signed on its behalf by the undersigned
      thereunto duly authorized. 
    | HEMISPHERx BIOPHARMA, INC. | ||
|   | 
              | 
              | 
          
| /S/ William A. Carter | ||
| 
               William A. Carter, M.D.  | 
          ||
| Chief Executive Officer & President | ||
|   | 
              | 
              | 
          
| /S/ Robert E. Peterson | ||
| 
               Robert E. Peterson  | 
          ||
| Chief Financial Officer | ||
| Date: August 9, 2007 | ||
36
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